AU2000265939A1 - Novel pseudoerythromycin derivatives - Google Patents

Novel pseudoerythromycin derivatives

Info

Publication number
AU2000265939A1
AU2000265939A1 AU2000265939A AU6593900A AU2000265939A1 AU 2000265939 A1 AU2000265939 A1 AU 2000265939A1 AU 2000265939 A AU2000265939 A AU 2000265939A AU 6593900 A AU6593900 A AU 6593900A AU 2000265939 A1 AU2000265939 A1 AU 2000265939A1
Authority
AU
Australia
Prior art keywords
derivatives
novel
novel pseudoerythromycin
pseudoerythromycin derivatives
psedoerythromycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2000265939A
Inventor
Yuzuru Iwai
Tohru Nagamitsu
Satoshi Omura
Toshiaki Sunazuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kitasato Institute
Original Assignee
Kitasato Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Institute filed Critical Kitasato Institute
Publication of AU2000265939A1 publication Critical patent/AU2000265939A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention is to obtain novel anti-inflammatory agents having decreased antibacterial activity and increased anti-inflammatory action, and is psedoerythromycin derivatives represented by the following general formula ÄIÜ, <CHEM> wherein R1 and R2 are same or different and each represents H, alkyl, alkynyl, acyl or sulfonyl, in which these groups may optionally have substituents, and Me indicates methyl.
AU2000265939A 2000-08-17 2000-08-17 Novel pseudoerythromycin derivatives Abandoned AU2000265939A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2000/005503 WO2002014338A1 (en) 2000-08-17 2000-08-17 Novel pseudoerythromycin derivatives

Publications (1)

Publication Number Publication Date
AU2000265939A1 true AU2000265939A1 (en) 2002-02-25

Family

ID=11736361

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2000265939A Abandoned AU2000265939A1 (en) 2000-08-17 2000-08-17 Novel pseudoerythromycin derivatives

Country Status (11)

Country Link
US (1) US6734292B1 (en)
EP (2) EP1256587B1 (en)
KR (6) KR20040074096A (en)
AT (2) ATE321770T1 (en)
AU (1) AU2000265939A1 (en)
CA (1) CA2386828C (en)
DE (2) DE60027015T2 (en)
DK (1) DK1489090T3 (en)
ES (2) ES2257720T3 (en)
PT (1) PT1489090E (en)
WO (1) WO2002014338A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2359244C (en) 1999-01-13 2013-10-08 Bayer Corporation .omega.-carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
US8124630B2 (en) 1999-01-13 2012-02-28 Bayer Healthcare Llc ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
DK1478358T3 (en) 2002-02-11 2013-10-07 Bayer Healthcare Llc Sorafenibtosylate for the treatment of diseases characterized by abnormal angiogenesis
WO2003068229A1 (en) 2002-02-11 2003-08-21 Bayer Pharmaceuticals Corporation Pyridine, quinoline, and isoquinoline n-oxides as kinase inhibitors
US20040067896A1 (en) * 2002-07-25 2004-04-08 The Kitasato Institute Novel pseudoerythromycin derivatives
UY28213A1 (en) 2003-02-28 2004-09-30 Bayer Pharmaceuticals Corp NEW CYANOPIRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER AND OTHER DISORDERS.
PT1626714E (en) 2003-05-20 2007-08-24 Bayer Pharmaceuticals Corp Diaryl ureas for diseases mediated by pdgfr
ES2297490T3 (en) 2003-07-23 2008-05-01 Bayer Pharmaceuticals Corporation OMEGA-CARBOXIARILDIFENILUREA FLUORO REPLACED FOR THE TREATMENT AND PREVENTION OF DISEASES AND AFFECTIONS.
US7419962B2 (en) * 2004-12-07 2008-09-02 Enanta Pharmaceuticals, Inc. 3,6-bicyclolides
US7229972B2 (en) * 2004-12-07 2007-06-12 Enanta Pharmaceuticals, Inc. 3,6-Bicyclolides
US8278281B2 (en) 2005-08-24 2012-10-02 Rib-X Pharmaceuticals, Inc. Triazole compounds and methods of making and using the same
JP5118973B2 (en) 2005-10-14 2013-01-16 学校法人北里研究所 New dihydropseudoerythromycin derivatives
US7407942B2 (en) * 2006-03-29 2008-08-05 Emata Pharmaceuticals, Inc 3,6-bridged 9,12-oxolides
US8097419B2 (en) 2006-09-12 2012-01-17 Longhorn Vaccines & Diagnostics Llc Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009
US8652782B2 (en) 2006-09-12 2014-02-18 Longhorn Vaccines & Diagnostics, Llc Compositions and methods for detecting, identifying and quantitating mycobacterial-specific nucleic acids
US20090098527A1 (en) * 2006-09-12 2009-04-16 Fischer Gerald W Biological organism identification product and methods
US9481912B2 (en) 2006-09-12 2016-11-01 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and identifying nucleic acid sequences in biological samples
US8080645B2 (en) * 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
US11041215B2 (en) 2007-08-24 2021-06-22 Longhorn Vaccines And Diagnostics, Llc PCR ready compositions and methods for detecting and identifying nucleic acid sequences
US9683256B2 (en) 2007-10-01 2017-06-20 Longhorn Vaccines And Diagnostics, Llc Biological specimen collection and transport system
US10004799B2 (en) 2007-08-27 2018-06-26 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
EP2772267B1 (en) 2007-08-27 2016-04-27 Longhorn Vaccines and Diagnostics, LLC Immunogenic compositions and methods
US11041216B2 (en) 2007-10-01 2021-06-22 Longhorn Vaccines And Diagnostics, Llc Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples
EP3020832A1 (en) 2007-10-01 2016-05-18 Longhorn Vaccines and Diagnostics, LLC Biological specimen collection and transport system and methods of use
JP5733601B2 (en) * 2010-07-13 2015-06-10 国立大学法人 千葉大学 Preventive and / or therapeutic agent for fulminant inflammation
CA2863083C (en) 2012-01-26 2023-09-19 Longhorn Vaccines And Diagnostics, Llc Composite antigenic sequences and vaccines
CA2985652C (en) 2015-05-14 2020-03-10 Gerald W. FISHER Rapid methods for the extraction of nucleic acids from biological samples

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106961A (en) 1987-05-26 1992-04-21 Eli Lilly And Company Erythromycin ring-contracted derivatives
CA1321581C (en) * 1987-05-26 1993-08-24 Herbert A. Kirst Ring-contracted macrolides
US4920102A (en) 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
US5554605A (en) 1991-04-09 1996-09-10 Abbott Laboratories Macrocyclic lactam prokinetic agents
KR100222014B1 (en) 1991-04-09 1999-10-01 스티븐 에프. 웨인스톡 Macrocyclic lactam prokinetic agents, process for preparing thereof and pharmaceutical composition containing them
DE4200145A1 (en) * 1992-01-07 1993-07-08 Kali Chemie Pharma Gmbh 7,10-EPOXY-OXACYCLODODANE DERIVATIVES, METHODS AND INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE COMPOUNDS
DE19644195A1 (en) * 1996-10-24 1998-04-30 Solvay Pharm Gmbh 10,13,15-Trioxatricyclo [9.2.1.1. · 9 ·. · 6 ·] -pentadecanone derivatives, processes for their preparation and pharmaceuticals containing these compounds
DE19805822B4 (en) * 1998-02-13 2009-02-05 Solvay Pharmaceuticals Gmbh 11-Acetyl-12,13-dioxabicyclo [8.2.1] tridecenone derivatives, process for their preparation and medicaments containing these compounds

Also Published As

Publication number Publication date
EP1489090B1 (en) 2006-02-01
WO2002014338A1 (en) 2002-02-21
KR20040066188A (en) 2004-07-23
DE60025856T2 (en) 2006-10-19
EP1256587A4 (en) 2004-01-28
ES2261224T3 (en) 2006-11-16
DK1489090T3 (en) 2006-05-22
DE60025856D1 (en) 2006-04-13
KR20040074096A (en) 2004-08-21
EP1489090A1 (en) 2004-12-22
ATE321770T1 (en) 2006-04-15
EP1256587A1 (en) 2002-11-13
CA2386828A1 (en) 2002-02-21
KR20040066185A (en) 2004-07-23
KR20040066186A (en) 2004-07-23
US6734292B1 (en) 2004-05-11
DE60027015D1 (en) 2006-05-18
KR20040066187A (en) 2004-07-23
ATE316977T1 (en) 2006-02-15
ES2257720T3 (en) 2006-08-01
PT1489090E (en) 2006-05-31
DE60027015T2 (en) 2006-10-05
CA2386828C (en) 2006-01-24
EP1256587B1 (en) 2006-03-29
KR20040066184A (en) 2004-07-23

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