DE69708304D1 - Vernetzte copolymere auf der basis von polycarbonsäurepolymeren - Google Patents

Vernetzte copolymere auf der basis von polycarbonsäurepolymeren

Info

Publication number
DE69708304D1
DE69708304D1 DE69708304T DE69708304T DE69708304D1 DE 69708304 D1 DE69708304 D1 DE 69708304D1 DE 69708304 T DE69708304 T DE 69708304T DE 69708304 T DE69708304 T DE 69708304T DE 69708304 D1 DE69708304 D1 DE 69708304D1
Authority
DE
Germany
Prior art keywords
polycarboxylic acid
acid polymers
copolymers based
crosslinked copolymers
copolymers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69708304T
Other languages
English (en)
Other versions
DE69708304T2 (de
Inventor
Matni Nada El
Denis Labarre
Hatem Fessim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Application granted granted Critical
Publication of DE69708304D1 publication Critical patent/DE69708304D1/de
Publication of DE69708304T2 publication Critical patent/DE69708304T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0045—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Galacturonans, e.g. methyl ester of (alpha-1,4)-linked D-galacturonic acid units, i.e. pectin, or hydrolysis product of methyl ester of alpha-1,4-linked D-galacturonic acid units, i.e. pectinic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Graft Or Block Polymers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
DE69708304T 1996-08-30 1997-08-29 Vernetzte copolymere auf der basis von polycarbonsäurepolymeren Expired - Lifetime DE69708304T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9610601A FR2752843B1 (fr) 1996-08-30 1996-08-30 Copolymeres reticules a base de polymeres polycarboxyliques et leur utilisation comme support de composition pharmaceutique
PCT/FR1997/001534 WO1998008897A1 (fr) 1996-08-30 1997-08-29 Copolymeres reticules a base de polymeres polycarboxyliques

Publications (2)

Publication Number Publication Date
DE69708304D1 true DE69708304D1 (de) 2001-12-20
DE69708304T2 DE69708304T2 (de) 2002-07-25

Family

ID=9495309

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69708304T Expired - Lifetime DE69708304T2 (de) 1996-08-30 1997-08-29 Vernetzte copolymere auf der basis von polycarbonsäurepolymeren

Country Status (20)

Country Link
EP (1) EP0922071B1 (de)
JP (1) JP4162265B2 (de)
AT (1) ATE208803T1 (de)
AU (1) AU730566B2 (de)
CA (1) CA2266645C (de)
CZ (1) CZ296041B6 (de)
DE (1) DE69708304T2 (de)
DK (1) DK0922071T3 (de)
ES (1) ES2167784T3 (de)
FR (1) FR2752843B1 (de)
HU (1) HUP9903745A3 (de)
IL (1) IL128619A (de)
MY (1) MY116595A (de)
NO (1) NO311621B1 (de)
NZ (1) NZ334301A (de)
PL (1) PL193227B1 (de)
PT (1) PT922071E (de)
RU (1) RU2194055C2 (de)
WO (1) WO1998008897A1 (de)
ZA (1) ZA977671B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303735B1 (it) * 1998-11-11 2001-02-23 Falorni Italia Farmaceutici S Acidi ialuronici reticolati e loro usi medici.
IT1303738B1 (it) * 1998-11-11 2001-02-23 Aquisitio S P A Processo di reticolazione di polisaccaridi carbossilati.
US6288043B1 (en) * 1999-06-18 2001-09-11 Orquest, Inc. Injectable hyaluronate-sulfated polysaccharide conjugates
FR2799196B1 (fr) * 1999-10-04 2002-02-08 Sod Conseils Rech Applic Copolymeres reticules a base de copolymeres polycarboxyliques non reticules
KR100378109B1 (ko) * 2000-10-24 2003-03-29 주식회사 메디프렉스 소수성 다중복합 헤파린 결합체, 그의 제조방법 및 용도
KR101161459B1 (ko) * 2003-07-18 2012-07-02 도요 보세키 가부시키가이샤 아미노산 유도체 서방성 중합체, 이 중합체를 함유하는화장료 및 섬유 구조물, 및 이들의 제조방법 및 재생처리법
FR2873379B1 (fr) * 2004-07-23 2008-05-16 Jerome Asius Procede de preparation d'acide hyaluronique reticule, acide hyaluronique reticule susceptible d'etre obtenu par ledit procede, implant contenant ledit acide hyaluronique reticule, et son utilisation
GB2423252B (en) * 2005-02-18 2007-10-17 Engelhard Lyon Cross-linked polymer of carbohydrate, notably based on polysaccharides, and/or on oligosaccharides and/or on polyols
US20100273734A1 (en) * 2006-02-28 2010-10-28 Novozymes Biopolymer A/S Derivatives of Hyaluronic Acids
EP1942117A1 (de) 2006-12-29 2008-07-09 Sigea S.R.L. Derivate aus Carboxypolysacchariden
JP2011500553A (ja) * 2007-10-10 2011-01-06 ルピン・リミテッド ５−アミノサリチル酸またはその塩もしくは代謝産物の新規な結腸を標的とする調節放出性生体接着性製剤
JP5722217B2 (ja) 2008-09-02 2015-05-20 アラーガン・ホールディングス・フランス・ソシエテ・パール・アクシオン・サンプリフィエＡｌｌｅｒｇａｎ Ｈｏｌｄｉｎｇｓ Ｆｒａｎｃｅ Ｓ．Ａ．Ｓ． ヒアルロン酸および／またはその誘導体の糸、その作製方法、ならびにその使用
CZ302789B6 (cs) * 2009-11-25 2011-11-09 Zentiva, K. S. Zpusob zvýšení rozpustnosti farmaceuticky aktivních látek a cílený (kontrolovaný) transport do streva
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
EP3520827B1 (de) 2010-03-22 2022-05-25 Allergan, Inc. Vernetzte hydrogele zur weichgewebevergrösserung
CA3133676A1 (en) 2011-06-03 2012-12-06 Allergan Industrie, Sas Dermal filler compositions including antioxidants
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
FR2997014B1 (fr) 2012-10-24 2015-03-20 Teoxane Composition sterile dermo-injectable
ITUD20130119A1 (it) * 2013-09-12 2015-03-13 Limacorporate Spa Idrogel biocompatibile per uso biomedico o farmaceutico, polimero intermedio per realizzare detto idrogel biocompatibile e relativo metodo di realizzazione
ES2811269T3 (es) 2014-01-31 2021-03-11 Seikagaku Kogyo Co Ltd Agente de reticulación de diamina, cuerpo reticulado de polisacárido ácido y material médico
WO2016051219A1 (en) 2014-09-30 2016-04-07 Allergan Industrie, Sas Stable hydrogel compositions including additives
EP3386551A4 (de) * 2015-12-11 2018-10-24 The General Hospital Corporation Dextrannanopartikel zur makrophagenspezifischen bildgebung und therapie

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4026851A (en) * 1975-08-13 1977-05-31 E. I. Du Pont De Nemours And Company Acrylate polymers cured with diamines in the presence of an acid catalyst
US4663050A (en) * 1982-01-18 1987-05-05 Standard Oil Company Semipermeable membranes prepared from polymers containing adjacent, pendent carboxy groups
US4937270A (en) * 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US5017229A (en) * 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
DE3809764A1 (de) * 1988-03-23 1989-10-05 Knoll Ag Mischung aus alginaten und polyacrylaten und deren verwendung
ATE185267T1 (de) * 1990-05-04 1999-10-15 Perio Prod Ltd System zur arzneistoffabgabe im colon

Also Published As

Publication number Publication date
IL128619A0 (en) 2000-01-31
IL128619A (en) 2004-02-19
CA2266645A1 (fr) 1998-03-05
DE69708304T2 (de) 2002-07-25
HUP9903745A2 (hu) 2000-03-28
ATE208803T1 (de) 2001-11-15
PL193227B1 (pl) 2007-01-31
RU2194055C2 (ru) 2002-12-10
CZ60699A3 (cs) 2000-06-14
WO1998008897A1 (fr) 1998-03-05
CA2266645C (fr) 2008-03-18
AU730566B2 (en) 2001-03-08
JP2001501228A (ja) 2001-01-30
FR2752843A1 (fr) 1998-03-06
DK0922071T3 (da) 2002-03-11
MY116595A (en) 2004-02-28
JP4162265B2 (ja) 2008-10-08
NO311621B1 (no) 2001-12-17
ZA977671B (en) 1998-02-23
AU4121597A (en) 1998-03-19
NO990935D0 (no) 1999-02-26
NO990935L (no) 1999-04-15
ES2167784T3 (es) 2002-05-16
EP0922071A1 (de) 1999-06-16
EP0922071B1 (de) 2001-11-14
HUP9903745A3 (en) 2001-03-28
CZ296041B6 (cs) 2005-12-14
FR2752843B1 (fr) 1998-10-16
PT922071E (pt) 2002-05-31
PL331848A1 (en) 1999-08-16
NZ334301A (en) 2000-06-23

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Legal Events

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8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: IPSEN PHARMA S.A.S., BOULOGNE-BILLANCOURT, FR