DE69726889T2 - Hypothalamus-spezifische polypeptide - Google Patents

Hypothalamus-spezifische polypeptide Download PDF

Info

Publication number
DE69726889T2
DE69726889T2 DE69726889T DE69726889T DE69726889T2 DE 69726889 T2 DE69726889 T2 DE 69726889T2 DE 69726889 T DE69726889 T DE 69726889T DE 69726889 T DE69726889 T DE 69726889T DE 69726889 T2 DE69726889 T2 DE 69726889T2
Authority
DE
Germany
Prior art keywords
hypocretin
hypothalamus
methods
specific polypeptides
polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69726889T
Other languages
English (en)
Other versions
DE69726889D1 (de
Inventor
Gregor Sutcliffe
M Gautvik
Lecea Luis De
E Bloom
E Danielson
T Gautvik
S Kilduff
E Foye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21813781&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69726889(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of DE69726889D1 publication Critical patent/DE69726889D1/de
Application granted granted Critical
Publication of DE69726889T2 publication Critical patent/DE69726889T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69726889T 1996-08-02 1997-08-01 Hypothalamus-spezifische polypeptide Expired - Fee Related DE69726889T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2322096P 1996-08-02 1996-08-02
PCT/US1997/013657 WO1998005352A1 (en) 1996-08-02 1997-08-01 Hypothalamus-specific polypeptides

Publications (2)

Publication Number Publication Date
DE69726889D1 DE69726889D1 (de) 2004-01-29
DE69726889T2 true DE69726889T2 (de) 2004-10-21

Family

ID=21813781

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69726889T Expired - Fee Related DE69726889T2 (de) 1996-08-02 1997-08-01 Hypothalamus-spezifische polypeptide

Country Status (8)

Country Link
US (2) US6635479B1 (de)
EP (1) EP1007074B1 (de)
JP (1) JP2000516456A (de)
AT (1) ATE256739T1 (de)
AU (1) AU721644B2 (de)
CA (1) CA2261565A1 (de)
DE (1) DE69726889T2 (de)
WO (1) WO1998005352A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6309854B1 (en) 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US6001963A (en) * 1996-12-17 1999-12-14 Smithkline Beecham Corporation Ligands of the neuropeptide receptor HFGAN72
US7973156B2 (en) 1997-08-21 2011-07-05 Quark Pharmaceuticals Inc. Hypoxia-regulated genes
WO1999030670A2 (en) * 1997-12-15 1999-06-24 Smithkline Beecham Plc Methods of treatment using novel ligands of the neuropeptide receptor hfgan72 and agonists or antagonists thereof
US6514719B1 (en) * 1999-05-28 2003-02-04 Immunex Corporation Methods for identifying compounds that alter kinase activity
WO2001008720A2 (en) * 1999-07-30 2001-02-08 The Board Of Trustees Of The Leland Stanford Junior University Hypocretin and hypocretin receptors in regulation of sleep and related disorders
WO2002087606A2 (en) * 2000-12-20 2002-11-07 Sri International Modulators of the hypocretin system and methods of screening therefor
US7041495B2 (en) * 2000-12-21 2006-05-09 The Trustees Of The University Of Pennsylvania Pregnancy up-regulated, nonubiquitous CaM kinase
US20040142325A1 (en) * 2001-09-14 2004-07-22 Liat Mintz Methods and systems for annotating biomolecular sequences
AU2003218321A1 (en) * 2002-03-19 2003-10-08 Incyte Corporation Kinases and phosphatases
AU2003262963A1 (en) * 2002-08-29 2004-03-19 The Regents Of The University Of California Hypocretin administration as a treatment for obesity
WO2005071059A2 (en) * 2004-01-27 2005-08-04 Compugen Ltd. Methods of identifying putative gene products by interspecies sequence comparison and biomolecular sequences uncovered thereby
US20060147946A1 (en) * 2004-01-27 2006-07-06 Pinchas Akiva Novel calcium channel variants and methods of use thereof
WO2005118548A1 (en) 2004-03-01 2005-12-15 Actelion Pharmaceuticals Ltd Substituted 1,2,3,4-tetrahydroisoquinoline derivatives
JP4675623B2 (ja) * 2004-12-28 2011-04-27 本田技研工業株式会社 燃料電池システム及びその制御方法
FR2906614B1 (fr) * 2006-10-03 2019-06-07 Serguei Fetissov Methode de diagnostic de maladies neuropsychiatriques, de troubles du comportement alimentaire ou de maladies metaboliques.
AU2008306269A1 (en) * 2007-09-11 2009-04-09 Mondobiotech Laboratories Ag Astressin and beta- endorphin for use as therapeutic agents
WO2009095925A2 (en) * 2008-01-31 2009-08-06 Compugen Ltd. Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
WO2014165866A2 (en) * 2013-04-01 2014-10-09 The Board Of Trustees Of The Leland Stanford Junior University Methods for immune-based diagnosis, prevention and personalized treatment of narcolepsy
WO2023199893A1 (ja) * 2022-04-11 2023-10-19 エーザイ・アール・アンド・ディー・マネジメント株式会社 活性型オレキシンａを定量する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128242A (en) * 1989-06-19 1992-07-07 The Administrators Of The Tulane Educational Fund Hypothalamic polypeptides with adenylate cyclase stimulating activity
US6001963A (en) * 1996-12-17 1999-12-14 Smithkline Beecham Corporation Ligands of the neuropeptide receptor HFGAN72
US6309854B1 (en) * 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US5969123A (en) * 1998-03-06 1999-10-19 Millennium Biotherapeutics, Inc. Nucleic acid molecules derived from a brain tissue library

Also Published As

Publication number Publication date
DE69726889D1 (de) 2004-01-29
CA2261565A1 (en) 1998-02-12
AU721644B2 (en) 2000-07-13
EP1007074B1 (de) 2003-12-17
JP2000516456A (ja) 2000-12-12
US6635479B1 (en) 2003-10-21
AU4146497A (en) 1998-02-25
US20030176666A1 (en) 2003-09-18
EP1007074A4 (de) 2000-10-25
EP1007074A1 (de) 2000-06-14
ATE256739T1 (de) 2004-01-15
WO1998005352A1 (en) 1998-02-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee