DE69731368D1 - Mittel zum schutz von nervenzellen - Google Patents

Mittel zum schutz von nervenzellen

Info

Publication number
DE69731368D1
DE69731368D1 DE69731368T DE69731368T DE69731368D1 DE 69731368 D1 DE69731368 D1 DE 69731368D1 DE 69731368 T DE69731368 T DE 69731368T DE 69731368 T DE69731368 T DE 69731368T DE 69731368 D1 DE69731368 D1 DE 69731368D1
Authority
DE
Germany
Prior art keywords
agent
nervous cells
protecting nervous
protecting
benzindole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69731368T
Other languages
English (en)
Other versions
DE69731368T2 (de
Inventor
Ichiro Yamamoto
Manabu Itoh
Masato Shimojo
Yasunobu Yumiya
Takafumi Mukaihira
Yasushige Akada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mochida Pharmaceutical Co Ltd
Original Assignee
Mochida Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co Ltd filed Critical Mochida Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69731368D1 publication Critical patent/DE69731368D1/de
Publication of DE69731368T2 publication Critical patent/DE69731368T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69731368T 1996-05-30 1997-05-29 Mittel zum schutz von nervenzellen Expired - Fee Related DE69731368T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP15898596 1996-05-30
JP15898596 1996-05-30
JP33276496 1996-11-28
JP33276496 1996-11-28
PCT/JP1997/001828 WO1997045410A1 (en) 1996-05-30 1997-05-29 Nerve cell protective agents

Publications (2)

Publication Number Publication Date
DE69731368D1 true DE69731368D1 (de) 2004-12-02
DE69731368T2 DE69731368T2 (de) 2005-03-17

Family

ID=26485930

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69731368T Expired - Fee Related DE69731368T2 (de) 1996-05-30 1997-05-29 Mittel zum schutz von nervenzellen

Country Status (8)

