DE69806189D1 - Acronycinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen - Google Patents
Acronycinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungenInfo
- Publication number
- DE69806189D1 DE69806189D1 DE69806189T DE69806189T DE69806189D1 DE 69806189 D1 DE69806189 D1 DE 69806189D1 DE 69806189 T DE69806189 T DE 69806189T DE 69806189 T DE69806189 T DE 69806189T DE 69806189 D1 DE69806189 D1 DE 69806189D1
- Authority
- DE
- Germany
- Prior art keywords
- alkyl
- acronycine
- derivatives
- production
- pharmaceutical preparations
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SMPZPKRDRQOOHT-UHFFFAOYSA-N acronycine Chemical class CN1C2=CC=CC=C2C(=O)C2=C1C(C=CC(C)(C)O1)=C1C=C2OC SMPZPKRDRQOOHT-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000002431 hydrogen Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- -1 hydroxy, mercapto Chemical class 0.000 abstract 2
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004385 trihaloalkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9716131A FR2772765B1 (fr) | 1997-12-19 | 1997-12-19 | Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| PCT/FR1998/002785 WO1999032491A1 (fr) | 1997-12-19 | 1998-12-18 | Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69806189D1 true DE69806189D1 (de) | 2002-07-25 |
| DE69806189T2 DE69806189T2 (de) | 2003-02-13 |
Family
ID=9514822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69806189T Expired - Lifetime DE69806189T2 (de) | 1997-12-19 | 1998-12-18 | Acronycinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6288073B1 (de) |
| EP (1) | EP1042326B1 (de) |
| JP (1) | JP3825630B2 (de) |
| CN (1) | CN1109686C (de) |
| AT (1) | ATE219491T1 (de) |
| AU (1) | AU738322B2 (de) |
| BR (1) | BR9813756A (de) |
| CA (1) | CA2315909C (de) |
| DE (1) | DE69806189T2 (de) |
| DK (1) | DK1042326T3 (de) |
| ES (1) | ES2179548T3 (de) |
| FR (1) | FR2772765B1 (de) |
| HK (1) | HK1033131A1 (de) |
| HU (1) | HUP0100342A3 (de) |
| NO (1) | NO20003106L (de) |
| NZ (1) | NZ504833A (de) |
| PL (1) | PL192814B1 (de) |
| PT (1) | PT1042326E (de) |
| WO (1) | WO1999032491A1 (de) |
| ZA (1) | ZA9811645B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2795071B1 (fr) * | 1999-06-16 | 2001-07-27 | Adir | Nouveaux derives de carboxylate de 7-oxo-2,3,7,14- tetrahydro-1h-benzo[b]pyrano[3,2,h] acridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US7056929B2 (en) * | 2001-07-25 | 2006-06-06 | Les Laboratoires Servier | Benzo[b]pyrano[3,2-h]acridin-7-one compounds |
| FR2827864B1 (fr) * | 2001-07-25 | 2005-09-16 | Servier Lab | Nouveaux derives de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2856687B1 (fr) * | 2003-06-25 | 2005-09-16 | Servier Lab | Nouveaux derives de benzo[a]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2865734B1 (fr) * | 2004-02-03 | 2006-05-19 | Servier Lab | NOUVAEUX DERIVES DE BENZO[b]CHROMENO-NAPHTHYRIDIN-7-ONE ET DE PYRANO[2'3':7,8]QUINO[2,3-b]QUINOXALIN-7-ONE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT |
| FR2879600B1 (fr) * | 2004-12-22 | 2007-02-09 | Servier Lab | Nouveaux derives cinnamates de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| JP4392502B2 (ja) * | 2005-06-10 | 2010-01-06 | 国立大学法人 岡山大学 | 蛍光性アミノ酸誘導体 |
| US11784731B2 (en) * | 2021-03-09 | 2023-10-10 | Apple Inc. | Multi-phase-level signaling to improve data bandwidth over lossy channels |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2716197B1 (fr) * | 1994-02-17 | 1996-04-19 | Adir | Nouveaux analogues de l'acronycine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
-
1997
- 1997-12-19 FR FR9716131A patent/FR2772765B1/fr not_active Expired - Fee Related
-
1998
- 1998-12-18 ZA ZA9811645A patent/ZA9811645B/xx unknown
- 1998-12-18 ES ES98962511T patent/ES2179548T3/es not_active Expired - Lifetime
- 1998-12-18 WO PCT/FR1998/002785 patent/WO1999032491A1/fr active IP Right Grant
- 1998-12-18 AT AT98962511T patent/ATE219491T1/de not_active IP Right Cessation
- 1998-12-18 JP JP2000525428A patent/JP3825630B2/ja not_active Expired - Fee Related
- 1998-12-18 US US09/581,853 patent/US6288073B1/en not_active Expired - Fee Related
- 1998-12-18 PT PT98962511T patent/PT1042326E/pt unknown
- 1998-12-18 CA CA002315909A patent/CA2315909C/fr not_active Expired - Fee Related
- 1998-12-18 AU AU17663/99A patent/AU738322B2/en not_active Ceased
- 1998-12-18 HU HU0100342A patent/HUP0100342A3/hu unknown
- 1998-12-18 DE DE69806189T patent/DE69806189T2/de not_active Expired - Lifetime
- 1998-12-18 BR BR9813756-5A patent/BR9813756A/pt not_active Application Discontinuation
- 1998-12-18 EP EP98962511A patent/EP1042326B1/de not_active Expired - Lifetime
- 1998-12-18 PL PL341281A patent/PL192814B1/pl not_active IP Right Cessation
- 1998-12-18 DK DK98962511T patent/DK1042326T3/da active
- 1998-12-18 CN CN98812425A patent/CN1109686C/zh not_active Expired - Fee Related
- 1998-12-18 NZ NZ504833A patent/NZ504833A/en unknown
-
2000
- 2000-06-16 NO NO20003106A patent/NO20003106L/no not_active Application Discontinuation
-
2001
- 2001-06-01 HK HK01103792A patent/HK1033131A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT1042326E (pt) | 2002-10-31 |
| CN1109686C (zh) | 2003-05-28 |
| ES2179548T3 (es) | 2003-01-16 |
| JP2001526290A (ja) | 2001-12-18 |
| NZ504833A (en) | 2001-11-30 |
| PL341281A1 (en) | 2001-04-09 |
| JP3825630B2 (ja) | 2006-09-27 |
| FR2772765A1 (fr) | 1999-06-25 |
| NO20003106L (no) | 2000-08-16 |
| US6288073B1 (en) | 2001-09-11 |
| CN1282332A (zh) | 2001-01-31 |
| HUP0100342A3 (en) | 2003-04-28 |
| ZA9811645B (en) | 1999-06-24 |
| NO20003106D0 (no) | 2000-06-16 |
| AU1766399A (en) | 1999-07-12 |
| ATE219491T1 (de) | 2002-07-15 |
| WO1999032491A1 (fr) | 1999-07-01 |
| PL192814B1 (pl) | 2006-12-29 |
| BR9813756A (pt) | 2000-10-03 |
| DE69806189T2 (de) | 2003-02-13 |
| HK1033131A1 (en) | 2001-08-17 |
| AU738322B2 (en) | 2001-09-13 |
| HUP0100342A2 (hu) | 2001-09-28 |
| CA2315909C (fr) | 2007-01-02 |
| EP1042326A1 (de) | 2000-10-11 |
| FR2772765B1 (fr) | 2000-03-17 |
| EP1042326B1 (de) | 2002-06-19 |
| DK1042326T3 (da) | 2002-09-23 |
| CA2315909A1 (fr) | 1999-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |