ATE332892T1 - Zwischenverbindung für die herstellung von carvedilol - Google Patents
Zwischenverbindung für die herstellung von carvedilolInfo
- Publication number
- ATE332892T1 ATE332892T1 AT03077684T AT03077684T ATE332892T1 AT E332892 T1 ATE332892 T1 AT E332892T1 AT 03077684 T AT03077684 T AT 03077684T AT 03077684 T AT03077684 T AT 03077684T AT E332892 T1 ATE332892 T1 AT E332892T1
- Authority
- AT
- Austria
- Prior art keywords
- carvedilol
- production
- intermediate compound
- new intermediate
- reacgents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
- C07D263/20—Oxygen atoms attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/04—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups from amines with formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/96—Esters of carbonic or haloformic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK200000801A DK174645B1 (da) | 2000-05-18 | 2000-05-18 | Fremgangsmåde og mellemprodukter til fremstillingen af 1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxy-phenoxy)-ethylamino]-propan-2-ol, carvedilol og syreadditionssalte deraf |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE332892T1 true ATE332892T1 (de) | 2006-08-15 |
Family
ID=8159503
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03077684T ATE332892T1 (de) | 2000-05-18 | 2001-05-03 | Zwischenverbindung für die herstellung von carvedilol |
| AT03077677T ATE322481T1 (de) | 2000-05-18 | 2001-05-03 | Zwischenverbindung zur herstellung von carvedilol |
| AT01929337T ATE258165T1 (de) | 2000-05-18 | 2001-05-03 | Verfahren und zwischenverbindungen zur herstellung von 1-(9h-carbazol-4-yloxy)-3-(2-(2- methoxy-phenoxy)-ethylamino)-propan-2-ol, carvediol, oder ein säureadditionssalz davon |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03077677T ATE322481T1 (de) | 2000-05-18 | 2001-05-03 | Zwischenverbindung zur herstellung von carvedilol |
| AT01929337T ATE258165T1 (de) | 2000-05-18 | 2001-05-03 | Verfahren und zwischenverbindungen zur herstellung von 1-(9h-carbazol-4-yloxy)-3-(2-(2- methoxy-phenoxy)-ethylamino)-propan-2-ol, carvediol, oder ein säureadditionssalz davon |
Country Status (8)
| Country | Link |
|---|---|
| EP (3) | EP1282601B1 (de) |
| AT (3) | ATE332892T1 (de) |
| CA (1) | CA2407103A1 (de) |
| DK (4) | DK174645B1 (de) |
| ES (3) | ES2214414T3 (de) |
| NO (1) | NO323828B1 (de) |
| PT (3) | PT1367052E (de) |
| WO (1) | WO2001087837A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050261355A1 (en) | 2002-06-27 | 2005-11-24 | Sb Pharmco Puerto Rico Inc., | Carvedilol hydobromide |
| KR20110134952A (ko) * | 2002-06-27 | 2011-12-15 | 스미스클라인 비이참 (코르크) 리미티드 | 카베딜롤 인산염 및(또는) 그의 용매화물, 상응하는 조성물, 및(또는) 치료 방법 |
| EP1615888A1 (de) | 2003-04-21 | 2006-01-18 | Matrix Laboratories Ltd | Verfahren zur herstellung von carvedilol form-ii |
| US7750036B2 (en) | 2003-11-25 | 2010-07-06 | Sb Pharmco Puerto Rico Inc. | Carvedilol salts, corresponding compositions, methods of delivery and/or treatment |
| KR100746455B1 (ko) * | 2006-02-23 | 2007-08-03 | 안국약품 주식회사 | 고광학순도의 키랄 카베딜롤의 제조방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3152168A (en) * | 1961-09-05 | 1964-10-06 | Monsanto Co | Haloalkyl pentahalophenyl carbonates |
| DE2815926A1 (de) * | 1978-04-13 | 1979-10-18 | Boehringer Mannheim Gmbh | Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| FR2506769A2 (fr) * | 1978-06-09 | 1982-12-03 | Delalande Sa | Para-((cyano-5 n pentyl-1) phenyl)-3 methoxymethyl-5 oxazolidinone-2, son procede de preparation et ses applications en therapeutique |
| HU227441B1 (en) * | 1997-11-24 | 2011-06-28 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | Process for producing carvedilol, enantiomers and salts thereof |
-
2000
- 2000-05-18 DK DK200000801A patent/DK174645B1/da not_active IP Right Cessation
-
2001
- 2001-05-03 EP EP01929337A patent/EP1282601B1/de not_active Expired - Lifetime
- 2001-05-03 ES ES01929337T patent/ES2214414T3/es not_active Expired - Lifetime
- 2001-05-03 AT AT03077684T patent/ATE332892T1/de not_active IP Right Cessation
- 2001-05-03 CA CA002407103A patent/CA2407103A1/en not_active Abandoned
- 2001-05-03 PT PT03077684T patent/PT1367052E/pt unknown
- 2001-05-03 EP EP03077677A patent/EP1375474B1/de not_active Expired - Lifetime
- 2001-05-03 PT PT03077677T patent/PT1375474E/pt unknown
- 2001-05-03 ES ES03077684T patent/ES2268275T3/es not_active Expired - Lifetime
- 2001-05-03 DK DK03077677T patent/DK1375474T3/da active
- 2001-05-03 EP EP03077684A patent/EP1367052B1/de not_active Expired - Lifetime
- 2001-05-03 ES ES03077677T patent/ES2260575T3/es not_active Expired - Lifetime
- 2001-05-03 DK DK03077684T patent/DK1367052T3/da active
- 2001-05-03 DK DK01929337T patent/DK1282601T3/da active
- 2001-05-03 PT PT01929337T patent/PT1282601E/pt unknown
- 2001-05-03 AT AT03077677T patent/ATE322481T1/de not_active IP Right Cessation
- 2001-05-03 AT AT01929337T patent/ATE258165T1/de not_active IP Right Cessation
- 2001-05-03 WO PCT/DK2001/000306 patent/WO2001087837A1/en active IP Right Grant
-
2002
- 2002-11-15 NO NO20025476A patent/NO323828B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK174645B1 (da) | 2003-08-04 |
| ATE322481T1 (de) | 2006-04-15 |
| PT1282601E (pt) | 2004-06-30 |
| NO20025476D0 (no) | 2002-11-15 |
| ATE258165T1 (de) | 2004-02-15 |
| ES2214414T3 (es) | 2004-09-16 |
| DK1367052T3 (da) | 2006-09-25 |
| EP1367052B1 (de) | 2006-07-12 |
| PT1375474E (pt) | 2006-07-31 |
| DK200000801A (da) | 2001-11-19 |
| DK1375474T3 (da) | 2006-08-07 |
| NO20025476L (no) | 2002-11-15 |
| EP1282601A1 (de) | 2003-02-12 |
| EP1282601B1 (de) | 2004-01-21 |
| CA2407103A1 (en) | 2001-11-22 |
| EP1375474B1 (de) | 2006-04-05 |
| DK1282601T3 (da) | 2004-05-24 |
| WO2001087837A1 (en) | 2001-11-22 |
| PT1367052E (pt) | 2006-10-31 |
| EP1367052A3 (de) | 2003-12-10 |
| NO323828B1 (no) | 2007-07-09 |
| ES2268275T3 (es) | 2007-03-16 |
| ES2260575T3 (es) | 2006-11-01 |
| EP1375474A3 (de) | 2004-10-06 |
| EP1367052A2 (de) | 2003-12-03 |
| EP1375474A2 (de) | 2004-01-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1367052 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |