DE69811382D1 - Carbapenemderivate und herstellungsverfahren dafür - Google Patents
Carbapenemderivate und herstellungsverfahren dafürInfo
- Publication number
- DE69811382D1 DE69811382D1 DE69811382T DE69811382T DE69811382D1 DE 69811382 D1 DE69811382 D1 DE 69811382D1 DE 69811382 T DE69811382 T DE 69811382T DE 69811382 T DE69811382 T DE 69811382T DE 69811382 D1 DE69811382 D1 DE 69811382D1
- Authority
- DE
- Germany
- Prior art keywords
- derivatives
- carbapen
- production method
- method therefor
- carbapenem derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/02—Preparation
- C07D477/04—Preparation by forming the ring or condensed ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR19970047460 | 1997-09-13 | ||
PCT/KR1998/000255 WO1999014218A1 (en) | 1997-09-13 | 1998-08-21 | Carbapenem derivatives and a preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69811382D1 true DE69811382D1 (de) | 2003-03-20 |
DE69811382T2 DE69811382T2 (de) | 2003-10-23 |
Family
ID=19521343
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69811382T Expired - Fee Related DE69811382T2 (de) | 1997-09-13 | 1998-08-21 | Carbapenemderivate und herstellungsverfahren dafür |
Country Status (8)
Country | Link |
---|---|
US (1) | US6436921B1 (de) |
EP (1) | EP1023294B1 (de) |
JP (1) | JP3403173B2 (de) |
KR (1) | KR100327758B1 (de) |
AT (1) | ATE232533T1 (de) |
CA (1) | CA2303446C (de) |
DE (1) | DE69811382T2 (de) |
WO (1) | WO1999014218A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6649756B2 (en) | 2000-07-13 | 2003-11-18 | Wyeth, Five Giralda Farms | Process improvement in the preparation of (4r, 5s, 6s)-3-[[(2r,3r)-2-[[[(s)-2-amino-3-methyl-1-oxobutyl]amino]methyl]tetrahydro-3-furanyl]thio]-6-[(r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid |
PT1926732E (pt) | 2005-09-05 | 2013-12-27 | Ranbaxy Lab Ltd | Processo para a preparação de compostos de carbapenem |
BRPI0616563A2 (pt) * | 2005-09-15 | 2012-12-25 | Orchid Chemicals & Pharm Ltd | processo melhorado para a preparaÇço de antibiàtico betalactÂmico |
JP5406181B2 (ja) * | 2007-06-28 | 2014-02-05 | ケービーピー・バイオサイエンシズ・カンパニー・リミテッド | 新規カルバペネム誘導体 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1283906C (en) * | 1983-05-09 | 1991-05-07 | Makoto Sunagawa | .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF |
FI96863C (fi) | 1990-02-23 | 1996-09-10 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten /2-(1-homopiperatsiinikarbonyyli)pyrrolidin-4-yylitio/-6-(1-hydroksietyyli)-1-karbapen-2-eemi-3-karboksylaattisuolojen valmistamiseksi |
-
1998
- 1998-08-21 WO PCT/KR1998/000255 patent/WO1999014218A1/en active IP Right Grant
- 1998-08-21 EP EP98941881A patent/EP1023294B1/de not_active Expired - Lifetime
- 1998-08-21 US US09/508,656 patent/US6436921B1/en not_active Expired - Fee Related
- 1998-08-21 CA CA002303446A patent/CA2303446C/en not_active Expired - Fee Related
- 1998-08-21 AT AT98941881T patent/ATE232533T1/de not_active IP Right Cessation
- 1998-08-21 DE DE69811382T patent/DE69811382T2/de not_active Expired - Fee Related
- 1998-08-21 JP JP2000511767A patent/JP3403173B2/ja not_active Expired - Fee Related
- 1998-09-03 KR KR1019980036299A patent/KR100327758B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR19990029501A (ko) | 1999-04-26 |
KR100327758B1 (ko) | 2002-09-09 |
CA2303446C (en) | 2004-10-26 |
EP1023294A1 (de) | 2000-08-02 |
EP1023294B1 (de) | 2003-02-12 |
WO1999014218A1 (en) | 1999-03-25 |
JP3403173B2 (ja) | 2003-05-06 |
DE69811382T2 (de) | 2003-10-23 |
CA2303446A1 (en) | 1999-03-25 |
US6436921B1 (en) | 2002-08-20 |
JP2001516759A (ja) | 2001-10-02 |
ATE232533T1 (de) | 2003-02-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |