DE69737255D1 - Vorrichtung zur Messung der Teilchengrösse - Google Patents

Vorrichtung zur Messung der Teilchengrösse

Info

Publication number
DE69737255D1
DE69737255D1 DE69737255T DE69737255T DE69737255D1 DE 69737255 D1 DE69737255 D1 DE 69737255D1 DE 69737255 T DE69737255 T DE 69737255T DE 69737255 T DE69737255 T DE 69737255T DE 69737255 D1 DE69737255 D1 DE 69737255D1
Authority
DE
Germany
Prior art keywords
orifice
fluid
size
measuring
particle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69737255T
Other languages
English (en)
Other versions
DE69737255T2 (de
Inventor
Michael Anthony Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CELLFACTS INSTRUMENTS LTD., COVENTRY, GB
Original Assignee
Microbial Systems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbial Systems Ltd filed Critical Microbial Systems Ltd
Publication of DE69737255D1 publication Critical patent/DE69737255D1/de
Application granted granted Critical
Publication of DE69737255T2 publication Critical patent/DE69737255T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G01N15/13—Details pertaining to apertures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G01N2015/137—Cleaning
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/1031—Investigating individual particles by measuring electrical or magnetic effects
    • G01N15/12—Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
    • G01N2015/138—Detecting blocking debris

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Length Measuring Devices By Optical Means (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Sampling And Sample Adjustment (AREA)
DE69737255T 1996-11-20 1997-11-20 Vorrichtung zur Messung der Teilchengrösse Expired - Lifetime DE69737255T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9624096 1996-11-20
GBGB9624096.5A GB9624096D0 (en) 1996-11-20 1996-11-20 Apparatus and method of use thereof
US08/754,823 US6389912B1 (en) 1996-11-20 1996-11-21 Particle sizing apparatus and method of use thereof

Publications (2)

Publication Number Publication Date
DE69737255D1 true DE69737255D1 (de) 2007-03-08
DE69737255T2 DE69737255T2 (de) 2007-10-31

Family

ID=26310434

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69737255T Expired - Lifetime DE69737255T2 (de) 1996-11-20 1997-11-20 Vorrichtung zur Messung der Teilchengrösse

Country Status (7)

Country Link
US (1) US6389912B1 (de)
EP (1) EP0844475B1 (de)
AT (1) ATE352031T1 (de)
DE (1) DE69737255T2 (de)
DK (1) DK0844475T3 (de)
ES (1) ES2284178T3 (de)
GB (2) GB9624096D0 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
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GB9624096D0 (en) 1996-11-20 1997-01-08 Microbial Systems Ltd Apparatus and method of use thereof
US6418802B1 (en) * 1996-11-21 2002-07-16 Michael Anthony Wood Particle sizing apparatus and method of use thereof
GB9810493D0 (en) * 1998-05-16 1998-07-15 Microbial Systems Ltd Particle detector system
CA2381285C (en) 1999-08-06 2010-04-27 Ulrik Darling Larsen Particle characterisation apparatus
US6864979B2 (en) * 2000-12-08 2005-03-08 Horiba, Ltd Particle size distribution measuring apparatus
EP1316792B1 (de) * 2001-11-30 2009-09-16 Sysmex Corporation Teilchenanalysator
JP2005534895A (ja) 2002-06-11 2005-11-17 ケムパック エイ／エス 異なるタイプの白血球細胞の同時計数のための溶解試薬、カートリッジおよび自動電子細胞カウンタ
JP4359452B2 (ja) * 2003-06-26 2009-11-04 シスメックス株式会社 試料分析装置
EP1528387A3 (de) * 2003-10-27 2006-05-24 Leister Process Technologies Verfahren zur Unterscheidung von Partikeln in einem Durchflusszytometer
EP1891413B1 (de) 2005-02-10 2018-01-24 Koninklijke Philips N.V. Doppelprobenkassette und verfahren zur charakterisierung von partikeln in flüssigkeit
US8028566B2 (en) 2005-02-10 2011-10-04 Chempaq A/S Dual sample cartridge and method for characterizing particles in liquid
ES2820430T3 (es) 2005-05-09 2021-04-21 Labrador Diagnostics Llc Sistemas de fluidos para centros de atención y usos de los mismos
US11287421B2 (en) 2006-03-24 2022-03-29 Labrador Diagnostics Llc Systems and methods of sample processing and fluid control in a fluidic system
US8007999B2 (en) 2006-05-10 2011-08-30 Theranos, Inc. Real-time detection of influenza virus
US8012744B2 (en) 2006-10-13 2011-09-06 Theranos, Inc. Reducing optical interference in a fluidic device
US20080113391A1 (en) 2006-11-14 2008-05-15 Ian Gibbons Detection and quantification of analytes in bodily fluids
US8158430B1 (en) 2007-08-06 2012-04-17 Theranos, Inc. Systems and methods of fluidic sample processing
CA3170924A1 (en) 2007-10-02 2009-04-09 Labrador Diagnostics Llc Modular point-of-care devices and uses thereof
US8146407B2 (en) * 2008-06-20 2012-04-03 Beckman Coulter, Inc. Particle counter with electronic detection of aperture blockage
CA2778270C (en) 2009-10-19 2021-01-05 Theranos, Inc. Integrated health data capture and analysis system
CN102533536B (zh) * 2010-12-28 2017-04-05 深圳迈瑞生物医疗电子股份有限公司 计数器组件、鞘液阻抗计数装置及流式细胞分析仪
CN106323875B (zh) 2011-01-21 2019-07-09 西拉诺斯知识产权有限责任公司 样品使用最大化的系统和方法
US9459194B2 (en) 2013-03-14 2016-10-04 Cardio Metrix Apparatuses, processes, and systems for measuring particle size distribution and concentration
EP3867623B1 (de) 2018-10-18 2024-11-27 Cellfacts Analytics Limited Verfahren und vorrichtung zur überwachung von mikrobiellen verunreinigungen in einem industriellen prozess
CN111257204B (zh) * 2018-11-30 2021-11-23 深圳市帝迈生物技术有限公司 用于样本分析仪的微孔堵塞的侦测方法及样本分析仪
CN114543957B (zh) * 2020-11-26 2024-08-16 梅特勒-托利多(常州)测量技术有限公司 检测信号的实时处理方法及检测器
CN112683949B (zh) * 2020-11-30 2023-09-19 深圳市科曼医疗设备有限公司 一种宝石孔堵塞的检测方法、系统及存储介质

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US2656508A (en) 1949-08-27 1953-10-20 Wallace H Coulter Means for counting particles suspended in a fluid
US3259891A (en) * 1964-05-01 1966-07-05 Coulter Electronics Debris alarm
US3395344A (en) 1964-11-25 1968-07-30 Coulter Electronics Particle studying apparatus with selfclearing scanner element
US3444464A (en) 1965-11-26 1969-05-13 Coulter Electronics Multiple aperture fittings for particle analyzing apparatus
US3530381A (en) 1968-01-15 1970-09-22 Coulter Electronics Voting circuit control apparatus for multiple aperture particle analyzing device
US3567321A (en) 1968-07-22 1971-03-02 Coulter Electronics Bath for containing and receiving a plurality of aperture tubes
DE1806512B2 (de) 1968-11-02 1971-08-12 Vorrichtung zum klassieren von in einer untersuchungs fluessigkeit suspendierten partikeln
US3678382A (en) 1970-04-09 1972-07-18 Coulter Electronics Malfunction detection circuit and method
US3739258A (en) 1971-08-20 1973-06-12 Iit Res Inst Method and apparatus for detecting and sizing microscopic particles
CH544971A (de) 1972-03-29 1973-11-30 Contraves Ag Verfahren zum Feststellen von Fehlern beim Zählen von in einem bestimmten Flüssigkeitsvolumen enthaltenen Teilchen
GB1371432A (en) 1972-05-12 1974-10-23 Coulter Electronics Particle study apparatus having particle resolution means
US3783376A (en) * 1972-06-21 1974-01-01 Becton Dickinson Co Particle counter having removable aperture slide
US3768084A (en) 1972-07-14 1973-10-23 Becton Dickinson Co Particle counter having a clog and bubble alarm
US3973194A (en) * 1972-08-07 1976-08-03 Becton, Dickinson And Company Particle counter
DD102215A1 (de) 1973-02-02 1973-12-12
US3863056A (en) 1973-06-29 1975-01-28 Coulter Electronics Method and apparatus for multichannel voting
US3930736A (en) 1974-07-01 1976-01-06 Coulter Electronics, Inc. Aperture tube with attached thief
US3963984A (en) 1974-11-04 1976-06-15 Coulter Electronics, Inc. Method and system for cleaning an aperture in a particle study device
US4014611A (en) 1975-04-30 1977-03-29 Coulter Electronics, Inc. Aperture module for use in particle testing apparatus
US4078211A (en) 1976-09-29 1978-03-07 Coulter Electronics, Inc. Method and apparatus for balancing particle detecting signals generated in a particle study device having multiple apertures
IL53921A (en) 1977-02-15 1979-12-30 Coulter Electronics Electronic particle sensing aperture module with perforated electrode
US4290011A (en) 1978-05-18 1981-09-15 Particle Data, Inc. Particle length and volume comeasurement with controlled orientation
US4491786A (en) 1978-09-13 1985-01-01 Coulter Electronics, Inc. Transducer for measuring particles suspended in a fluid
FR2472183B1 (fr) 1979-12-12 1986-03-07 Coulter Electronics Procede de nettoyage d'une ouverture pour un dispositif d'etude de particules et appareil pour la mise en oeuvre de ce procede
US4412175A (en) 1981-04-30 1983-10-25 Coulter Electronics, Inc. Debris alarm
US4450435A (en) * 1981-11-30 1984-05-22 Bobby Dencil James Analog debris alarm
US4600880A (en) 1983-03-03 1986-07-15 Limca Research Inc. Apparatus for the detection and measurement of particulates in molten metal
US4564803A (en) 1983-08-29 1986-01-14 Coulter Corporation Method and apparatus for removing foreign matter from a flow cell of a particle study device
GB8410500D0 (en) 1984-04-25 1984-05-31 Orbec Ltd Monitoring particles in liquids
FR2569477B1 (fr) 1984-08-24 1987-01-02 Descartes Universite Rene Appareil et procede pour la determination de la deformabilite des globules rouges du sang
GB8505047D0 (en) 1985-02-27 1985-03-27 Alcan Int Ltd Studying particles
US4775833A (en) 1986-10-03 1988-10-04 Coulter Electronics, Inc. Lodged debris detector for a particle analyzer
DE3786657D1 (de) 1987-02-17 1993-08-26 Ratcom Inc Durchflusszytometrie.
US4977517A (en) 1988-09-21 1990-12-11 Toni Diagnostics, Inc. Leak and clog detection and removal system for use with particle counters
JPH06502486A (ja) 1990-07-17 1994-03-17 マーク　ジェイ．パスラ 血液テスト装置
JP2965688B2 (ja) * 1990-11-30 1999-10-18 シスメックス株式会社 粒子検出装置
JPH07301595A (ja) 1994-05-09 1995-11-14 Toa Medical Electronics Co Ltd 粒子測定装置およびその粒子測定方法
GB9624096D0 (en) 1996-11-20 1997-01-08 Microbial Systems Ltd Apparatus and method of use thereof

Also Published As

Publication number Publication date
ATE352031T1 (de) 2007-02-15
GB9724611D0 (en) 1998-01-21
GB2319618A (en) 1998-05-27
US6389912B1 (en) 2002-05-21
DE69737255T2 (de) 2007-10-31
EP0844475B1 (de) 2007-01-17
GB9624096D0 (en) 1997-01-08
EP0844475A3 (de) 1999-12-08
GB2319618B (en) 2000-08-23
ES2284178T3 (es) 2007-11-01
EP0844475A2 (de) 1998-05-27
DK0844475T3 (da) 2007-05-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: CELLFACTS INSTRUMENTS LTD., COVENTRY, GB