DE69824856D1 - Rückgewinnung von viren aus zellkulturen durch verwendung einer hypertonischen salzlösung - Google Patents

Rückgewinnung von viren aus zellkulturen durch verwendung einer hypertonischen salzlösung

Info

Publication number
DE69824856D1
DE69824856D1 DE69824856T DE69824856T DE69824856D1 DE 69824856 D1 DE69824856 D1 DE 69824856D1 DE 69824856 T DE69824856 T DE 69824856T DE 69824856 T DE69824856 T DE 69824856T DE 69824856 D1 DE69824856 D1 DE 69824856D1
Authority
DE
Germany
Prior art keywords
virus
salt solution
viruses
recovery
cell cultures
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69824856T
Other languages
English (en)
Other versions
DE69824856T2 (de
Inventor
Michael Denis Johnston
Roderic Simon O'keeffe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xenova Research Ltd
Original Assignee
Xenova Research Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10817061&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69824856(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xenova Research Ltd filed Critical Xenova Research Ltd
Publication of DE69824856D1 publication Critical patent/DE69824856D1/de
Application granted granted Critical
Publication of DE69824856T2 publication Critical patent/DE69824856T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16651—Methods of production or purification of viral material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69824856T 1997-08-07 1998-08-07 Rückgewinnung von viren aus zellkulturen durch verwendung einer hypertonischen salzlösung Expired - Lifetime DE69824856T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9716611.0A GB9716611D0 (en) 1997-08-07 1997-08-07 Virus preparations and methods
GB9716611 1997-08-07
PCT/GB1998/002387 WO1999007834A1 (en) 1997-08-07 1998-08-07 Recovery of virus from cell culture using a hypertonic salt solution

Publications (2)

Publication Number Publication Date
DE69824856D1 true DE69824856D1 (de) 2004-08-05
DE69824856T2 DE69824856T2 (de) 2005-07-21

Family

ID=10817061

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69824856T Expired - Lifetime DE69824856T2 (de) 1997-08-07 1998-08-07 Rückgewinnung von viren aus zellkulturen durch verwendung einer hypertonischen salzlösung

Country Status (11)

Country Link
EP (1) EP1002055B2 (de)
JP (2) JP2001512675A (de)
AT (1) ATE270325T1 (de)
AU (1) AU8737298A (de)
CA (1) CA2299628A1 (de)
DE (1) DE69824856T2 (de)
DK (1) DK1002055T3 (de)
ES (1) ES2224422T3 (de)
GB (1) GB9716611D0 (de)
PT (1) PT1002055E (de)
WO (1) WO1999007834A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60233061D1 (de) 2001-09-06 2009-09-03 Alphavax Inc Alphavirus replikon-vektorsysteme
BRPI0317276B8 (pt) * 2002-12-13 2021-05-25 Alphavax Inc método para a preparação de partículas de replicon de alfavírus (arps)
KR101454842B1 (ko) 2003-03-20 2014-11-04 알파벡스, 인크. 개선된 알파바이러스 레플리콘 및 헬퍼 구축물
CN100398642C (zh) * 2003-06-20 2008-07-02 迈克必斯生物系统公司 病毒生产的改进
US7270990B2 (en) 2003-06-20 2007-09-18 Microbix Biosystems, Inc. Virus production
PT1651666E (pt) 2003-07-11 2009-08-28 Alphavax Inc Vacinas de citomegalovírus à base de alfavírus
PL2947149T3 (pl) 2007-06-21 2018-09-28 Alphavax, Inc. Kasety bez promotora do ekspresji alfawirusowych białek strukturalnych
JP5980947B2 (ja) 2012-11-22 2016-08-31 旭化成メディカル株式会社 高感染価のパルボウイルスの生産方法
CN104250639A (zh) * 2013-06-28 2014-12-31 北京奥源和力生物技术有限公司 一种收获和生产病毒的方法
EP3372677B8 (de) 2015-11-06 2019-09-25 Asahi Kasei Medical Co., Ltd. Verfahren zur herstellung eines parvovirus mit hohem infektiositätstiter und hoher reinheit
US10626376B2 (en) 2016-11-14 2020-04-21 St. Jude Children's Research Hospital Method for isolating and purifying adeno-associated virus particles using salt
JP2023532759A (ja) * 2020-07-10 2023-07-31 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 細胞培養物から精製されたラブドウイルスを製造するための方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5204257A (en) * 1991-04-29 1993-04-20 Autogen Instruments, Inc. Method of recovering bacteriophage
CA2097019C (en) * 1992-06-04 2007-07-24 Philip J. Provost Process for attenuated varicella zoster virus vaccine production

Also Published As

Publication number Publication date
EP1002055A1 (de) 2000-05-24
DK1002055T3 (da) 2004-10-25
CA2299628A1 (en) 1999-02-18
JP2001512675A (ja) 2001-08-28
EP1002055B1 (de) 2004-06-30
ATE270325T1 (de) 2004-07-15
GB9716611D0 (en) 1997-10-08
JP2009297036A (ja) 2009-12-24
WO1999007834A1 (en) 1999-02-18
DE69824856T2 (de) 2005-07-21
AU8737298A (en) 1999-03-01
PT1002055E (pt) 2004-10-29
EP1002055B2 (de) 2010-04-14
ES2224422T3 (es) 2005-03-01

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8332 No legal effect for de