EP0828751A4 - Humaner neuropeptidrezeptor - Google Patents

Humaner neuropeptidrezeptor

Info

Publication number
EP0828751A4
EP0828751A4 EP95918991A EP95918991A EP0828751A4 EP 0828751 A4 EP0828751 A4 EP 0828751A4 EP 95918991 A EP95918991 A EP 95918991A EP 95918991 A EP95918991 A EP 95918991A EP 0828751 A4 EP0828751 A4 EP 0828751A4
Authority
EP
European Patent Office
Prior art keywords
neuropeptide receptor
human neuropeptide
human
receptor
neuropeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95918991A
Other languages
English (en)
French (fr)
Other versions
EP0828751A1 (de
Inventor
Daniel R Soppet
Yi Li
Craig A Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP0828751A1 publication Critical patent/EP0828751A1/de
Publication of EP0828751A4 publication Critical patent/EP0828751A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP95918991A 1995-05-05 1995-05-05 Humaner neuropeptidrezeptor Withdrawn EP0828751A4 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/US1995/005616 WO1996034877A1 (en) 1995-05-05 1995-05-05 Human neuropeptide receptor
CA002220036A CA2220036A1 (en) 1995-05-05 1995-05-05 Human neuropeptide receptor

Publications (2)

Publication Number Publication Date
EP0828751A1 EP0828751A1 (de) 1998-03-18
EP0828751A4 true EP0828751A4 (de) 1999-01-20

Family

ID=25679790

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95918991A Withdrawn EP0828751A4 (de) 1995-05-05 1995-05-05 Humaner neuropeptidrezeptor

Country Status (3)

Country Link
EP (1) EP0828751A4 (de)
CA (1) CA2220036A1 (de)
WO (1) WO1996034877A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410701B1 (en) 1995-05-05 2002-06-25 Human Genome Sciences, Inc. Human neuropeptide receptor
US20030022277A1 (en) * 1995-05-05 2003-01-30 Daniel R. Soppet Human neuropeptide receptor
US6309854B1 (en) * 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US6001963A (en) * 1996-12-17 1999-12-14 Smithkline Beecham Corporation Ligands of the neuropeptide receptor HFGAN72
AU735760B2 (en) * 1997-04-24 2001-07-12 Merck Sharp & Dohme Limited Use of a NK-1 receptor antagonist and an SSRI for treating obesity
US5935814A (en) * 1997-04-30 1999-08-10 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72Y receptor
US6020157A (en) * 1997-04-30 2000-02-01 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72X receptor
CA2233584A1 (en) * 1997-06-11 1998-12-11 Smithkline Beecham Corporation 7tm receptor hlwar77
US6166193A (en) * 1997-07-25 2000-12-26 Board Of Regents, University Of Texas System Polynucleotides encoding MY1 receptor
WO1999030670A2 (en) * 1997-12-15 1999-06-24 Smithkline Beecham Plc Methods of treatment using novel ligands of the neuropeptide receptor hfgan72 and agonists or antagonists thereof
AUPP438598A0 (en) * 1998-06-29 1998-07-23 Garvan Institute Of Medical Research NPY-Y7 receptor gene
JP2002536425A (ja) * 1999-02-12 2002-10-29 スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー オレキシン受容体アンタゴニストの新規用途
US6319710B1 (en) 1999-08-23 2001-11-20 Decode Genetics Ehf. Human narcolepsy gene
US6410712B1 (en) * 1999-10-25 2002-06-25 Decode Genetics Ehf. Human narcolepsy gene
ES2263647T3 (es) * 2000-08-25 2006-12-16 Phase One Pharma Oy Ltd. Metodo para reducir la sobreproduccion inducida por estres de neuropeptido y en un individuo.
BR0209334A (pt) 2001-05-05 2004-06-15 Smithkline Beecham Plc Aminas n-aroil cìclicas
US8093255B2 (en) 2008-10-09 2012-01-10 Glaxo Group Limited Imidazo[1,2-A]pyrimidines as orexin receptor antagonists
US8129384B2 (en) 2008-10-09 2012-03-06 Glaxo Group Limited Imidazo[1,2-a]pyrazines as orexin receptor antagonists
GB0823467D0 (en) 2008-12-23 2009-01-28 Glaxo Group Ltd Novel Compounds
EA201171293A1 (ru) 2009-04-24 2012-05-30 Глэксо Груп Лимитед 3-азабицикло[4.1.0]гептаны, применяемые в качестве антагонистов орексина
EP2470523A1 (de) 2009-08-24 2012-07-04 Glaxo Group Limited 5-methyl-piperidinderivate als orexinrezeptor-antagonisten zur behandlung von schlafstörungen
EP2470525A1 (de) 2009-08-24 2012-07-04 Glaxo Group Limited Piperidinderivate als orexinantagonisten
BR112013006594B1 (pt) 2010-09-22 2021-08-17 Eisai R&D Management Co., Ltd Composto ciclopropano antagonista de receptor da orexina e composição farmacêutica
WO2012089606A1 (en) 2010-12-28 2012-07-05 Glaxo Group Limited Azabicyclo [4.1.0] hept - 4 - yl derivatives as human orexin receptor antagonists
WO2012089607A1 (en) 2010-12-28 2012-07-05 Glaxo Group Limited Novel compounds with a 3a-azabicyclo [4.1.0] heptane core acting on orexin receptors
KR102325655B1 (ko) 2014-08-06 2021-11-15 에자이 알앤드디 매니지먼트 가부시키가이샤 피리미딘-1-올 화합물의 제조 방법, 및 이의 중간체
MX2017004950A (es) 2014-10-23 2018-01-16 Eisai R&D Man Co Ltd Composiciones y metodos para tratar el insomnio.
BR112022002949A2 (pt) 2019-09-13 2022-06-07 Eisai R&D Man Co Ltd Composição farmacêutica para tratar insônia
BR112022012246A2 (pt) 2019-12-20 2022-08-30 Eisai R&D Man Co Ltd Uso de lemborexant para tratar insônia
TW202216705A (zh) 2020-07-17 2022-05-01 日商衛材R&D企管股份有限公司 取代哌啶化合物及其用途
TW202334120A (zh) 2022-01-14 2023-09-01 日商衛材R&D企管股份有限公司 經取代之哌啶化合物之結晶以及經取代之哌啶化合物之鹽及其等之結晶

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005302A1 (en) * 1994-08-11 1996-02-22 Takeda Chemical Industries, Ltd. G protein coupled receptor protein, production, and use thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005302A1 (en) * 1994-08-11 1996-02-22 Takeda Chemical Industries, Ltd. G protein coupled receptor protein, production, and use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
H.HERZOG ET AL.: "Genomic Organization, Localization, and Allelic Differences in the Gene for the Human Neuropeptide Y Y1 Receptor", J.BIOL.CHEM., vol. 268, no. 9, 1993, pages 6703 - 7, XP002083378 *
See also references of WO9634877A1 *

Also Published As

Publication number Publication date
EP0828751A1 (de) 1998-03-18
WO1996034877A1 (en) 1996-11-07
CA2220036A1 (en) 1996-11-07

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Legal Events

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