DE69802615D1 - Triaromatische Verbindungen, diese enthaltende Zusammensetzungen sowie ihre Anwendungen - Google Patents
Triaromatische Verbindungen, diese enthaltende Zusammensetzungen sowie ihre AnwendungenInfo
- Publication number
- DE69802615D1 DE69802615D1 DE69802615T DE69802615T DE69802615D1 DE 69802615 D1 DE69802615 D1 DE 69802615D1 DE 69802615 T DE69802615 T DE 69802615T DE 69802615 T DE69802615 T DE 69802615T DE 69802615 D1 DE69802615 D1 DE 69802615D1
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- DE
- Germany
- Prior art keywords
- compositions containing
- triaromatic compounds
- triaromatic
- compounds
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyridine Compounds (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9706340A FR2763588B1 (fr) | 1997-05-23 | 1997-05-23 | Composes triaromatiques, compositions les contenant et utilisations |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69802615D1 true DE69802615D1 (de) | 2002-01-10 |
DE69802615T2 DE69802615T2 (de) | 2002-05-16 |
Family
ID=9507187
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69802615T Expired - Lifetime DE69802615T2 (de) | 1997-05-23 | 1998-05-13 | Triaromatische Verbindungen, diese enthaltende Zusammensetzungen sowie ihre Anwendungen |
Country Status (21)
Country | Link |
---|---|
US (1) | US6150413A (de) |
EP (1) | EP0879814B1 (de) |
JP (1) | JP2974658B2 (de) |
KR (1) | KR100280238B1 (de) |
AR (1) | AR011746A1 (de) |
AT (1) | ATE209622T1 (de) |
AU (1) | AU713781B2 (de) |
BR (1) | BR9802130A (de) |
CA (1) | CA2238465C (de) |
DE (1) | DE69802615T2 (de) |
DK (1) | DK0879814T3 (de) |
ES (1) | ES2170460T3 (de) |
FR (1) | FR2763588B1 (de) |
HU (1) | HUP9801167A3 (de) |
IL (1) | IL124565A0 (de) |
NO (1) | NO310973B1 (de) |
NZ (1) | NZ330453A (de) |
PL (1) | PL193040B1 (de) |
PT (1) | PT879814E (de) |
RU (1) | RU2149863C1 (de) |
ZA (1) | ZA984296B (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6956049B1 (en) * | 1999-08-31 | 2005-10-18 | Merck & Co., Inc. | Methods of modulating processes mediated by excitatory amino acid receptors |
FR2801305B1 (fr) * | 1999-11-24 | 2002-12-06 | Galderma Res & Dev | Analogues de la vitamine d |
US6569901B2 (en) | 2000-01-28 | 2003-05-27 | Novo Nordisk A/S | Alkynyl-substituted propionic acid derivatives, their preparation and use |
FR2804323B1 (fr) * | 2000-01-31 | 2006-07-07 | Galderma Res & Dev | Utilisation de composes de type retinoides en tant qu'agents anti-bacteriens |
WO2003059378A2 (en) * | 2001-12-29 | 2003-07-24 | Novo Nordisk A/S | Combined use of a glp-1 compound and another drug for treating dyslipidemia |
DE60309480T2 (de) * | 2002-08-27 | 2007-05-10 | Galderma Research & Development, S.N.C. | Vitamin d-analoge |
JP2006513996A (ja) * | 2002-10-24 | 2006-04-27 | メルク エンド カムパニー インコーポレーテッド | 代謝調節型グルタミン酸受容体結合用トレーサーとしてのアルキン誘導体 |
SE0301010D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
SA04250253B1 (ar) * | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
FR2861068B1 (fr) * | 2003-10-17 | 2005-12-23 | Galderma Res & Dev | Nouveaux procedes de preparation de l'acide 4-[4-(4-methoxymethoxy-4'-methylbiphenyl-2-yl)-but-3ene-(e)- 1-ynyl]-benzoique |
GB0415320D0 (en) * | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
GB0418830D0 (en) * | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
WO2006056752A1 (en) * | 2004-11-23 | 2006-06-01 | Astrazeneca Ab | Phenoxyacetic acid derivatives useful for treating respiratory diseases |
FR2880020B1 (fr) * | 2004-12-23 | 2007-02-16 | Galderma Res & Dev | NOUVEAUX LIGANDS MODULATEURS DES RECEPTEURS RARs, UTILISATION EN MEDECINE HUMAINE AINSI QU'EN COSMETIQUE |
AU2005318292B2 (en) * | 2004-12-23 | 2011-09-22 | Galderma Research & Development | Novel ligands that modulate RAR receptors, and use thereof in human medicine and in cosmetics |
JP5155171B2 (ja) | 2005-10-06 | 2013-02-27 | アストラゼネカ・アクチエボラーグ | 新規化合物 |
TW200745003A (en) | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
JP2009514935A (ja) * | 2005-11-05 | 2009-04-09 | アストラゼネカ・アクチエボラーグ | 新規化合物 |
US20080293775A1 (en) * | 2005-12-15 | 2008-11-27 | Astrazeneca Ab | Substituted Diphenylethers, -Amines, -Sulfides and -Methanes for the Treatment of Respiratory Disease |
FR2910321B1 (fr) | 2006-12-21 | 2009-07-10 | Galderma Res & Dev S N C Snc | Gel creme comprenant au moins un retinoide et du peroxyde de benzole |
FR2910320B1 (fr) | 2006-12-21 | 2009-02-13 | Galderma Res & Dev S N C Snc | Emulsion comprenant au moins un retinoide et du peroxyde de benzole |
UA100983C2 (ru) * | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
FR2931661B1 (fr) | 2008-05-30 | 2010-07-30 | Galderma Res & Dev | Nouvelles compositions depigmentantes sous forme d'une composition anhydre sans vaseline et sans elastomere comprenant un derive phenolique solubilise et un retinoide. |
FR2996845A1 (fr) * | 2012-10-12 | 2014-04-18 | Servier Lab | Nouveau procede de synthese du 3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
RU2017125663A (ru) | 2014-12-19 | 2019-01-21 | Галдерма Ресерч Энд Девелопмент | Новые соединения, способ их синтеза и их применение в медицине, а также в косметике |
WO2018177993A1 (de) | 2017-03-31 | 2018-10-04 | Bayer Cropscience Aktiengesellschaft | Pyrazole zur bekämpfung von arthropoden |
EP3762368B1 (de) | 2018-03-08 | 2022-01-26 | Incyte Corporation | Aminopyrazindiolverbindungen als pi3k-y-hemmer |
US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
JP2022550432A (ja) | 2019-10-02 | 2022-12-01 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 大動脈弁の石灰化を後退、予防、又は遅延させるためのレチノイン酸受容体(rar)アゴニストの使用 |
TW202342425A (zh) | 2022-02-28 | 2023-11-01 | 日商安斯泰來製藥股份有限公司 | 芳基炔醯胺衍生物 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61271262A (ja) * | 1985-05-24 | 1986-12-01 | Hisamitsu Pharmaceut Co Inc | フエニルアルカン酸誘導体 |
US5466861A (en) * | 1992-11-25 | 1995-11-14 | Sri International | Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors |
FR2719044B1 (fr) * | 1994-04-26 | 1996-05-31 | Cird Galderma | Nouveaux composés bi-aromatiques acétylénés à groupement adamantyle, compositions pharmaceutiques et cosmétiques les contenant et utilisations. |
US5968908A (en) * | 1994-12-19 | 1999-10-19 | American Cyanamid Company | Restricted 9-cis retinoids |
FR2741876B1 (fr) * | 1995-12-01 | 1998-01-09 | Cird Galderma | Composes biaromatiques portant un groupement adamantyl en para, compositions pharmaceutiques et cosmetiques les contenant et utilisations |
FR2741878B1 (fr) * | 1995-12-01 | 1998-01-09 | Cird Galderma | Composes biaromatiques portant un groupement adamantyl en ortho, compositions pharmaceutiques et cosmetiques les contenant et utilisations |
US5760276A (en) * | 1997-03-06 | 1998-06-02 | Allergan | Aryl-and heteroarylcyclohexenyl substituted alkenes having retinoid agonist, antagonist or inverse agonist type biological activity |
US5998654A (en) * | 1997-07-25 | 1999-12-07 | Ligand Pharmaceuticals Incorporated | Retinoic acid receptor antagonist compounds and methods |
-
1997
- 1997-05-23 FR FR9706340A patent/FR2763588B1/fr not_active Expired - Fee Related
-
1998
- 1998-05-13 ES ES98401144T patent/ES2170460T3/es not_active Expired - Lifetime
- 1998-05-13 DE DE69802615T patent/DE69802615T2/de not_active Expired - Lifetime
- 1998-05-13 EP EP98401144A patent/EP0879814B1/de not_active Expired - Lifetime
- 1998-05-13 DK DK98401144T patent/DK0879814T3/da active
- 1998-05-13 PT PT98401144T patent/PT879814E/pt unknown
- 1998-05-13 AT AT98401144T patent/ATE209622T1/de active
- 1998-05-18 NZ NZ330453A patent/NZ330453A/xx unknown
- 1998-05-19 AU AU67049/98A patent/AU713781B2/en not_active Ceased
- 1998-05-20 IL IL12456598A patent/IL124565A0/xx not_active IP Right Cessation
- 1998-05-20 NO NO19982296A patent/NO310973B1/no unknown
- 1998-05-21 ZA ZA984296A patent/ZA984296B/xx unknown
- 1998-05-22 RU RU98109793A patent/RU2149863C1/ru not_active IP Right Cessation
- 1998-05-22 CA CA002238465A patent/CA2238465C/fr not_active Expired - Fee Related
- 1998-05-22 AR ARP980102376A patent/AR011746A1/es active IP Right Grant
- 1998-05-22 HU HU9801167A patent/HUP9801167A3/hu unknown
- 1998-05-22 PL PL326443A patent/PL193040B1/pl not_active IP Right Cessation
- 1998-05-22 JP JP10141929A patent/JP2974658B2/ja not_active Expired - Fee Related
- 1998-05-23 KR KR1019980018678A patent/KR100280238B1/ko not_active IP Right Cessation
- 1998-05-25 BR BR9802130A patent/BR9802130A/pt not_active Application Discontinuation
- 1998-05-26 US US09/084,235 patent/US6150413A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ZA984296B (en) | 1998-11-26 |
EP0879814B1 (de) | 2001-11-28 |
EP0879814A1 (de) | 1998-11-25 |
FR2763588A1 (fr) | 1998-11-27 |
CA2238465A1 (fr) | 1998-11-23 |
AU6704998A (en) | 1998-11-26 |
HUP9801167A2 (hu) | 1998-12-28 |
RU2149863C1 (ru) | 2000-05-27 |
PL326443A1 (en) | 1998-12-07 |
DE69802615T2 (de) | 2002-05-16 |
KR19980087317A (ko) | 1998-12-05 |
PT879814E (pt) | 2002-05-31 |
NO310973B1 (no) | 2001-09-24 |
US6150413A (en) | 2000-11-21 |
NZ330453A (en) | 1999-05-28 |
AR011746A1 (es) | 2000-08-30 |
JPH1129522A (ja) | 1999-02-02 |
DK0879814T3 (da) | 2002-02-25 |
FR2763588B1 (fr) | 1999-07-09 |
HUP9801167A3 (en) | 2000-03-28 |
JP2974658B2 (ja) | 1999-11-10 |
ES2170460T3 (es) | 2002-08-01 |
PL193040B1 (pl) | 2007-01-31 |
ATE209622T1 (de) | 2001-12-15 |
AU713781B2 (en) | 1999-12-09 |
CA2238465C (fr) | 2003-07-15 |
BR9802130A (pt) | 1999-07-20 |
NO982296L (no) | 1998-11-24 |
NO982296D0 (no) | 1998-05-20 |
HU9801167D0 (en) | 1998-07-28 |
KR100280238B1 (ko) | 2001-02-01 |
IL124565A0 (en) | 1998-12-06 |
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Owner name: GALDERMA RESEARCH & DEVELOPMENT, BIOT, FR |