Country Link
US (1) US6040331A (de)
EP (1) EP0858996B1 (de)
KR (1) KR19990035883A (de)
AT (1) ATE280758T1 (de)
CA (1) CA2228268A1 (de)
DE (1) DE69731368T2 (de)
TW (1) TW430660B (de)
WO (1) WO1997045410A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9908165A (pt) * 1998-02-23 2000-10-31 Univ South Alabama Processos de prevenção de um citotóxico de proteìna beta amilóide em células, de tratamento de uma fibrilogênica em um sujeito humano, de diminuição da oxidação em uma amostra biológica e de tratamento de doenças ou outros quadros em que radicais livres e/ou tensão oxidativa desempenham um papel, e, uso de ácido indol-3-propiÈnico ou um seu sal ou éster.
US8722668B2 (en) * 1998-12-23 2014-05-13 Daryl W. Hochman Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders
US7214711B2 (en) * 1998-12-23 2007-05-08 Neurotherapeutics Pharma Llc Method of treating migraine headache without aura
US20060025387A1 (en) * 1998-12-23 2006-02-02 Cytoscan Sciences Llc Compositions and methods for the treatment of disorders of the central and peripheral nervous systems
US8008283B2 (en) * 1998-12-23 2011-08-30 Neurotherapeutics Pharma, Inc. Methods and compositions for the treatment of neuropsychiatric disorders
WO2000056711A1 (en) * 1999-03-23 2000-09-28 Sumitomo Pharmaceuticals Co., Ltd. Tricyclic indole-2-carboxylic acid compound used as nmda receptor antagonist
US6906096B2 (en) * 2002-06-28 2005-06-14 Irm Llc 4,7-Disubstituted indoles and methods of making
US7781478B2 (en) 2004-07-14 2010-08-24 Ptc Therapeutics, Inc. Methods for treating hepatitis C
JP5132554B2 (ja) * 2005-07-14 2013-01-30 アイアールエム・リミテッド・ライアビリティ・カンパニー Ｔｐｏ模倣剤としてのヘテロ四環化合物
CA2622571A1 (en) * 2005-09-15 2007-03-22 Painceptor Pharma Corporation Methods of modulating neurotrophin-mediated activity
WO2007047447A2 (en) * 2005-10-17 2007-04-26 Neurotherapeutics Pharma, Inc. Diuretic-like compound analogs useful for regulation of central nervous system disorders
US20100172909A1 (en) * 2005-10-24 2010-07-08 Masahiro Nishibori Cerebral edema suppressant
CN105636445B (zh) 2013-10-17 2018-12-07 美国陶氏益农公司 制备杀虫化合物的方法
WO2015058028A1 (en) 2013-10-17 2015-04-23 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
CN105636443A (zh) 2013-10-17 2016-06-01 美国陶氏益农公司 制备杀虫化合物的方法
WO2015058022A1 (en) 2013-10-17 2015-04-23 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
KR20160074542A (ko) 2013-10-17 2016-06-28 다우 아그로사이언시즈 엘엘씨 살충성 화합물의 제조 방법
CA2925873A1 (en) 2013-10-17 2015-04-23 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
MX2016004940A (es) 2013-10-17 2016-06-28 Dow Agrosciences Llc Proceso para la preparacion de compuestos plaguicidas.
CN106488908A (zh) 2014-07-31 2017-03-08 美国陶氏益农公司 制备3‑(3‑氯‑1h‑吡唑‑1‑基)吡啶的方法
WO2016018442A1 (en) 2014-07-31 2016-02-04 Dow Agrosciences Llc Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
CA2954631A1 (en) 2014-07-31 2016-02-04 Dow Agrosciences Llc Process for the preparation of 3-(3-chloro-1h-pyrazol-1-yl)pyridine
EP3183238A4 (de) 2014-08-19 2018-01-10 Dow AgroSciences LLC Verfahren zur herstellung von 3(-3-chlor-1h-pyrazol-1-yl)pyridin
EP3191455A4 (de) 2014-09-12 2018-01-24 Dow AgroSciences LLC Verfahren zur herstellung von 3(-3-chlor-1h-pyrazol-1-yl)pyridin
US20160332962A1 (en) * 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
CN110139853B (zh) 2016-12-29 2023-06-16 美国陶氏益农公司 用于制备杀有害生物化合物的方法
WO2018125817A1 (en) 2016-12-29 2018-07-05 Dow Agrosciences Llc Processes for the preparation of pesticidal compounds
EP3983340B1 (de) * 2019-06-12 2023-08-02 Nouryon Chemicals International B.V. Verfahren zur isolierung von carbonsäure aus einem wässrigen seitenstrom
EP3983368B1 (de) 2019-06-12 2023-08-02 Nouryon Chemicals International B.V. Verfahren zur herstellung von diacylperoxiden
HUE063796T2 (hu) 2019-06-12 2024-01-28 Nouryon Chemicals Int Bv Eljárás diacil-peroxidok elõállítására

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3346573A1 (de) * 1983-12-23 1985-07-04 Troponwerke GmbH & Co KG, 5000 Köln 1,3,4,5-tetrahydrobenz(c,d)indole, ein verfahren zu ihrer herstellung und ihre verwendung
DE3525564A1 (de) * 1985-07-15 1987-02-05 Schering Ag Tricyclische verbindungen mit indolstruktur, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
DE3718892A1 (de) * 1987-06-05 1988-12-22 Bayer Ag Polyhydrobenz(c,d)indol-sulfonamide
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5039820A (en) * 1990-02-26 1991-08-13 Eli Lilly And Company 4-amino-6-iodo-hexahydrobenz(cd)indoles
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
AU675645B2 (en) * 1992-04-27 1997-02-13 Mochida Pharmaceutical Co., Ltd. Tricyclic compound having antiallergic effect
JPH07188166A (ja) * 1993-11-17 1995-07-25 Sumitomo Pharmaceut Co Ltd 三環性インドール−２−カルボン酸誘導体
TW280819B (de) * 1993-11-17 1996-07-11 Sumitomo Pharma
FR2732964B1 (fr) * 1995-04-14 1997-05-16 Adir Nouveaux amides tricycliques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
WO1997045410A1 (en) 1997-12-04
EP0858996B1 (de) 2004-10-27
TW430660B (en) 2001-04-21
EP0858996A4 (de) 2001-03-21
DE69731368T2 (de) 2005-03-17
KR19990035883A (ko) 1999-05-25
US6040331A (en) 2000-03-21
CA2228268A1 (en) 1997-12-04
EP0858996A1 (de) 1998-08-19
ATE280758T1 (de) 2004-11-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee