DE69711943T2 - Methode zur geschlechtsbestimmung von vögeln in ovo - Google Patents

Methode zur geschlechtsbestimmung von vögeln in ovo

Info

Publication number
DE69711943T2
DE69711943T2 DE69711943T DE69711943T DE69711943T2 DE 69711943 T2 DE69711943 T2 DE 69711943T2 DE 69711943 T DE69711943 T DE 69711943T DE 69711943 T DE69711943 T DE 69711943T DE 69711943 T2 DE69711943 T2 DE 69711943T2
Authority
DE
Germany
Prior art keywords
ovo
sex
bird
gender
birds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69711943T
Other languages
English (en)
Other versions
DE69711943D1 (de
Inventor
V Phelps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Embrex LLC
Original Assignee
Embrex LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Embrex LLC filed Critical Embrex LLC
Publication of DE69711943D1 publication Critical patent/DE69711943D1/de
Application granted granted Critical
Publication of DE69711943T2 publication Critical patent/DE69711943T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K43/00—Testing, sorting or cleaning eggs ; Conveying devices ; Pick-up devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/465—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from birds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y10S530/852—Sperm
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/85—Reproductive organs or embryos
    • Y10S530/852—Sperm
    • Y10S530/853—Ovary; eggs; embryos
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Catching Or Destruction (AREA)
  • Fertilizers (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Farming Of Fish And Shellfish (AREA)
DE69711943T 1996-10-04 1997-10-03 Methode zur geschlechtsbestimmung von vögeln in ovo Expired - Lifetime DE69711943T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2700096P 1996-10-04 1996-10-04
PCT/US1997/018251 WO1998014781A1 (en) 1996-10-04 1997-10-03 Method of sorting birds in ovo

Publications (2)

Publication Number Publication Date
DE69711943D1 DE69711943D1 (de) 2002-05-16
DE69711943T2 true DE69711943T2 (de) 2002-11-14

Family

ID=21835085

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69711943T Expired - Lifetime DE69711943T2 (de) 1996-10-04 1997-10-03 Methode zur geschlechtsbestimmung von vögeln in ovo

Country Status (16)

Country Link
US (2) US6506570B1 (de)
EP (1) EP1021717B1 (de)
JP (1) JP3293834B2 (de)
KR (1) KR100359405B1 (de)
CN (1) CN1165763C (de)
AT (1) ATE216081T1 (de)
AU (1) AU728248B2 (de)
BR (1) BRPI9712485B1 (de)
CA (1) CA2264714C (de)
DE (1) DE69711943T2 (de)
DK (1) DK1021717T3 (de)
EA (1) EA000734B1 (de)
ES (1) ES2175374T3 (de)
ID (1) ID21888A (de)
IL (1) IL127931A (de)
WO (1) WO1998014781A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007013107A1 (de) * 2007-03-15 2008-09-18 Friedrich-Schiller-Universität Jena Verfahren zur Bestimmung des Gschlechts von Vögeln
EP2336751A1 (de) 2009-12-16 2011-06-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Bestimmung des Geschlechts an Vogeleiern
DE102012023947A1 (de) 2012-12-03 2014-06-05 Institut für Photonische Technologien e.V. (IPHT) Verfahren und Anordnung zur nichtinvasiven, zerstörungsfreien Identifikation molekülspezifischer und/oder biologischer Eigenschaften einer inneren Struktur eines biologischen Untersuchungsobjektes durch eine optisch undurchlässige Barriere hindurch

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2175374T3 (es) * 1996-10-04 2002-11-16 Embrex Inc Procedimiento para determinar el sexo de aves in ovo.
EP1304030A3 (de) 1998-01-12 2003-05-02 Embrex Inc. Vorrichtung zur automatisierten in-ovo Injektion
UY25347A1 (es) 1998-01-12 1999-05-14 Embrex Inc Procedimiento de inyeccion multiple para el tratamiento de embriones aviarios in ovo, y aparato automatizado para la inyeccion in ovo.
US6244214B1 (en) * 1999-01-06 2001-06-12 Embrex, Inc. Concurrent in ovo injection and detection method and apparatus
US7041439B2 (en) 2001-04-17 2006-05-09 Embrex, Inc. Methods and apparatus for selectively processing eggs having identified characteristics
GB0220553D0 (en) * 2002-09-04 2002-10-09 Reeves Sidney J Method andapparatus for determining the viability of eggs
GB0109765D0 (en) 2001-04-20 2001-06-13 Reeves Sidney J Apparatus and method for determining the viability of eggs
US7289196B2 (en) 2001-04-20 2007-10-30 Sidney James Reeves Method and apparatus for determining the viability of eggs
CA2445162C (en) * 2001-04-23 2011-04-05 Lifesensors, Inc. Estrogen dependent transactivation system for gender sorting in avian species
JP4128791B2 (ja) * 2002-03-27 2008-07-30 株式会社堀内 有精卵の雌雄鑑別技術
US6860225B2 (en) * 2002-05-06 2005-03-01 Embrex, Inc. Methods and apparatus for identifying live eggs by detecting embryo heart rate and/or motion
MX2007014096A (es) * 2005-05-11 2008-02-07 Embrex Inc Metodos competitivos de inmunoensayos de particulas que utilizan microscopia de fluorescencia.
US7861673B2 (en) * 2006-04-11 2011-01-04 Life-Science Innovations, Llc Egg incubation transport system and methods regarding same
US9435732B2 (en) * 2009-06-25 2016-09-06 Yissum Research Development Of The Hebrew University Of Jerusalem Ltd. Hyperspectral identification of egg fertility and gender
US9239321B2 (en) * 2010-03-24 2016-01-19 Fps Food Processing Systems, B.V. Advanced egg breaking system
WO2014021715A2 (en) * 2012-07-30 2014-02-06 Bruins Wouter Sebastiaan Gender, viability and/or developmental stage determination of avian embryos in ovo
CN109566469B (zh) * 2012-12-11 2021-10-22 昕诺飞北美公司 使用光控制卵生胚胎的性别
DE102013205426A1 (de) * 2013-03-27 2014-10-16 Siemens Aktiengesellschaft Verfahren zum Bestimmen des Geschlechts eines Embryos in einem Ei
US9395346B2 (en) 2013-11-18 2016-07-19 Zoetis Services Llc Non-contact egg identification system for determining egg viability, and associated method
US9513270B2 (en) 2013-11-18 2016-12-06 Zoetis Services Llc Non-contact egg identification system for determining egg viability using transmission spectroscopy, and associated method
DE102014010150A1 (de) 2014-07-04 2016-01-07 Technische Universität Dresden Verfahren und Vorrichtung zur Raman-spektroskopischen in-ovo Geschlechtsbestimmung von befruchteten und bebrüteten Vogeleiern
CN104698173B (zh) * 2015-02-26 2016-08-17 武汉市畜牧兽医科学研究所 一种鸭胚早期性别鉴定方法及专用试剂盒
CN105191831B (zh) * 2015-09-25 2017-12-12 中国农业大学 一种鸡胚蛋性别鉴定方法
DE102015226490A1 (de) * 2015-12-22 2017-06-22 Universität Leipzig Verfahren zur in ovo Geschlechterbestimmung von Küken
DE102016004051B3 (de) 2016-04-04 2017-07-27 Technische Universität Dresden Verfahren und Vorrichtung zur optischen in-ovo Geschlechtsbestimmung von befruchteten und bebrüteten Vogeleiern
PL3465222T3 (pl) 2016-05-24 2021-09-27 In Ovo Holding B.V. Sposób i układ nieniszczącego określania płci ptactwa drobiu in ovo
WO2018154389A1 (en) 2017-02-23 2018-08-30 Ryshens Ltd. Devices and methods for determining analytes
EP3648585A1 (de) * 2017-07-06 2020-05-13 Seleggt GmbH Verfahren zum bebrüten von eiern
WO2019007520A1 (en) 2017-07-06 2019-01-10 Seleggt Gmbh PROCESS FOR PRODUCTION OF CHICKEN USING SEXING OF CHICKEN EMBRYOS
EP3483619A1 (de) * 2017-11-13 2019-05-15 Technische Universität München Automatisierte nicht-invasive bestimmung des geschlechts eines embryos und der fertilität eines vogeleis
CN111698903B (zh) 2018-02-07 2022-12-27 塞莱格特有限公司 用于对蛋进行采样的方法
FR3095519B1 (fr) 2019-04-25 2021-03-26 Commissariat Energie Atomique Procédé non-invasif de détermination du genre d'un œuf
NL2024700B1 (en) * 2020-01-17 2021-09-08 In Ovo Holding B V Egg Sampling Device
NL2026004B1 (en) 2020-07-05 2022-03-11 In Ovo Holding B V Egg Determining Method and Device
KR102632163B1 (ko) 2022-04-13 2024-02-01 오보젠 주식회사 가금류 알(卵)의 암수 검사 및 선별장치 그리고 이를 이용한 선별방법
FR3135527A1 (fr) 2022-05-12 2023-11-17 Commissariat A L'energie Atomique Et Aux Energies Alternatives Procédé et système de détermination d'une caractéristique d'un œuf d'un être vivant
WO2024094751A1 (en) 2022-11-03 2024-05-10 Seleggt Gmbh Method for determining the gender of a chick

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FR2441378A1 (fr) * 1978-11-15 1980-06-13 Paris Organo Chimie Lab Procede de determination du sexe de l'enfant avant sa naissance
FR2497576B1 (fr) 1981-01-06 1985-06-28 Agronomique Inst Nat Rech Procede de reconnaissance des femelles en vitellogenese chez les animaux ovipares par un test d'immunoagglutination
JPS63216416A (ja) 1987-03-06 1988-09-08 日清製粉株式会社 家畜の繁殖方法
WO1990009188A1 (en) * 1989-02-08 1990-08-23 The Texas A&M University System In ovo administration of growth factors alters physiological development and response of poultry
NZ236440A (en) 1989-12-15 1993-07-27 Merck & Co Inc Reversal of sexual phenotype in poultry using an inhibitor of steroid biotransformation and/or aromatase inhibitor, poultry produced by this process
US5648468A (en) * 1990-03-09 1997-07-15 Spaulding; Glenn F. Process for identifying sex associated egg proteins and methods for increasing the probability that the avian offspring will be the desired sex
US5508165A (en) * 1990-09-21 1996-04-16 Zoogen, Inc. Avian sex determination probe
JPH04204238A (ja) 1990-11-30 1992-07-24 Masayasu Wada 鳥類の染色体標本及びその性別判定法
US5679514A (en) 1992-12-31 1997-10-21 Texas Tech University Method for determining the sex of birds
US5679513A (en) 1992-12-31 1997-10-21 Texas Tech University Method for diagnosing ratites
AU1935595A (en) 1994-02-28 1995-09-11 Agritech Technologies, Ltd. Methods of determining the gender of poultry
JPH08149982A (ja) 1994-11-30 1996-06-11 Ito Ham Kk 鳥類のアロマターゼ関連ｄｎａ
GB9511439D0 (en) * 1995-06-06 1995-08-02 Isis Innovation Gene product and method
CA2183012A1 (en) 1995-08-11 1997-02-12 Stan R. Blecher Method for identifying sex specific and species specific molecules, molecules identified using the method, and uses of the molecules
AUPO060996A0 (en) 1996-06-21 1996-07-18 University Of Melbourne, The Sexing gene
ES2175374T3 (es) * 1996-10-04 2002-11-16 Embrex Inc Procedimiento para determinar el sexo de aves in ovo.

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102007013107A1 (de) * 2007-03-15 2008-09-18 Friedrich-Schiller-Universität Jena Verfahren zur Bestimmung des Gschlechts von Vögeln
DE102007013107B4 (de) * 2007-03-15 2011-02-10 Friedrich-Schiller-Universität Jena Verfahren zur Bestimmung des Geschlechts von Vögeln
EP2336751A1 (de) 2009-12-16 2011-06-22 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Bestimmung des Geschlechts an Vogeleiern
US8364247B2 (en) 2009-12-16 2013-01-29 Fraunhofer-Gesellschaft Zur Foerderung Der Angwandten Forschung E.V. Methods for determining the sex of birds' eggs
DE102012023947A1 (de) 2012-12-03 2014-06-05 Institut für Photonische Technologien e.V. (IPHT) Verfahren und Anordnung zur nichtinvasiven, zerstörungsfreien Identifikation molekülspezifischer und/oder biologischer Eigenschaften einer inneren Struktur eines biologischen Untersuchungsobjektes durch eine optisch undurchlässige Barriere hindurch
WO2014086335A1 (de) 2012-12-03 2014-06-12 Institut Für Photonische Technologien E.V. Verfahren und anordnung zur nichtinvasiven, zerstörungsfreien identifikation molekülspezifischer und/oder biologischer eigenschaften einer inneren struktur eines biologischen untersuchungsobjektes durch eine optisch undurchlässige barriere hindurch

Also Published As

Publication number Publication date
DE69711943D1 (de) 2002-05-16
US6989238B2 (en) 2006-01-24
US6506570B1 (en) 2003-01-14
DK1021717T3 (da) 2002-07-08
KR100359405B1 (ko) 2002-11-04
EA000734B1 (ru) 2000-02-28
BRPI9712485B1 (pt) 2017-05-30
AU4980297A (en) 1998-04-24
US20030096319A1 (en) 2003-05-22
EP1021717B1 (de) 2002-04-10
WO1998014781A1 (en) 1998-04-09
KR20000029995A (ko) 2000-05-25
CA2264714C (en) 2004-01-20
ID21888A (id) 1999-08-05
IL127931A (en) 2001-01-28
EA199900343A1 (ru) 1999-08-26
CA2264714A1 (en) 1998-04-09
ATE216081T1 (de) 2002-04-15
EP1021717A1 (de) 2000-07-26
JP2001500622A (ja) 2001-01-16
AU728248B2 (en) 2001-01-04
CN1232545A (zh) 1999-10-20
ES2175374T3 (es) 2002-11-16
CN1165763C (zh) 2004-09-08
BR9712485A (pt) 1999-10-19
IL127931A0 (en) 1999-11-30
JP3293834B2 (ja) 2002-06-17

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