DE69815828D1 - Verwendung von mikropartikeln, auf denen ein protein und ein antikörper adsorbiert sind, zur herstellung eines arzneimittels zur intranasalen verabreichung - Google Patents

Verwendung von mikropartikeln, auf denen ein protein und ein antikörper adsorbiert sind, zur herstellung eines arzneimittels zur intranasalen verabreichung

Info

Publication number
DE69815828D1
DE69815828D1 DE69815828T DE69815828T DE69815828D1 DE 69815828 D1 DE69815828 D1 DE 69815828D1 DE 69815828 T DE69815828 T DE 69815828T DE 69815828 T DE69815828 T DE 69815828T DE 69815828 D1 DE69815828 D1 DE 69815828D1
Authority
DE
Germany
Prior art keywords
microparticles
protein
adsorbed
antibody
intranasal administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69815828T
Other languages
English (en)
Other versions
DE69815828T2 (de
Inventor
Dario Cremaschi
Cristina Porta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Acraf SpA
Original Assignee
Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco ACRAF SpA filed Critical Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Application granted granted Critical
Publication of DE69815828D1 publication Critical patent/DE69815828D1/de
Publication of DE69815828T2 publication Critical patent/DE69815828T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DE69815828T 1997-04-14 1998-04-08 Verwendung von mikropartikeln, auf denen ein protein und ein antikörper adsorbiert sind, zur herstellung eines arzneimittels zur intranasalen verabreichung Expired - Fee Related DE69815828T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT97MI000856A IT1291559B1 (it) 1997-04-14 1997-04-14 Uso di microparticelle su cui sono stati adsorbiti una proteina ed un anticorpo per preparare una composizione farmaceutica somministrabile
ITMI970856 1997-04-14
PCT/EP1998/002214 WO1998046209A1 (en) 1997-04-14 1998-04-08 Use of microparticles having a protein and an antibody adsorbed thereon for preparing a pharmaceutical composition for intranasal administration

Publications (2)

Publication Number Publication Date
DE69815828D1 true DE69815828D1 (de) 2003-07-31
DE69815828T2 DE69815828T2 (de) 2004-05-19

Family

ID=11376872

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69815828T Expired - Fee Related DE69815828T2 (de) 1997-04-14 1998-04-08 Verwendung von mikropartikeln, auf denen ein protein und ein antikörper adsorbiert sind, zur herstellung eines arzneimittels zur intranasalen verabreichung

Country Status (24)

Country Link
US (1) US7235522B2 (de)
EP (1) EP0971703B9 (de)
JP (1) JP2002503222A (de)
KR (1) KR100507449B1 (de)
CN (1) CN1135970C (de)
AT (1) ATE243502T1 (de)
AU (1) AU742079B2 (de)
BG (1) BG64269B1 (de)
CA (1) CA2288970C (de)
CZ (1) CZ298935B6 (de)
DE (1) DE69815828T2 (de)
DK (1) DK0971703T3 (de)
EA (1) EA002324B1 (de)
ES (1) ES2201492T3 (de)
GE (1) GEP20022646B (de)
HU (1) HU225523B1 (de)
IL (1) IL132114A (de)
IT (1) IT1291559B1 (de)
PL (1) PL189918B1 (de)
PT (1) PT971703E (de)
SK (1) SK282398B6 (de)
TR (1) TR199902536T2 (de)
UA (1) UA62961C2 (de)
WO (1) WO1998046209A1 (de)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2050425A1 (en) * 1990-09-03 1992-03-04 Yoshiaki Uda Pharmaceutical composition and its mucous use
RU2022562C1 (ru) * 1992-05-06 1994-11-15 Рубальский Олег Васильевич Способ лечения вирусной инфекции кожи и слизистых оболочек
GB9311454D0 (en) * 1993-06-03 1993-07-21 Agricultural & Food Res Pharmaceutical compositions
JP3414539B2 (ja) * 1994-05-11 2003-06-09 有限会社ドット 経鼻吸収用組成物
US5879712A (en) * 1995-06-07 1999-03-09 Sri International Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced

Also Published As

Publication number Publication date
WO1998046209A1 (en) 1998-10-22
HUP0001752A2 (hu) 2000-10-28
IL132114A0 (en) 2001-03-19
PT971703E (pt) 2003-11-28
EP0971703B9 (de) 2003-11-05
CN1252712A (zh) 2000-05-10
JP2002503222A (ja) 2002-01-29
US7235522B2 (en) 2007-06-26
HU225523B1 (en) 2007-01-29
ES2201492T3 (es) 2004-03-16
CA2288970A1 (en) 1998-10-22
BG103873A (en) 2000-06-30
ITMI970856A1 (it) 1998-10-14
EP0971703A1 (de) 2000-01-19
IT1291559B1 (it) 1999-01-11
PL189918B1 (pl) 2005-10-31
CA2288970C (en) 2006-05-30
AU742079B2 (en) 2001-12-20
TR199902536T2 (xx) 2000-02-21
BG64269B1 (bg) 2004-08-31
ATE243502T1 (de) 2003-07-15
KR20010006267A (ko) 2001-01-26
US20020058069A1 (en) 2002-05-16
UA62961C2 (en) 2004-01-15
DE69815828T2 (de) 2004-05-19
EA199900934A1 (ru) 2000-04-24
KR100507449B1 (ko) 2005-08-10
HUP0001752A3 (en) 2001-10-29
EP0971703B1 (de) 2003-06-25
AU7526098A (en) 1998-11-11
CZ298935B6 (cs) 2008-03-12
CN1135970C (zh) 2004-01-28
CZ362499A3 (cs) 2000-04-12
PL336207A1 (en) 2000-06-05
EA002324B1 (ru) 2002-04-25
DK0971703T3 (da) 2003-10-20
GEP20022646B (en) 2002-03-25
IL132114A (en) 2004-07-25
SK142299A3 (en) 2000-09-12
SK282398B6 (sk) 2002-01-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee