DE69735897D1 - Induzierende faktiren des endoderm-, herz- und neuronalen gewebes - Google Patents

Induzierende faktiren des endoderm-, herz- und neuronalen gewebes

Info

Publication number
DE69735897D1
DE69735897D1 DE69735897T DE69735897T DE69735897D1 DE 69735897 D1 DE69735897 D1 DE 69735897D1 DE 69735897 T DE69735897 T DE 69735897T DE 69735897 T DE69735897 T DE 69735897T DE 69735897 D1 DE69735897 D1 DE 69735897D1
Authority
DE
Germany
Prior art keywords
frzb
cerberus
designated
growth factors
endoderm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69735897T
Other languages
English (en)
Inventor
Robertis M De
Tewis Bouwmeester
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California filed Critical University of California
Application granted granted Critical
Publication of DE69735897D1 publication Critical patent/DE69735897D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69735897T 1996-06-20 1997-06-19 Induzierende faktiren des endoderm-, herz- und neuronalen gewebes Expired - Fee Related DE69735897D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2015096P 1996-06-20 1996-06-20
US08/878,474 US6133232A (en) 1996-06-20 1997-06-18 Endoderm, cardiac and neural inducing factors
PCT/US1997/010942 WO1997048275A1 (en) 1996-06-20 1997-06-19 Endoderm, cardiac and neural inducing factors

Publications (1)

Publication Number Publication Date
DE69735897D1 true DE69735897D1 (de) 2006-06-22

Family

ID=26693096

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69735897T Expired - Fee Related DE69735897D1 (de) 1996-06-20 1997-06-19 Induzierende faktiren des endoderm-, herz- und neuronalen gewebes

Country Status (8)

Country Link
US (1) US6133232A (de)
EP (1) EP0973391B1 (de)
JP (1) JP2002514043A (de)
AT (1) ATE326138T1 (de)
AU (1) AU723210B2 (de)
CA (1) CA2258789A1 (de)
DE (1) DE69735897D1 (de)
WO (1) WO1997048275A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998016641A1 (en) * 1996-10-11 1998-04-23 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Isolation and method of using tissue growth-inducing frzb protein
US6884871B2 (en) * 1996-10-11 2005-04-26 The United States Of America As Represented By The Department Of Health And Human Services Isolation and use of tissue growth-inducing Frzb protein
US7049291B2 (en) 1996-10-11 2006-05-23 The United States Of America As Represented By The Department Of Health And Human Services Isolation and method of using tissue growth-inducing Frzb protein
WO1998034951A1 (en) * 1997-02-11 1998-08-13 Amrad Operations Pty. Ltd. A new cytokine family and uses thereof
AU741708B2 (en) * 1997-02-11 2001-12-06 Amrad Operations Pty. Limited A new cytokine family and uses thereof
EP0975752A1 (de) * 1997-04-29 2000-02-02 Regeneron Pharmaceuticals, Inc. Menschliches cerberusprotein
US6165748A (en) * 1997-07-11 2000-12-26 Genetics Institute, Inc. Frazzled nucleotide sequences and expression products
DE19747418C1 (de) * 1997-10-27 1999-07-15 Deutsches Krebsforsch Inhibitor-Protein des wnt-Signalwegs
US20030096951A1 (en) * 1998-08-14 2003-05-22 Kenneth Jacobs Secreted proteins and polynucleotides encoding them
US6344541B1 (en) 1998-09-25 2002-02-05 Amgen Inc. DKR polypeptides
DE10119727A1 (de) 2001-04-21 2002-10-31 Bayer Cropscience Gmbh Synergistische herbizide Mittel enthaltend Herbizide aus der Gruppe der Benzoylcyclohexandione für den Einsatz in Reis-Kulturen
DE10119728A1 (de) 2001-04-21 2002-10-31 Bayer Cropscience Gmbh Synergistische herbizide Mittel enthaltend Herbizide aus der Gruppe der Benzoylcyclohexandione für den Einsatz in Reis-Kulturen
DE10119729A1 (de) 2001-04-21 2002-10-31 Bayer Cropscience Gmbh Synergistische herbizide Mittel enthaltend Herbizide aus der Gruppe Benzoylcyclohexandione für den Einsatz in Mais-Kulturen
US7713526B2 (en) * 2001-05-01 2010-05-11 The Regents Of The University Of California Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas
US20030044409A1 (en) * 2001-05-01 2003-03-06 Carson Dennis A. Immunologic compositions and methods for studying and treating cancers expressing frizzled antigens
US7682607B2 (en) * 2001-05-01 2010-03-23 The Regents Of The University Of California Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas
US7193069B2 (en) * 2002-03-22 2007-03-20 Research Association For Biotechnology Full-length cDNA
WO2005115439A2 (en) * 2004-05-27 2005-12-08 Acceleron Pharma Inc. Cerberus/coco derivatives and uses thereof
US9045553B2 (en) 2004-05-27 2015-06-02 Acceleron Pharma, Inc. Cerberus/Coco derivatives and uses thereof
AU2007332819A1 (en) * 2006-12-08 2008-06-19 Acceleron Pharma Inc. Uses of cerberus, coco and derivatives thereof
ES2903029T3 (es) 2014-07-03 2022-03-30 Univ Yale La inhibición de DICKKOPF2 (DKK2) suprime la formación de tumores
KR20180085723A (ko) 2015-10-28 2018-07-27 예일 유니버시티 인간화 항-dkk2 항체 및 이의 용도

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE194658T1 (de) * 1992-09-03 2000-07-15 Univ California Das dorsalgewebe beeinflussender faktor
JP3431153B2 (ja) * 1992-09-03 2003-07-28 リジエネロン・フアーマシユーテイカルズ・インコーポレーテツド 背側組織作用因子及び組成物
US5457048A (en) * 1993-12-03 1995-10-10 La Jolla Cancer Research Foundation Eph-related tyrosine kinases, nucleotide sequences and methods of use

Also Published As

Publication number Publication date
EP0973391A1 (de) 2000-01-26
AU3576597A (en) 1998-01-07
JP2002514043A (ja) 2002-05-14
US6133232A (en) 2000-10-17
EP0973391A4 (de) 2003-09-03
EP0973391B1 (de) 2006-05-17
ATE326138T1 (de) 2006-06-15
WO1997048275A1 (en) 1997-12-24
AU723210B2 (en) 2000-08-17
CA2258789A1 (en) 1997-12-24

Similar Documents

Publication Publication Date Title
DE69735897D1 (de) Induzierende faktiren des endoderm-, herz- und neuronalen gewebes
Bosch et al. Axonal signals regulate expression of glia maturation factor-beta in Schwann cells: an immunohistochemical study of injured sciatic nerves and cultured Schwann cells
CA2596597A1 (en) Method for stimulation collagen synthesis and/or kgf expression
DE602004026898D1 (de) Zusammensetzungen für die diagnose und therapie von erkrankungen, die im zusammenhang mit einer anomalen expression von futrinen (r-spondinen) stehen
BR9916461A (pt) ácidos carboxìlicos e isósteres de ácido carboxìlico de compostos n-heterocìclicos
DE69840909D1 (de) Analoge von kokain
DE69527049D1 (de) Therapeutische verwendungen von bakterizide/permeabilitätserhöhende protein dimer produkte
WO1996019580A3 (en) Telomerase protein component
EA200001247A1 (ru) N-связанные сульфонамиды n-гетероциклических карбоновых кислот или изостеры карбоновых кислот
WO2001066596A3 (en) Human fgf-23 gene and gene expression products
ATE337339T1 (de) Therapeutische verwendung von smr1 protein und seinen aktiven derivaten
DE69221486D1 (de) Bombesinanaloge
CA2193993A1 (en) New hil-4 mutant proteins used as antagonists or partial agonists of human interleukin 4
DE60138552D1 (de) Peptide mit integrinbindungsmotiv und behandlungsmethoden für muskelkrankheiten
MX9307983A (es) Derivados de aminoacidos de heterociclos como inhibidores de la proteina quinasa c.
ATE294236T1 (de) Promotor der tie rezeptor protein kinase
ES2096556T3 (es) Secuencias de adn, moleculas de adn recombinante y procedimientos para producir lipocortinas iii, iv, v y vi.
NZ332829A (en) Use of a polypeptide corresponding to a serine threonine kinase receptor, ALK-7 for neurological diseases
DE69501359D1 (de) Verwendung von Phosphatdiestern zur Behandlung von Erkrankungen der Retina
DK0948536T3 (da) G-protein-koblet receptor med et forstörret extracellulært domæne
ES2135398T3 (es) Compuesto y composiciones de inhibicion de la resorcion osea.
KR100488038B1 (ko) 기관 보호 활성을 지닌 신규한 신체 보호 화합물 펩티드염, 이의 제조 방법 및 치료에서의 이의 용도
EP1059931B1 (de) Verwendung von cd137 zur förderung der proliferation peripherer monocyten
DE69102069D1 (de) 5-aminosalicylsäurederivate zur therapie chronisch entzündlicher baucherkrankungen.
KR960000248A (ko) 골대사 질환 치료제

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee