DE69731646T2 - Verabreichung von nukleinsäurepartikeln - Google Patents
Verabreichung von nukleinsäurepartikeln Download PDFInfo
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- DE69731646T2 DE69731646T2 DE69731646T DE69731646T DE69731646T2 DE 69731646 T2 DE69731646 T2 DE 69731646T2 DE 69731646 T DE69731646 T DE 69731646T DE 69731646 T DE69731646 T DE 69731646T DE 69731646 T2 DE69731646 T2 DE 69731646T2
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- nucleic acid
- particles
- dna
- transfer
- use according
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Classifications
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/89—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microinjection
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
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- Zoology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
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| GBGB9619002.0A GB9619002D0 (en) | 1996-09-11 | 1996-09-11 | Particle delivery |
| GB9619002 | 1996-09-11 | ||
| PCT/GB1997/002478 WO1998010750A2 (en) | 1996-09-11 | 1997-09-11 | Nucleic acid particle delivery |
Publications (2)
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| DE69731646D1 DE69731646D1 (de) | 2004-12-23 |
| DE69731646T2 true DE69731646T2 (de) | 2005-12-01 |
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| DE69731646T Expired - Fee Related DE69731646T2 (de) | 1996-09-11 | 1997-09-11 | Verabreichung von nukleinsäurepartikeln |
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| Country | Link |
|---|---|
| EP (1) | EP0928190B1 (enExample) |
| JP (1) | JP2001500858A (enExample) |
| AU (1) | AU4307997A (enExample) |
| DE (1) | DE69731646T2 (enExample) |
| ES (1) | ES2234016T3 (enExample) |
| GB (1) | GB9619002D0 (enExample) |
| WO (1) | WO1998010750A2 (enExample) |
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| US7223739B1 (en) | 1995-06-07 | 2007-05-29 | Powderject Vaccines, Inc. | Adjuvanted genetic vaccines |
| US20060002949A1 (en) | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
| US5980898A (en) | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
| US6797276B1 (en) | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
| US6884435B1 (en) | 1997-01-30 | 2005-04-26 | Chiron Corporation | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
| ATE235890T1 (de) | 1997-01-30 | 2003-04-15 | Chiron Corp | Verwendung von mikropartikeln mit adsorbiertem antigen zur stimulierung der immunabwehr |
| NZ510928A (en) | 1998-10-01 | 2002-10-25 | Powderject Res Ltd | Spray coated powder composition formed from seed particles between 10-100 micrometres coated with an aqueous pharmaceutical composition |
| US6881723B1 (en) | 1998-11-05 | 2005-04-19 | Powderject Vaccines, Inc. | Nucleic acid constructs |
| PT1146861E (pt) | 1999-02-03 | 2005-10-31 | Powderject Res Ltd | Formulacoes de particulas de hidrogel |
| AU3593200A (en) | 1999-02-09 | 2000-08-29 | Powderject Vaccines, Inc. | (mycobacterium tuberculosis), immunization |
| US6565528B1 (en) | 1999-05-07 | 2003-05-20 | Scimed Life Systems, Inc. | Apparatus and method for delivering therapeutic and diagnostic agents |
| US7147633B2 (en) | 1999-06-02 | 2006-12-12 | Boston Scientific Scimed, Inc. | Method and apparatus for treatment of atrial fibrillation |
| US7196066B1 (en) | 1999-11-03 | 2007-03-27 | Powderject Vaccines, Inc. | DNA-vaccines based on constructs derived from the genomes of human and animal pathogens |
| JP2004509914A (ja) | 2000-09-28 | 2004-04-02 | カイロン コーポレイション | 微粒子組成物およびその製造方法 |
| EP1372708B1 (en) | 2001-02-13 | 2008-06-18 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF THE ARMY | Vaccine for transcutaneous immunization against travellers' diarrhoea |
| GB0103620D0 (en) * | 2001-02-14 | 2001-03-28 | Prometic Biosciences Ltd | Sterile composition and its preparation |
| PT1631264E (pt) | 2003-06-02 | 2009-11-03 | Novartis Vaccines & Diagnostic | Composições imunogénicas à base de micropartículas biodegradáveis que compreendem um toxóide de difteria e do tétano |
| EP1671655A4 (en) * | 2003-08-29 | 2009-08-12 | Anges Mg Inc | GENE THERAPY FOR SKIN DISEASE USING NEEDLE-FREE SYRINGE |
| US9017697B2 (en) | 2006-10-12 | 2015-04-28 | The University Of Queensland | Compositions and methods for modulating immune responses |
| DE102007004855B4 (de) * | 2007-01-31 | 2014-03-27 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vorrichtung und Verfahren zur Deposition von biologischem Material in einem Zielsubstrat |
| EP2612868B1 (en) | 2007-11-01 | 2018-08-15 | Astellas Pharma Inc. | Immunosuppressive polypeptides and nucleic acids |
| CA2816529A1 (en) | 2010-11-01 | 2012-05-10 | University Of Technology, Sydney | Immune-modulating agents and uses therefor |
| JP2025523481A (ja) | 2022-07-01 | 2025-07-23 | レセンスメディカル、インコーポレイテッド | 組成物が冷媒とともにスプレーされることになるモジュール |
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| WO1994023738A1 (en) * | 1993-04-19 | 1994-10-27 | Medisorb Technologies International L.P. | Encapsulation of nucleic acids with conjugates that facilitate and target cellular uptake and gene expression |
| GB9612629D0 (en) * | 1996-06-17 | 1996-08-21 | Oxford Biosciences Ltd | Method for providing dense particle compositions for use in transdermal particle delivery |
-
1996
- 1996-09-11 GB GBGB9619002.0A patent/GB9619002D0/en active Pending
-
1997
- 1997-09-11 DE DE69731646T patent/DE69731646T2/de not_active Expired - Fee Related
- 1997-09-11 EP EP97919142A patent/EP0928190B1/en not_active Expired - Lifetime
- 1997-09-11 JP JP10513388A patent/JP2001500858A/ja not_active Ceased
- 1997-09-11 AU AU43079/97A patent/AU4307997A/en not_active Abandoned
- 1997-09-11 ES ES97919142T patent/ES2234016T3/es not_active Expired - Lifetime
- 1997-09-11 WO PCT/GB1997/002478 patent/WO1998010750A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| GB9619002D0 (en) | 1996-10-23 |
| EP0928190B1 (en) | 2004-11-17 |
| EP0928190A2 (en) | 1999-07-14 |
| DE69731646D1 (de) | 2004-12-23 |
| JP2001500858A (ja) | 2001-01-23 |
| AU4307997A (en) | 1998-04-02 |
| WO1998010750A3 (en) | 1998-06-25 |
| WO1998010750A2 (en) | 1998-03-19 |
| ES2234016T3 (es) | 2005-06-16 |
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| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |