DE69733933D1 - Neue Liganden des Neuropeptide Rezeptors HFGAN72 - Google Patents
Neue Liganden des Neuropeptide Rezeptors HFGAN72Info
- Publication number
- DE69733933D1 DE69733933D1 DE69733933T DE69733933T DE69733933D1 DE 69733933 D1 DE69733933 D1 DE 69733933D1 DE 69733933 T DE69733933 T DE 69733933T DE 69733933 T DE69733933 T DE 69733933T DE 69733933 D1 DE69733933 D1 DE 69733933D1
- Authority
- DE
- Germany
- Prior art keywords
- hfgan72
- neuropeptide receptor
- new ligands
- ligands
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3360496P | 1996-12-17 | 1996-12-17 | |
US33604P | 1996-12-17 | ||
US82051997A | 1997-03-19 | 1997-03-19 | |
US820519 | 1997-03-19 | ||
US88738297A | 1997-07-02 | 1997-07-02 | |
US887382 | 1997-07-02 | ||
US08/939,093 US6309854B1 (en) | 1996-12-17 | 1997-09-26 | Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72 |
US939093 | 1997-09-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69733933D1 true DE69733933D1 (de) | 2005-09-15 |
DE69733933T2 DE69733933T2 (de) | 2006-01-26 |
Family
ID=27488130
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69733933T Expired - Lifetime DE69733933T2 (de) | 1996-12-17 | 1997-12-17 | Neue Liganden des Neuropeptid Rezeptors HFGAN72 |
DE0849361T Pending DE849361T1 (de) | 1996-12-17 | 1997-12-17 | Neue Liganden des Neuropeptide Rezeptors HFGAN72 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE0849361T Pending DE849361T1 (de) | 1996-12-17 | 1997-12-17 | Neue Liganden des Neuropeptide Rezeptors HFGAN72 |
Country Status (5)
Country | Link |
---|---|
US (2) | US6309854B1 (de) |
EP (1) | EP0849361B1 (de) |
JP (1) | JP3946847B2 (de) |
CA (1) | CA2218452C (de) |
DE (2) | DE69733933T2 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000516456A (ja) * | 1996-08-02 | 2000-12-12 | ザ・スクリプス・リサーチ・インステイチユート | 視床下部特異的ポリペプチド |
US6020157A (en) * | 1997-04-30 | 2000-02-01 | Smithkline Beecham Corporation | Polynucleotides encoding HFGAN72X receptor |
US5935814A (en) * | 1997-04-30 | 1999-08-10 | Smithkline Beecham Corporation | Polynucleotides encoding HFGAN72Y receptor |
JP2003527302A (ja) * | 1997-12-15 | 2003-09-16 | スミスクライン ビーチャム パブリック リミテッド カンパニー | 新規な神経ペプチドレセプターhfgan72のリガンドおよびそのアゴニストまたはアンタゴニストを用いる治療方法 |
EP1352651A3 (de) * | 1999-02-12 | 2003-11-12 | Smithkline Beecham Plc | Neue Verwendung von Orexinrezeptorantagonisten |
WO2000047576A1 (en) * | 1999-02-12 | 2000-08-17 | Smithkline Beecham Plc | Cinnamide derivatives as orexin-1 receptors antagonists |
WO2001000787A2 (en) * | 1999-06-25 | 2001-01-04 | Smithkline Beecham Corporation | Methods of treatment using lig 72a and variants thereof |
WO2001083558A1 (en) * | 2000-05-03 | 2001-11-08 | Astrazeneca Ab | Agonists/antagonists of the gpr56 receptor as appetite control agents |
US20020166135A1 (en) * | 2000-12-20 | 2002-11-07 | Waleh Nahid S. | Modulators of the hypocretin system and methods of screening therefor |
US7241579B2 (en) | 2000-12-22 | 2007-07-10 | Smithkline Beecham Corporation | Method of screening for GPR40 ligands |
GB0031527D0 (en) * | 2000-12-22 | 2001-02-07 | Smithkline Beecham Plc | New use |
IL158463A0 (en) | 2001-05-05 | 2004-05-12 | Smithkline Beecham Plc | N-aroyl cyclic amines |
WO2004071395A2 (en) * | 2003-02-17 | 2004-08-26 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled receptor ox1r (ox1r) |
US8129384B2 (en) | 2008-10-09 | 2012-03-06 | Glaxo Group Limited | Imidazo[1,2-a]pyrazines as orexin receptor antagonists |
US8093255B2 (en) | 2008-10-09 | 2012-01-10 | Glaxo Group Limited | Imidazo[1,2-A]pyrimidines as orexin receptor antagonists |
GB0823467D0 (en) | 2008-12-23 | 2009-01-28 | Glaxo Group Ltd | Novel Compounds |
CN102459229A (zh) | 2009-04-24 | 2012-05-16 | 葛兰素集团有限公司 | 用作食欲肽拮抗剂的3-氮杂二环[4.1.0]庚烷 |
EP2470525A1 (de) | 2009-08-24 | 2012-07-04 | Glaxo Group Limited | Piperidinderivate als orexinantagonisten |
EP2470523A1 (de) | 2009-08-24 | 2012-07-04 | Glaxo Group Limited | 5-methyl-piperidinderivate als orexinrezeptor-antagonisten zur behandlung von schlafstörungen |
BR112013006594B1 (pt) | 2010-09-22 | 2021-08-17 | Eisai R&D Management Co., Ltd | Composto ciclopropano antagonista de receptor da orexina e composição farmacêutica |
WO2012089606A1 (en) | 2010-12-28 | 2012-07-05 | Glaxo Group Limited | Azabicyclo [4.1.0] hept - 4 - yl derivatives as human orexin receptor antagonists |
WO2012089607A1 (en) | 2010-12-28 | 2012-07-05 | Glaxo Group Limited | Novel compounds with a 3a-azabicyclo [4.1.0] heptane core acting on orexin receptors |
US20150140015A1 (en) * | 2013-11-15 | 2015-05-21 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and pharmaceutical compositions for the treatment of pancreatic cancer |
RU2703297C2 (ru) | 2014-10-23 | 2019-10-16 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Композиции и способы для лечения бессонницы |
RU2647771C2 (ru) * | 2016-04-26 | 2018-03-19 | Общество с ограниченной ответственностью "Орексал" (ООО "Орексал") | Способ получения рекомбинантного орексина а человека, плазмидная днк, штамм-продуцент |
WO2017194548A1 (en) | 2016-05-10 | 2017-11-16 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of autoimmune inflammatory diseases |
TW202137986A (zh) | 2019-12-20 | 2021-10-16 | 日商衛材R&D企管股份有限公司 | 治療失眠之方法 |
IL299125A (en) | 2020-07-17 | 2023-02-01 | Eisai R&D Man Co Ltd | A converted compound of piperidine and its use |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4855393A (en) * | 1992-09-10 | 1994-03-29 | New York University | Polypeptides of g-coupled receptor proteins, and compositions and methods thereof |
CA2220036A1 (en) * | 1995-05-05 | 1996-11-07 | Human Genome Sciences, Inc. | Human neuropeptide receptor |
JP2000516456A (ja) | 1996-08-02 | 2000-12-12 | ザ・スクリプス・リサーチ・インステイチユート | 視床下部特異的ポリペプチド |
US6001963A (en) * | 1996-12-17 | 1999-12-14 | Smithkline Beecham Corporation | Ligands of the neuropeptide receptor HFGAN72 |
-
1997
- 1997-09-26 US US08/939,093 patent/US6309854B1/en not_active Expired - Lifetime
- 1997-12-16 CA CA002218452A patent/CA2218452C/en not_active Expired - Lifetime
- 1997-12-17 DE DE69733933T patent/DE69733933T2/de not_active Expired - Lifetime
- 1997-12-17 EP EP97310216A patent/EP0849361B1/de not_active Expired - Lifetime
- 1997-12-17 DE DE0849361T patent/DE849361T1/de active Pending
- 1997-12-17 JP JP37002297A patent/JP3946847B2/ja not_active Expired - Lifetime
-
2000
- 2000-12-15 US US09/737,379 patent/US6750026B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP3946847B2 (ja) | 2007-07-18 |
EP0849361B1 (de) | 2005-08-10 |
US6309854B1 (en) | 2001-10-30 |
US6750026B2 (en) | 2004-06-15 |
CA2218452C (en) | 2001-12-04 |
JPH10229887A (ja) | 1998-09-02 |
DE849361T1 (de) | 2001-01-25 |
DE69733933T2 (de) | 2006-01-26 |
US20020082202A1 (en) | 2002-06-27 |
EP0849361A3 (de) | 2000-04-19 |
EP0849361A2 (de) | 1998-06-24 |
CA2218452A1 (en) | 1998-06-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |