DE69711610T2 - System, verfahren und vorrichtung zur kontrollierten freisetzung eines produkts - Google Patents
System, verfahren und vorrichtung zur kontrollierten freisetzung eines produktsInfo
- Publication number
- DE69711610T2 DE69711610T2 DE69711610T DE69711610T DE69711610T2 DE 69711610 T2 DE69711610 T2 DE 69711610T2 DE 69711610 T DE69711610 T DE 69711610T DE 69711610 T DE69711610 T DE 69711610T DE 69711610 T2 DE69711610 T2 DE 69711610T2
- Authority
- DE
- Germany
- Prior art keywords
- container
- closure
- ingredient
- interior
- closure plug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title claims description 39
- 238000013270 controlled release Methods 0.000 title claims 3
- 239000004615 ingredient Substances 0.000 claims description 49
- 239000000463 material Substances 0.000 claims description 19
- 238000002156 mixing Methods 0.000 claims description 14
- 230000008569 process Effects 0.000 claims description 14
- 230000001954 sterilising effect Effects 0.000 claims description 13
- 238000004659 sterilization and disinfection Methods 0.000 claims description 13
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 10
- 239000008121 dextrose Substances 0.000 claims description 10
- 239000000872 buffer Substances 0.000 claims description 9
- 238000000502 dialysis Methods 0.000 claims description 9
- 238000010438 heat treatment Methods 0.000 claims description 9
- 238000001816 cooling Methods 0.000 claims description 8
- 238000007789 sealing Methods 0.000 claims description 5
- 229920000642 polymer Polymers 0.000 description 26
- 239000000243 solution Substances 0.000 description 22
- 239000011257 shell material Substances 0.000 description 19
- 239000011162 core material Substances 0.000 description 18
- 229920000092 linear low density polyethylene Polymers 0.000 description 14
- 239000004707 linear low-density polyethylene Substances 0.000 description 14
- 239000000126 substance Substances 0.000 description 13
- 230000008901 benefit Effects 0.000 description 10
- 230000008859 change Effects 0.000 description 10
- 239000004743 Polypropylene Substances 0.000 description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- 238000000926 separation method Methods 0.000 description 8
- 239000000203 mixture Substances 0.000 description 7
- 239000004698 Polyethylene Substances 0.000 description 6
- 235000013361 beverage Nutrition 0.000 description 6
- 238000010586 diagram Methods 0.000 description 6
- 239000003814 drug Substances 0.000 description 6
- 229940079593 drug Drugs 0.000 description 6
- 230000002706 hydrostatic effect Effects 0.000 description 6
- 238000010276 construction Methods 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
- 230000008602 contraction Effects 0.000 description 4
- 238000013461 design Methods 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000004048 modification Effects 0.000 description 4
- 238000012986 modification Methods 0.000 description 4
- 230000008961 swelling Effects 0.000 description 4
- 239000007853 buffer solution Substances 0.000 description 3
- 239000002775 capsule Substances 0.000 description 3
- 238000007906 compression Methods 0.000 description 3
- 235000013305 food Nutrition 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 238000002844 melting Methods 0.000 description 3
- 230000008018 melting Effects 0.000 description 3
- -1 polypropylene Polymers 0.000 description 3
- 230000007704 transition Effects 0.000 description 3
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 238000001994 activation Methods 0.000 description 2
- 230000006399 behavior Effects 0.000 description 2
- 230000006835 compression Effects 0.000 description 2
- 238000002425 crystallisation Methods 0.000 description 2
- 230000008025 crystallization Effects 0.000 description 2
- 238000004090 dissolution Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 229920001971 elastomer Polymers 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 229960002897 heparin Drugs 0.000 description 2
- 229920000669 heparin Polymers 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- 239000002861 polymer material Substances 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- BQCIDUSAKPWEOX-UHFFFAOYSA-N 1,1-Difluoroethene Chemical compound FC(F)=C BQCIDUSAKPWEOX-UHFFFAOYSA-N 0.000 description 1
- 229920000219 Ethylene vinyl alcohol Polymers 0.000 description 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 239000004642 Polyimide Substances 0.000 description 1
- 239000004809 Teflon Substances 0.000 description 1
- 229920006362 Teflon® Polymers 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 229940044683 chemotherapy drug Drugs 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 239000000385 dialysis solution Substances 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- UFRKOOWSQGXVKV-UHFFFAOYSA-N ethene;ethenol Chemical compound C=C.OC=C UFRKOOWSQGXVKV-UHFFFAOYSA-N 0.000 description 1
- 239000004715 ethylene vinyl alcohol Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 235000012041 food component Nutrition 0.000 description 1
- 239000005417 food ingredient Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000009477 glass transition Effects 0.000 description 1
- 229960001031 glucose Drugs 0.000 description 1
- 230000013632 homeostatic process Effects 0.000 description 1
- 239000000017 hydrogel Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 238000001990 intravenous administration Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 238000009832 plasma treatment Methods 0.000 description 1
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
- 229920002492 poly(sulfone) Polymers 0.000 description 1
- 229920000570 polyether Polymers 0.000 description 1
- 229920001721 polyimide Polymers 0.000 description 1
- 239000004926 polymethyl methacrylate Substances 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920002981 polyvinylidene fluoride Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 235000021487 ready-to-eat food Nutrition 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 229920000638 styrene acrylonitrile Polymers 0.000 description 1
- 239000011145 styrene acrylonitrile resin Substances 0.000 description 1
- 229920003051 synthetic elastomer Polymers 0.000 description 1
- 239000012815 thermoplastic material Substances 0.000 description 1
- 229920001187 thermosetting polymer Polymers 0.000 description 1
- 239000004634 thermosetting polymer Substances 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/32—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents for packaging two or more different materials which must be maintained separate prior to use in admixture
- B65D81/3216—Rigid containers disposed one within the other
- B65D81/3222—Rigid containers disposed one within the other with additional means facilitating admixture
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/1842—Ambient condition change responsive
- Y10T137/1939—Atmospheric
- Y10T137/1963—Temperature
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/1842—Ambient condition change responsive
- Y10T137/1939—Atmospheric
- Y10T137/2012—Pressure
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- External Artificial Organs (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/739,243 US5865308A (en) | 1996-10-29 | 1996-10-29 | System, method and device for controllably releasing a product |
| PCT/US1997/019423 WO1998018425A1 (en) | 1996-10-29 | 1997-10-28 | A system, method and device for controllably releasing a product |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69711610D1 DE69711610D1 (de) | 2002-05-08 |
| DE69711610T2 true DE69711610T2 (de) | 2002-11-28 |
Family
ID=24971433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69711610T Expired - Lifetime DE69711610T2 (de) | 1996-10-29 | 1997-10-28 | System, verfahren und vorrichtung zur kontrollierten freisetzung eines produkts |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5865308A (enExample) |
| EP (1) | EP0891179B1 (enExample) |
| JP (1) | JP4132079B2 (enExample) |
| KR (1) | KR19990076875A (enExample) |
| BR (1) | BR9706898A (enExample) |
| CA (1) | CA2241076A1 (enExample) |
| DE (1) | DE69711610T2 (enExample) |
| ES (1) | ES2175375T3 (enExample) |
| MX (1) | MX9805191A (enExample) |
| WO (1) | WO1998018425A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6615856B2 (en) * | 2000-08-04 | 2003-09-09 | Biomicro Systems, Inc. | Remote valving for microfluidic flow control |
| DE20106836U1 (de) * | 2001-04-19 | 2001-09-27 | RPC Bramlage GmbH, 49393 Lohne | Einsatz für unter Druck stehende Flüssigkeitsbehälter, insbesondere Getränkebehälter |
| DE20119197U1 (de) * | 2001-11-29 | 2003-01-16 | RPC Bramlage GmbH, 49393 Lohne | Einsatz für Flüssigkeitsbehälter |
| US7988679B2 (en) * | 2003-03-18 | 2011-08-02 | Navilyst Medical, Inc. | Pressure responsive slit valve assembly for a plurality of fluids and uses thereof |
| US7435236B2 (en) | 2003-06-27 | 2008-10-14 | Navilyst Medical, Inc. | Pressure actuated valve with improved biasing member |
| US7252652B2 (en) * | 2003-08-29 | 2007-08-07 | Boston Scientific Scimed, Inc. | Valved catheters including high flow rate catheters |
| US20050165364A1 (en) * | 2004-01-22 | 2005-07-28 | Dimatteo Kristian | Valved catheter to bypass connector |
| US9314608B2 (en) | 2004-01-29 | 2016-04-19 | Angiodynamics, Inc | Pressure activated safety valve with high flow slit |
| US9933079B2 (en) | 2004-01-29 | 2018-04-03 | Angiodynamics, Inc. | Stacked membrane for pressure actuated valve |
| US8034035B2 (en) | 2004-01-29 | 2011-10-11 | Navilyst Medical, Inc. | Pressure activated safety valve with high flow slit |
| US8187234B2 (en) * | 2004-01-29 | 2012-05-29 | Navilyst Medical, Inc. | Pressure activated safety valve with anti-adherent coating |
| US8328768B2 (en) * | 2005-02-11 | 2012-12-11 | Angiodynamics, Inc | Pressure activated safety valve with improved flow characteristics and durability |
| US8585660B2 (en) | 2006-01-25 | 2013-11-19 | Navilyst Medical, Inc. | Valved catheter with power injection bypass |
| US8257321B2 (en) | 2008-05-21 | 2012-09-04 | Navilyst Medical, Inc. | Pressure activated valve for high flow rate and pressure venous access applications |
| US8337470B2 (en) * | 2009-01-28 | 2012-12-25 | Angiodynamics, Inc. | Three-way valve for power injection in vascular access devices |
| US8083721B2 (en) | 2009-01-29 | 2011-12-27 | Navilyst Medical, Inc. | Power injection valve |
| US8007468B2 (en) | 2009-07-13 | 2011-08-30 | Navilyst Medical, Inc. | Method to secure an elastic component in a valve |
| US20110087093A1 (en) * | 2009-10-09 | 2011-04-14 | Navilyst Medical, Inc. | Valve configurations for implantable medical devices |
| US9895524B2 (en) | 2012-07-13 | 2018-02-20 | Angiodynamics, Inc. | Fluid bypass device for valved catheters |
| US10610678B2 (en) | 2016-08-11 | 2020-04-07 | Angiodynamics, Inc. | Bi-directional, pressure-actuated medical valve with improved fluid flow control and method of using such |
| WO2020142698A1 (en) * | 2019-01-05 | 2020-07-09 | Foremost Technologies and Products, Inc. | High pressure processing of foods and supplements |
| KR102584576B1 (ko) * | 2021-04-07 | 2023-09-27 | 황일영 | 소형 용기, 상기 소형 용기를 이용한 물질의 전달 방법 및 혼합 장치 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE482319C (de) * | 1929-09-11 | Eduard Kober | Vorrichtung zum Markieren und Abschneiden von Schlauchstraengen fuer die Herstellungvon Dichtungsringen fuer Flaschen u. dgl. | |
| US611520A (en) * | 1898-09-27 | Bottle for holding spirits or other liquids and aerated waters | ||
| US2371774A (en) * | 1943-03-10 | 1945-03-20 | William A Nosik | Pharmaceutical dispensing device |
| US2549417A (en) * | 1949-08-10 | 1951-04-17 | Frederick M Turnbull | Syringe ampoule |
| BE503143A (enExample) * | 1950-05-09 | |||
| FR1274643A (fr) * | 1960-09-13 | 1961-10-27 | Dispositif de bouchage pour flacons destinés aux préparations extemporanées | |
| US4396383A (en) * | 1981-11-09 | 1983-08-02 | Baxter Travenol Laboratories, Inc. | Multiple chamber solution container including positive test for homogenous mixture |
| US4411662A (en) * | 1982-04-06 | 1983-10-25 | Baxter Travenol Laboratories, Inc. | Sterile coupling |
| US4533347A (en) * | 1983-12-19 | 1985-08-06 | Warner-Lambert Company | Controller for a dual drug delivery system |
| US4731060A (en) * | 1986-11-17 | 1988-03-15 | Catalano Marc L | Hydrostatic float valve and intravenous system supplied therewith |
| US5176275A (en) * | 1989-03-27 | 1993-01-05 | Bowie Stuart S | Temperature release containers |
| US5201722A (en) * | 1990-09-04 | 1993-04-13 | Moorehead Robert H | Two-way outdwelling slit valving of medical liquid flow through a cannula and methods |
| US5205834A (en) * | 1990-09-04 | 1993-04-27 | Moorehead H Robert | Two-way outdwelling slit valving of medical liquid flow through a cannula and methods |
| JP3236287B2 (ja) * | 1990-11-29 | 2001-12-10 | キヤノン株式会社 | マルチプロセッサシステム |
| US5221268A (en) * | 1991-12-06 | 1993-06-22 | Block Medical, Inc. | Multiple dose control apparatus |
| WO1993019998A1 (fr) * | 1992-03-31 | 1993-10-14 | Tokai Corporation | Boite de conserve alimentaire prete a rechauffer |
| US5385545A (en) * | 1992-06-24 | 1995-01-31 | Science Incorporated | Mixing and delivery system |
| GB9316317D0 (en) * | 1993-08-06 | 1993-09-22 | Smithkline Beecham Plc | Novel container |
| GB9410493D0 (en) * | 1994-05-25 | 1994-07-13 | Metal Box Plc | Beverage container |
| FR2730218B1 (fr) * | 1995-02-06 | 1997-03-21 | Jean Marc Francois Torrollion | Dispositif pour stocker isoler un produit dans un emballage pressurise et le liberer au moment de son ouverture |
-
1996
- 1996-10-29 US US08/739,243 patent/US5865308A/en not_active Expired - Lifetime
-
1997
- 1997-10-28 EP EP97912944A patent/EP0891179B1/en not_active Expired - Lifetime
- 1997-10-28 KR KR1019980705002A patent/KR19990076875A/ko not_active Withdrawn
- 1997-10-28 CA CA002241076A patent/CA2241076A1/en not_active Abandoned
- 1997-10-28 JP JP52066898A patent/JP4132079B2/ja not_active Expired - Fee Related
- 1997-10-28 WO PCT/US1997/019423 patent/WO1998018425A1/en not_active Ceased
- 1997-10-28 DE DE69711610T patent/DE69711610T2/de not_active Expired - Lifetime
- 1997-10-28 ES ES97912944T patent/ES2175375T3/es not_active Expired - Lifetime
- 1997-10-28 BR BR9706898A patent/BR9706898A/pt not_active IP Right Cessation
-
1998
- 1998-06-25 MX MX9805191A patent/MX9805191A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998018425A1 (en) | 1998-05-07 |
| CA2241076A1 (en) | 1998-05-07 |
| US5865308A (en) | 1999-02-02 |
| JP2000504252A (ja) | 2000-04-11 |
| BR9706898A (pt) | 1999-07-20 |
| ES2175375T3 (es) | 2002-11-16 |
| KR19990076875A (ko) | 1999-10-25 |
| DE69711610D1 (de) | 2002-05-08 |
| MX9805191A (es) | 1998-10-31 |
| JP4132079B2 (ja) | 2008-08-13 |
| EP0891179A1 (en) | 1999-01-20 |
| EP0891179B1 (en) | 2002-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |