DE69105786D1 - Harnstoffderivate, deren Herstellung sowie diese enthaltende pharmazeutische Zusammensetzungen. - Google Patents

Harnstoffderivate, deren Herstellung sowie diese enthaltende pharmazeutische Zusammensetzungen.

Info

Publication number
DE69105786D1
DE69105786D1 DE69105786T DE69105786T DE69105786D1 DE 69105786 D1 DE69105786 D1 DE 69105786D1 DE 69105786 T DE69105786 T DE 69105786T DE 69105786 T DE69105786 T DE 69105786T DE 69105786 D1 DE69105786 D1 DE 69105786D1
Authority
DE
Germany
Prior art keywords
urea derivatives
pharmaceutical compositions
compositions containing
preparation
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69105786T
Other languages
English (en)
Other versions
DE69105786T2 (de
Inventor
Noriki Ito
Koyo Matsuda
Kiyoshi Iwaoka
Yuichi Iizumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69105786D1 publication Critical patent/DE69105786D1/de
Publication of DE69105786T2 publication Critical patent/DE69105786T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/26—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/18—Systems containing only non-condensed rings with a ring being at least seven-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
    • C07C2603/26—Phenanthrenes; Hydrogenated phenanthrenes
DE69105786T 1990-03-12 1991-03-06 Harnstoffderivate, deren Herstellung sowie diese enthaltende pharmazeutische Zusammensetzungen. Expired - Fee Related DE69105786T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6075490 1990-03-12

Publications (2)

Publication Number Publication Date
DE69105786D1 true DE69105786D1 (de) 1995-01-26
DE69105786T2 DE69105786T2 (de) 1995-04-27

Family

ID=13151377

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69105786T Expired - Fee Related DE69105786T2 (de) 1990-03-12 1991-03-06 Harnstoffderivate, deren Herstellung sowie diese enthaltende pharmazeutische Zusammensetzungen.

Country Status (14)

Country Link
EP (1) EP0447116B1 (de)
JP (1) JPH04234839A (de)
KR (1) KR910016689A (de)
CN (1) CN1024790C (de)
AT (1) ATE115558T1 (de)
AU (1) AU643759B2 (de)
CA (1) CA2037669A1 (de)
DE (1) DE69105786T2 (de)
DK (1) DK0447116T3 (de)
ES (1) ES2068497T3 (de)
FI (1) FI911189A (de)
GR (1) GR3015149T3 (de)
HU (1) HUT57712A (de)
IE (1) IE910780A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU632809B2 (en) * 1989-05-25 1993-01-14 Takeda Chemical Industries Ltd. Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof
RU94046149A (ru) * 1992-05-28 1996-11-27 Пфайзер Инк. (US) Новые n-арил и n-гетероарил производные мочевины как ингибиторы ацил кофермента а:холестерин ацил трансферазы (асат) фармацевтическая композиция, способ ингибирования (асат)
US5401758A (en) * 1993-10-07 1995-03-28 Bristol-Myers Squibb Company Pyridinyl cyanoguanidine compounds
DE4401893A1 (de) * 1994-01-24 1995-07-27 Bayer Ag Substituierte Arylharnstoffe
EP0742208A1 (de) * 1995-05-05 1996-11-13 Grelan Pharmaceutical Co., Ltd. 2-Ureido-benzamid-Derivate
EP0866059B1 (de) 1995-10-05 2001-12-05 Kyoto Pharmaceutical Industries, Ltd. Neue heterozyklische derivate und ihre medizinische anwendung
US5866609A (en) * 1996-08-09 1999-02-02 Ss Pharmaceutical Co., Ltd. Substituted vinylurea derivatives and medicine containing the same
US8349853B2 (en) 2001-09-05 2013-01-08 Minerva Biotechnologies Corporation Compositions and methods of treatment of cancer
FR2831166B1 (fr) * 2001-10-18 2004-02-27 Sanofi Synthelabo Aralkyl-tetrahydro-pyridines, leur preparation et compositions pharmaceutiques les contenant
AU2003252638B8 (en) 2002-07-17 2009-03-05 Kyoto Pharmaceutical Industries, Ltd. Novel indoline compound and medicinal use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2928485A1 (de) * 1979-07-14 1981-01-29 Bayer Ag Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
US4473579A (en) * 1982-01-26 1984-09-25 American Cyanamid Company Antiatherosclerotic tetrasubstituted ureas and thioureas
JPS58222063A (ja) * 1982-06-17 1983-12-23 Nippon Tokushu Noyaku Seizo Kk ベンジルウレア誘導体、その製法及び農園芸用殺菌剤
US4868210A (en) * 1988-03-30 1989-09-19 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic compounds and compositions
AU632809B2 (en) * 1989-05-25 1993-01-14 Takeda Chemical Industries Ltd. Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof

Also Published As

Publication number Publication date
CN1054766A (zh) 1991-09-25
ATE115558T1 (de) 1994-12-15
AU643759B2 (en) 1993-11-25
CA2037669A1 (en) 1991-09-13
AU7276291A (en) 1991-09-12
JPH04234839A (ja) 1992-08-24
EP0447116A1 (de) 1991-09-18
IE910780A1 (en) 1991-09-25
FI911189A (fi) 1991-09-13
ES2068497T3 (es) 1995-04-16
HU910784D0 (en) 1991-09-30
CN1024790C (zh) 1994-06-01
DE69105786T2 (de) 1995-04-27
GR3015149T3 (en) 1995-05-31
KR910016689A (ko) 1991-11-05
EP0447116B1 (de) 1994-12-14
DK0447116T3 (da) 1995-05-15
HUT57712A (en) 1991-12-30
FI911189A0 (fi) 1991-03-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee