IL128619A0 - Polycarboxylic based cross-linked copolymers - Google Patents

Polycarboxylic based cross-linked copolymers

Info

Publication number
IL128619A0
IL128619A0 IL12861997A IL12861997A IL128619A0 IL 128619 A0 IL128619 A0 IL 128619A0 IL 12861997 A IL12861997 A IL 12861997A IL 12861997 A IL12861997 A IL 12861997A IL 128619 A0 IL128619 A0 IL 128619A0
Authority
IL
Israel
Prior art keywords
based cross
polycarboxylic
linked copolymers
copolymers
linked
Prior art date
Application number
IL12861997A
Other versions
IL128619A (en
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of IL128619A0 publication Critical patent/IL128619A0/en
Publication of IL128619A publication Critical patent/IL128619A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0045—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Galacturonans, e.g. methyl ester of (alpha-1,4)-linked D-galacturonic acid units, i.e. pectin, or hydrolysis product of methyl ester of alpha-1,4-linked D-galacturonic acid units, i.e. pectinic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
    • C08F8/32—Introducing nitrogen atoms or nitrogen-containing groups by reaction with amines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Graft Or Block Polymers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

The invention concerns cross-linked copolymers with a base of non cross-linked polycarboxylic polymers, said copolymers containing at least one polycarboxylic polysaccharide. The invention also concerns a method for preparing these copolymers and their use in particular as support in pharmaceutical compositions.
IL12861997A 1996-08-30 1997-08-29 Cross-linked copolymers based on non-crosslinked polycarboxylic polymers, a process for their preparation and pharmaceutical compositions for sustained released comprising said copolymers IL128619A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9610601A FR2752843B1 (en) 1996-08-30 1996-08-30 CROSSLINKED COPOLYMERS BASED ON POLYCARBOXYLIC POLYMERS AND THEIR USE AS SUPPORTS OF PHARMACEUTICAL COMPOSITIONS
PCT/FR1997/001534 WO1998008897A1 (en) 1996-08-30 1997-08-29 Polycarboxylic based cross-linked copolymers

Publications (2)

Publication Number Publication Date
IL128619A0 true IL128619A0 (en) 2000-01-31
IL128619A IL128619A (en) 2004-02-19

Family

ID=9495309

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12861997A IL128619A (en) 1996-08-30 1997-08-29 Cross-linked copolymers based on non-crosslinked polycarboxylic polymers, a process for their preparation and pharmaceutical compositions for sustained released comprising said copolymers

Country Status (20)

Country Link
EP (1) EP0922071B1 (en)
JP (1) JP4162265B2 (en)
AT (1) ATE208803T1 (en)
AU (1) AU730566B2 (en)
CA (1) CA2266645C (en)
CZ (1) CZ296041B6 (en)
DE (1) DE69708304T2 (en)
DK (1) DK0922071T3 (en)
ES (1) ES2167784T3 (en)
FR (1) FR2752843B1 (en)
HU (1) HUP9903745A3 (en)
IL (1) IL128619A (en)
MY (1) MY116595A (en)
NO (1) NO311621B1 (en)
NZ (1) NZ334301A (en)
PL (1) PL193227B1 (en)
PT (1) PT922071E (en)
RU (1) RU2194055C2 (en)
WO (1) WO1998008897A1 (en)
ZA (1) ZA977671B (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1303738B1 (en) * 1998-11-11 2001-02-23 Aquisitio S P A CARBOXYLATE POLYSACCHARIDE CROSS-LINKING PROCESS.
IT1303735B1 (en) * 1998-11-11 2001-02-23 Falorni Italia Farmaceutici S CROSS-LINKED HYALURONIC ACIDS AND THEIR MEDICAL USES.
US6288043B1 (en) * 1999-06-18 2001-09-11 Orquest, Inc. Injectable hyaluronate-sulfated polysaccharide conjugates
FR2799196B1 (en) 1999-10-04 2002-02-08 Sod Conseils Rech Applic CROSSLINKED COPOLYMERS BASED ON NON-CROSSLINKED POLYCARBOXYLIC COPOLYMERS
KR100378109B1 (en) * 2000-10-24 2003-03-29 주식회사 메디프렉스 Hydrophobic multicomponant heparin conjugates, a preparing method and a use thereof
KR101161459B1 (en) * 2003-07-18 2012-07-02 도요 보세키 가부시키가이샤 Polymer sustainedly releasing amino acid derivative, cosmetic and fiber construct containing the polymer, method of producing the same and method of regenerating the same
FR2873379B1 (en) * 2004-07-23 2008-05-16 Jerome Asius PROCESS FOR THE PREPARATION OF RETICULATED HYALURONIC ACID, RETICULATED HYALURONIC ACID WHICH CAN BE OBTAINED BY THIS METHOD, IMPLANT CONTAINING THE RETICULATED HYALURONIC ACID, AND USE THEREOF
GB2423252B (en) * 2005-02-18 2007-10-17 Engelhard Lyon Cross-linked polymer of carbohydrate, notably based on polysaccharides, and/or on oligosaccharides and/or on polyols
JP2009528438A (en) * 2006-02-28 2009-08-06 ノボザイムス バイオポリマー アクティーゼルスカブ Hyaluronic acid derivatives
EP1942117A1 (en) * 2006-12-29 2008-07-09 Sigea S.R.L. Derivatives of acid polysaccharides
WO2009047802A2 (en) * 2007-10-10 2009-04-16 Lupin Limited Novel colon targeted modified release bioadhesive formulation of 5-amino salicylic acid or its salts and metabolites thereof
EP3184552B1 (en) 2008-09-02 2020-08-12 Tautona Group LP Threads of hyaluronic acid, methods of making thereof and uses thereof
CZ302789B6 (en) * 2009-11-25 2011-11-09 Zentiva, K. S. Method of increasing solubility of pharmaceutically active compounds and targeted (controlled) transport thereof into intestine
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
AU2011229730B2 (en) 2010-03-22 2016-01-07 Allergan, Inc. Polysaccharide and protein-polysaccharide cross-linked hydrogels for soft tissue augmentation
EP3536307B1 (en) 2011-06-03 2021-10-20 ALLERGAN Industrie, SAS Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
FR2997014B1 (en) * 2012-10-24 2015-03-20 Teoxane DERMO-INJECTABLE STERILE COMPOSITION
ITUD20130119A1 (en) * 2013-09-12 2015-03-13 Limacorporate Spa BIOCOMPATIBLE IDROGEL FOR BIOMEDICAL OR PHARMACEUTICAL USE, INTERMEDIATE POLYMER TO REALIZE THE BIOCOMPATIBLE IDROGEL AND ITS APPLICATION METHOD
US10294195B2 (en) 2014-01-31 2019-05-21 Seikagaku Corporation Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials
EP3200838B1 (en) 2014-09-30 2019-09-18 Allergan Industrie, SAS Stable hydrogel compositions including additives
US20180361000A1 (en) * 2015-12-11 2018-12-20 The General Hospital Corporation Dextran nanoparticles for macrophage specific imaging and therapy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4026851A (en) * 1975-08-13 1977-05-31 E. I. Du Pont De Nemours And Company Acrylate polymers cured with diamines in the presence of an acid catalyst
US4663050A (en) * 1982-01-18 1987-05-05 Standard Oil Company Semipermeable membranes prepared from polymers containing adjacent, pendent carboxy groups
US5017229A (en) * 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US4937270A (en) * 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
DE3809764A1 (en) * 1988-03-23 1989-10-05 Knoll Ag MIXTURE OF ALGINATES AND POLYACRYLATES AND THEIR USE
HU210497B (en) * 1990-05-04 1995-04-28 Perio Prod Ltd Process for production of modified pectin

Also Published As

Publication number Publication date
PL193227B1 (en) 2007-01-31
PT922071E (en) 2002-05-31
RU2194055C2 (en) 2002-12-10
EP0922071B1 (en) 2001-11-14
CZ60699A3 (en) 2000-06-14
JP2001501228A (en) 2001-01-30
NO990935D0 (en) 1999-02-26
DE69708304D1 (en) 2001-12-20
WO1998008897A1 (en) 1998-03-05
JP4162265B2 (en) 2008-10-08
DE69708304T2 (en) 2002-07-25
EP0922071A1 (en) 1999-06-16
CZ296041B6 (en) 2005-12-14
HUP9903745A3 (en) 2001-03-28
AU4121597A (en) 1998-03-19
CA2266645C (en) 2008-03-18
ATE208803T1 (en) 2001-11-15
HUP9903745A2 (en) 2000-03-28
NO990935L (en) 1999-04-15
ES2167784T3 (en) 2002-05-16
CA2266645A1 (en) 1998-03-05
AU730566B2 (en) 2001-03-08
MY116595A (en) 2004-02-28
PL331848A1 (en) 1999-08-16
FR2752843A1 (en) 1998-03-06
FR2752843B1 (en) 1998-10-16
NO311621B1 (en) 2001-12-17
NZ334301A (en) 2000-06-23
IL128619A (en) 2004-02-19
ZA977671B (en) 1998-02-23
DK0922071T3 (en) 2002-03-11

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Legal Events

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FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees