DE69739174D1 - Tolerogenefragmente aus natürlichen allergenen - Google Patents

Tolerogenefragmente aus natürlichen allergenen

Info

Publication number
DE69739174D1
DE69739174D1 DE69739174T DE69739174T DE69739174D1 DE 69739174 D1 DE69739174 D1 DE 69739174D1 DE 69739174 T DE69739174 T DE 69739174T DE 69739174 T DE69739174 T DE 69739174T DE 69739174 D1 DE69739174 D1 DE 69739174D1
Authority
DE
Germany
Prior art keywords
fragments
relates
tolerogene
allergens
natural
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69739174T
Other languages
English (en)
Inventor
Lubertus Berrens
Romano Maria Leticia Gonzales
Camara Maria Teresa Gallego
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorios Leti SA
Original Assignee
Laboratorios Leti SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Leti SA filed Critical Laboratorios Leti SA
Application granted granted Critical
Publication of DE69739174D1 publication Critical patent/DE69739174D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43527Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from ticks
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • A61K39/36Allergens from pollen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Water Supply & Treatment (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69739174T 1997-10-30 1997-10-30 Tolerogenefragmente aus natürlichen allergenen Expired - Lifetime DE69739174D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/NL1997/000598 WO1999022762A1 (en) 1997-10-30 1997-10-30 Tolerogenic fragments of natural allergens

Publications (1)

Publication Number Publication Date
DE69739174D1 true DE69739174D1 (de) 2009-01-29

Family

ID=19866218

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69739174T Expired - Lifetime DE69739174D1 (de) 1997-10-30 1997-10-30 Tolerogenefragmente aus natürlichen allergenen

Country Status (16)

Country Link
US (2) US6350590B1 (de)
EP (2) EP2042192A3 (de)
JP (1) JP3790099B2 (de)
AT (1) ATE417626T1 (de)
AU (1) AU729589C (de)
BR (1) BR9714899A (de)
CA (1) CA2307655C (de)
CZ (1) CZ302352B6 (de)
DE (1) DE69739174D1 (de)
DK (1) DK1024829T3 (de)
ES (1) ES2319341T3 (de)
HU (1) HUP0004831A3 (de)
IL (1) IL135881A0 (de)
PL (1) PL187544B1 (de)
PT (1) PT1024829E (de)
WO (1) WO1999022762A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9714899A (pt) * 1997-10-30 2000-08-22 C B F Letti S A Processo para produzir um extrato provendo tolerância para aplicação a um indivìduo a fim de prover tolerância contra material alergênico, extrato de material de fonte alergênica, preparação, e,uso da mesma
CA2471735A1 (en) * 2001-08-29 2003-03-13 Kyogo Itoh Desensitizers
EP1872792A1 (de) * 2006-06-29 2008-01-02 Biotech Tools S.A. Methode zur Herstellung eines hydrolysierten Allergens
US20100278880A1 (en) * 2008-01-02 2010-11-04 Biotech Tools S.A. Pharmaceutical formulation for allergen preparation
WO2012149393A2 (en) 2011-04-29 2012-11-01 Selecta Biosciences, Inc. Tolerogenic synthetic nanocarriers for antigen-specific deletion of t effector cells
KR20240119156A (ko) 2013-05-03 2024-08-06 셀렉타 바이오사이언시즈, 인크. 제i형 및 제iv형 과민성을 감소시키기 위한 관용유발 합성 나노담체의 국부, 병용 투여
AU2015311708A1 (en) 2014-09-07 2017-02-02 Selecta Biosciences, Inc. Methods and compositions for attenuating exon skipping anti-viral transfer vector immune responses
BR112019006844A2 (pt) 2016-10-05 2019-06-25 Asit Biotech S A prevenção de alergia
EP3592389A1 (de) 2017-03-11 2020-01-15 Selecta Biosciences, Inc. Verfahren und zusammensetzungen in zusammenhang mit einer kombinierten behandlung mit entzündungshemmenden mitteln und synthetischen nanoträgern mit einem immunsuppressivum

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US150389A (en) 1874-05-05 Improvement in combined paper-clips and letter-folders
GB1282163A (en) 1969-08-06 1972-07-19 Beecham Group Ltd Modified allergens and a process for their preparation
GB1492973A (en) 1974-02-16 1977-11-23 Beecham Group Ltd Process for preparing injectable compositions
GB1578348A (en) 1976-08-17 1980-11-05 Pharmacia Ab Products and a method for the therapeutic suppression of reaginic antibodies responsible for common allergic
US4338297A (en) 1980-02-19 1982-07-06 Michael Jacob G Polypeptide active pollen immunosuppressant fraction
DE3160926D1 (en) 1980-04-15 1983-10-27 Beecham Group Plc Allergens modified with polysarcosines
JPS58115120A (ja) 1981-12-28 1983-07-08 Nippon Oil Co Ltd ピツチ系炭素繊維の製造方法
ES2013359A6 (es) 1988-11-04 1990-05-01 Corporacion Biolog Farmaceutic Procedimiento para la fabricacion de alergenos inmunogenicos polimerizados.
NL8900652A (nl) 1989-03-16 1990-10-16 Leti Lab Primair-toxische stoffen of allergenen, isoleerbaar uit plantaardig materiaal, alsmede werkwijzen ter bereiding ervan en de toepassing ervan.
US5792506A (en) * 1991-10-12 1998-08-11 The Regents Of The University Of California Neutralization of food allergens by thioredoxin
ATE148708T1 (de) * 1992-09-21 1997-02-15 Leti Lab Verfahren zur reinigung von waessrigen extrakten, die allergenische proteine enthalten, so erhaltene extrakte und ihre verwendung
WO1994006821A1 (en) 1992-09-21 1994-03-31 Laboratorios Leti S.A. A process for the purification of aqueous extracts containing allergenically active proteins, extracts obtainable according to this process as well as their use
MX9704137A (es) * 1994-12-07 1997-09-30 Novo Nordisk As Polipeptidos de alergenicidad reducida.
CZ283615B6 (cs) * 1996-05-31 1998-05-13 Bioveta, A.S. Způsob výroby vakcín proti dermatofytózám zvířat a dermatofytických alergenů
BR9714899A (pt) * 1997-10-30 2000-08-22 C B F Letti S A Processo para produzir um extrato provendo tolerância para aplicação a um indivìduo a fim de prover tolerância contra material alergênico, extrato de material de fonte alergênica, preparação, e,uso da mesma
WO2004031961A1 (en) 2002-09-30 2004-04-15 Insignia Solutions Plc Efficient system and method for updating a memory device

Also Published As

Publication number Publication date
AU5883398A (en) 1999-05-24
PL340293A1 (en) 2001-01-29
HUP0004831A2 (hu) 2001-05-28
AU729589B2 (en) 2001-02-08
CA2307655A1 (en) 1999-05-14
PT1024829E (pt) 2009-03-18
EP1024829A1 (de) 2000-08-09
HUP0004831A3 (en) 2001-09-28
EP2042192A3 (de) 2009-05-27
ES2319341T3 (es) 2009-05-06
CZ20001529A3 (cs) 2000-10-11
JP3790099B2 (ja) 2006-06-28
AU729589C (en) 2001-08-30
BR9714899A (pt) 2000-08-22
IL135881A0 (en) 2001-05-20
CA2307655C (en) 2005-05-24
DK1024829T3 (da) 2009-02-09
PL187544B1 (pl) 2004-07-30
WO1999022762A1 (en) 1999-05-14
ATE417626T1 (de) 2009-01-15
US6660495B2 (en) 2003-12-09
EP2042192A2 (de) 2009-04-01
EP1024829B1 (de) 2008-12-17
JP2001521907A (ja) 2001-11-13
US20020086348A1 (en) 2002-07-04
US6350590B1 (en) 2002-02-26
CZ302352B6 (cs) 2011-03-30

Similar Documents

Publication Publication Date Title
HUP0003280A1 (hu) Apolipoprotein A-1 agonista peptidek, ezeket hatóanyagként tartalmazó gyógyászati készítmények és alkalmazásuk
FI941757A (fi) Dermatofagoideista (talopölypunkki) peräisin olevien pääallergeenien T-soluepitoopit
DE69739174D1 (de) Tolerogenefragmente aus natürlichen allergenen
HUP9901109A2 (hu) Immunogén peptidek vakcinálásra és allergia kezelésére
ATE408690T1 (de) Mutiertes rekombinantes allergen
GB2255093A (en) Hiv-1 core protein fragments
DK0769020T3 (da) Nye hIL-4-mutantproteiner som antagonister eller delvise agonister for det humane interleukin-4
ES2177927T3 (es) Composicion para provocar una reaccion inmunologica a un determinante antigenico no proteinico.
NO20001421D0 (no) T-cellevaksinasjon for behandling av multippel sklerose
PL335981A1 (en) Modified recombinative alegenes of gramminae pollen for use in specific immunotherapy, method of obtaining them and their application
WO2003054006A3 (en) Mutated hiv tat
IT8868117A0 (it) Solfonammidi di benzilidene canfora derivanti da amminoacidi e loro impiego in cosmesi particolarmente come filtri solari
AU5411594A (en) Molecule fragments (peptides) of the main allergens contained in the pollen of trees of the (fagales) order
AU2001292230A1 (en) Parietaria judaica ns-ltp antigen variants, uses thereof and compositions comprising them
AU2001295558A1 (en) Variants of phleum pratense allergenic proteins
ATE385809T1 (de) Saponin-zusammensetzungen und deren verwendung
AU8684298A (en) Identification of human allergens and t-lymphocyte antigens (in vitro)
AU2002212230A1 (en) Variants of the major allergen par j 2 of parietaria judaica
SE9903950D0 (sv) Non-anaphylactic forms of grass pollen allergen and their use
ES2180407A1 (es) Produccion en la levadura pichia pastoris, y sistema de aislamiento y purificacion, del alergeno recombinante de olea europea ole e 9 para uso en diagnosis y tratamiento de alergias.
WO2001040266A3 (de) INSEKTENGIFT-ALLERGENE MIT VERMINDERTER IgE-REAKTIVITÄT UND VERFAHREN ZU IHRER HERSTELLUNG
ES2125201A1 (es) Adn recombinante que codifica para epitopos del alergeno mayor de olea europaea ole e 1 util para el diagnostico y tratamiento de alergias.
IT1290764B1 (it) Pentapeptide per la preparazione di composizioni dermo- farmaceutiche e cosmetiche per il trattamento di lesioni od affezioni cutanee
IT1284880B1 (it) Epitopi per ige dell'allergene maggiore da parietaria judaica

Legal Events

Date Code Title Description
8364 No opposition during term of opposition