EP0828751A4 - Recepteur de neuropeptides humain - Google Patents

Recepteur de neuropeptides humain

Info

Publication number
EP0828751A4
EP0828751A4 EP95918991A EP95918991A EP0828751A4 EP 0828751 A4 EP0828751 A4 EP 0828751A4 EP 95918991 A EP95918991 A EP 95918991A EP 95918991 A EP95918991 A EP 95918991A EP 0828751 A4 EP0828751 A4 EP 0828751A4
Authority
EP
European Patent Office
Prior art keywords
neuropeptide receptor
human neuropeptide
human
receptor
neuropeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP95918991A
Other languages
German (de)
English (en)
Other versions
EP0828751A1 (fr
Inventor
Daniel R Soppet
Yi Li
Craig A Rosen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of EP0828751A1 publication Critical patent/EP0828751A1/fr
Publication of EP0828751A4 publication Critical patent/EP0828751A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
EP95918991A 1995-05-05 1995-05-05 Recepteur de neuropeptides humain Withdrawn EP0828751A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002220036A CA2220036A1 (fr) 1995-05-05 1995-05-05 Recepteur de neuropeptides humain
PCT/US1995/005616 WO1996034877A1 (fr) 1995-05-05 1995-05-05 Recepteur de neuropeptides humain

Publications (2)

Publication Number Publication Date
EP0828751A1 EP0828751A1 (fr) 1998-03-18
EP0828751A4 true EP0828751A4 (fr) 1999-01-20

Family

ID=25679790

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95918991A Withdrawn EP0828751A4 (fr) 1995-05-05 1995-05-05 Recepteur de neuropeptides humain

Country Status (3)

Country Link
EP (1) EP0828751A4 (fr)
CA (1) CA2220036A1 (fr)
WO (1) WO1996034877A1 (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410701B1 (en) 1995-05-05 2002-06-25 Human Genome Sciences, Inc. Human neuropeptide receptor
US20030022277A1 (en) * 1995-05-05 2003-01-30 Daniel R. Soppet Human neuropeptide receptor
US6309854B1 (en) * 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US6001963A (en) * 1996-12-17 1999-12-14 Smithkline Beecham Corporation Ligands of the neuropeptide receptor HFGAN72
CA2287397A1 (fr) * 1997-04-24 1998-10-29 Merck Sharp & Dohme Limited Utilisation d'un antagoniste du recepteur nk-1 et d'un inhibiteur selectif de reabsorption de la serotonine (ssri) dans le traitement de l'obesite
US5935814A (en) * 1997-04-30 1999-08-10 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72Y receptor
US6020157A (en) * 1997-04-30 2000-02-01 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72X receptor
CA2233584A1 (fr) * 1997-06-11 1998-12-11 Smithkline Beecham Corporation Hlwar77 codant pour un recepteur 7tm
US6166193A (en) * 1997-07-25 2000-12-26 Board Of Regents, University Of Texas System Polynucleotides encoding MY1 receptor
WO1999030670A2 (fr) * 1997-12-15 1999-06-24 Smithkline Beecham Plc Procedes de traitement utilisant de nouveaux ligands du recepteur hfgan72 de neuropeptides et leurs agonistes ou antagonistes
AUPP438598A0 (en) * 1998-06-29 1998-07-23 Garvan Institute Of Medical Research NPY-Y7 receptor gene
WO2000047284A2 (fr) * 1999-02-12 2000-08-17 Smithkline Beecham P.L.C. Nouvelle utilisation des antagonistes des recepteurs de l'orexine
US6319710B1 (en) 1999-08-23 2001-11-20 Decode Genetics Ehf. Human narcolepsy gene
US6410712B1 (en) * 1999-10-25 2002-06-25 Decode Genetics Ehf. Human narcolepsy gene
ES2263647T3 (es) * 2000-08-25 2006-12-16 Phase One Pharma Oy Ltd. Metodo para reducir la sobreproduccion inducida por estres de neuropeptido y en un individuo.
AU2002253361B2 (en) 2001-05-05 2006-08-17 Smithkline Beecham P.L.C. N-aroyl cyclic amines
US8093255B2 (en) 2008-10-09 2012-01-10 Glaxo Group Limited Imidazo[1,2-A]pyrimidines as orexin receptor antagonists
US8129384B2 (en) 2008-10-09 2012-03-06 Glaxo Group Limited Imidazo[1,2-a]pyrazines as orexin receptor antagonists
GB0823467D0 (en) 2008-12-23 2009-01-28 Glaxo Group Ltd Novel Compounds
JP2012524760A (ja) 2009-04-24 2012-10-18 グラクソ グループ リミテッド オレキシンアンタゴニストとして使用される３−アザビシクロ［４．１．０］ヘプタン
WO2011023585A1 (fr) 2009-08-24 2011-03-03 Glaxo Group Limited Dérivés de pipéridine utilisés comme antagonistes d'orexines
JP2013502447A (ja) 2009-08-24 2013-01-24 グラクソ グループ リミテッド 睡眠障害の治療のためのオレキシン受容体アンタゴニストとしての５−メチル−ピペリジン誘導体
EP2626350B1 (fr) 2010-09-22 2015-04-15 Eisai R&D Management Co., Ltd. Composé de cyclopropane
WO2012089607A1 (fr) 2010-12-28 2012-07-05 Glaxo Group Limited Nouveaux composés dotés d'un cœur 3a-azabicyclo[4.1.0]heptane agissant sur les récepteurs d'orexine
WO2012089606A1 (fr) 2010-12-28 2012-07-05 Glaxo Group Limited Dérivés azabicyclo [4.1.0] hept-4-yle en tant qu'antagonistes du récepteur humain de l'orexine
WO2016021539A1 (fr) 2014-08-06 2016-02-11 エーザイ・アール・アンド・ディー・マネジメント株式会社 Procédé de fabrication de composé pyrimidine-1-ol, et intermédiaire de celui-ci
SG11201703064WA (en) 2014-10-23 2017-05-30 Eisai R&D Man Co Ltd Compositions and methods for treating insomnia
EP3993801A4 (fr) 2019-09-13 2023-07-19 Eisai R&D Management Co., Ltd. Composition pharmaceutique pour le traitement de l'insomnie
KR20220119065A (ko) 2019-12-20 2022-08-26 에자이 알앤드디 매니지먼트 가부시키가이샤 불면증 치료를 위한 렘보렉산트의 용도
AU2021308053A1 (en) 2020-07-17 2023-02-02 Eisai R&D Management Co., Ltd. Substituted piperidine compound and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005302A1 (fr) * 1994-08-11 1996-02-22 Takeda Chemical Industries, Ltd. Proteine receptrice couplee a une proteine g, sa production et son utilisation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996005302A1 (fr) * 1994-08-11 1996-02-22 Takeda Chemical Industries, Ltd. Proteine receptrice couplee a une proteine g, sa production et son utilisation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
H.HERZOG ET AL.: "Genomic Organization, Localization, and Allelic Differences in the Gene for the Human Neuropeptide Y Y1 Receptor", J.BIOL.CHEM., vol. 268, no. 9, 1993, pages 6703 - 7, XP002083378 *
See also references of WO9634877A1 *

Also Published As

Publication number Publication date
WO1996034877A1 (fr) 1996-11-07
CA2220036A1 (fr) 1996-11-07
EP0828751A1 (fr) 1998-03-18

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Legal Events

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