DE69635504D1 - Herstellung von rekombinantem Faktor VIII in Gegenwart von Liposom-ähnliche Verbindung-Zusammensetzungen - Google Patents
Herstellung von rekombinantem Faktor VIII in Gegenwart von Liposom-ähnliche Verbindung-ZusammensetzungenInfo
- Publication number
- DE69635504D1 DE69635504D1 DE69635504T DE69635504T DE69635504D1 DE 69635504 D1 DE69635504 D1 DE 69635504D1 DE 69635504 T DE69635504 T DE 69635504T DE 69635504 T DE69635504 T DE 69635504T DE 69635504 D1 DE69635504 D1 DE 69635504D1
- Authority
- DE
- Germany
- Prior art keywords
- liposome
- factor viii
- recombinant factor
- preparation
- compound compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
- C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/434,900 US5679549A (en) | 1995-05-04 | 1995-05-04 | Production of recombinant factor VIII in the presence of liposome-like substances of mixed composition |
US08/634,001 US5952198A (en) | 1995-05-04 | 1996-04-17 | Production of recombinant Factor VIII in the presence of liposome-like substances of mixed composition |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69635504D1 true DE69635504D1 (de) | 2006-01-05 |
DE69635504T2 DE69635504T2 (de) | 2006-06-14 |
Family
ID=27030345
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1996635504 Expired - Lifetime DE69635504T2 (de) | 1995-05-04 | 1996-04-25 | Herstellung von rekombinantem Faktor VIII in Gegenwart von Liposom-ähnliche Verbindung-Zusammensetzungen |
Country Status (7)
Country | Link |
---|---|
US (1) | US5952198A (de) |
EP (1) | EP0745672B1 (de) |
JP (1) | JP3996655B2 (de) |
AT (1) | ATE311447T1 (de) |
AU (1) | AU710853B2 (de) |
CA (1) | CA2175628C (de) |
DE (1) | DE69635504T2 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6200560B1 (en) * | 1998-10-20 | 2001-03-13 | Avigen, Inc. | Adeno-associated virus vectors for expression of factor VIII by target cells |
US6358703B1 (en) | 1998-12-10 | 2002-03-19 | Bayer Corporation | Expression system for factor VIII |
US8110218B2 (en) * | 2000-11-30 | 2012-02-07 | The Research Foundation Of State University Of New York | Compositions and methods for less immunogenic protein-lipid complexes |
AU2002239607A1 (en) * | 2000-11-30 | 2002-06-11 | Baxter Healthcare Corporation | Ahf associated dispersion system and method for preparation |
WO2002061036A2 (en) * | 2000-11-30 | 2002-08-08 | The Research Foundation Of State University Of New York | Method of complexing a protein by the use of a dispersed system and proteins thereof |
US7625584B2 (en) * | 2000-11-30 | 2009-12-01 | The Research Foundation Of State University Of New York | Method of complexing a protein by the use of a dispersed system and proteins thereof |
US20050221414A1 (en) * | 2004-03-31 | 2005-10-06 | Katalin Varadi | Kit for measuring the thrombin generation in a sample of a patient's blood or plasma |
EP1988101A1 (de) | 2007-05-04 | 2008-11-05 | Novo Nordisk A/S | Verbesserung von Faktor-VIII-Polypeptid-Titern in Zellkulturen |
CN104411323A (zh) * | 2012-04-24 | 2015-03-11 | 诺和诺德A/S(股份有限公司) | 适用于治疗血友病的药物组合物 |
AU2014364368A1 (en) * | 2013-12-20 | 2016-07-07 | Bio-Ess Laboratories, Llc | Media for cell culture |
JP2018023356A (ja) * | 2016-08-04 | 2018-02-15 | 三洋化成工業株式会社 | 有用物質の生産方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5198349A (en) * | 1986-01-03 | 1993-03-30 | Genetics Institute, Inc. | Method for producing factor VIII:C and analogs |
US5250421A (en) * | 1986-01-03 | 1993-10-05 | Genetics Institute, Inc. | Method for producing factor VIII:C-type proteins |
WO1987004187A1 (en) * | 1986-01-03 | 1987-07-16 | Genetics Institute, Inc. | METHOD FOR PRODUCING FACTOR VIII:c-TYPE PROTEINS |
ATE63335T1 (de) * | 1986-07-11 | 1991-05-15 | Miles Inc | Herstellung von rekombinantem protein. |
-
1996
- 1996-04-17 US US08/634,001 patent/US5952198A/en not_active Expired - Lifetime
- 1996-04-25 AT AT96106482T patent/ATE311447T1/de not_active IP Right Cessation
- 1996-04-25 EP EP19960106482 patent/EP0745672B1/de not_active Expired - Lifetime
- 1996-04-25 DE DE1996635504 patent/DE69635504T2/de not_active Expired - Lifetime
- 1996-05-01 JP JP13254696A patent/JP3996655B2/ja not_active Expired - Fee Related
- 1996-05-02 CA CA 2175628 patent/CA2175628C/en not_active Expired - Fee Related
- 1996-05-03 AU AU52071/96A patent/AU710853B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
JPH0998796A (ja) | 1997-04-15 |
DE69635504T2 (de) | 2006-06-14 |
CA2175628C (en) | 2007-02-20 |
EP0745672A2 (de) | 1996-12-04 |
AU5207196A (en) | 1996-11-28 |
JP3996655B2 (ja) | 2007-10-24 |
US5952198A (en) | 1999-09-14 |
EP0745672B1 (de) | 2005-11-30 |
ATE311447T1 (de) | 2005-12-15 |
CA2175628A1 (en) | 1996-11-05 |
AU710853B2 (en) | 1999-09-30 |
EP0745672A3 (de) | 1998-05-20 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69635504T2 (de) | Herstellung von rekombinantem Faktor VIII in Gegenwart von Liposom-ähnliche Verbindung-Zusammensetzungen | |
AU5914186A (en) | Method and composition for making lipsomes | |
EP0759694A4 (de) | Verfahren zur in-vivo abgabe therapeutischer agenzien mittels liposomen | |
GR1000247B (el) | Σταθεραι λυοφιλιωμεναι διαμορφωσεις περιεχουσαι παραγοντας αναπτυξεως. | |
ES2186792T3 (es) | Metodos de fabricar liposomas que contienen fotosensibilizantes hidro-monobenzoporfirinicos. | |
CA2318566A1 (en) | Gelled foods and process for producing the same | |
FI972366A (fi) | Lipopolyamiinit transfektoivina aineina ja niiden farmaseuttinen käyttö | |
EP0283713A3 (en) | Complexes of saponins with phospholipids and pharmaceutical and cosmetic compositions containing them | |
CA2097199A1 (en) | Preparation of prothrombin time reagents from recombinant human tissue factor and purified natural and synthetic phospholipids | |
CA2250219A1 (en) | Materials and methods for making improved liposome compositions | |
CA2270396A1 (en) | Cationic reagents for transfection | |
ES8607906A1 (es) | Procedimiento para la obtencion de composiciones farmaceuti-cas conteniendo liposomas unilamilares | |
NO20013862L (no) | Fremgangsmåte for å regulere liposomstörrelse | |
CA2079685A1 (en) | Synthetic membrane vesicles containing functionally active fusion peptides as drug delivery systems | |
DE3879803T2 (de) | Reinigung von faktor viii:c durch phospholipid-affinitaet. | |
DE69332276D1 (de) | Liposomenzusammensetzung | |
AU588994B2 (en) | Novel benzodiazepine derivatives and their preparation and use | |
ES2086802T3 (es) | Formulaciones liposomicas de principios activos y procedimiento para su preparacion. | |
AU9532198A (en) | Ribonucleoside-derivative and method for preparing the same | |
AU2255488A (en) | Lipid microemulsions for culture media | |
ES8701491A1 (es) | Procedimiento para la preparacion de substancias secas obte-nibles por liofilizacion | |
AU629445B2 (en) | Improvements in or relating to topical compositions containing 1 alpha 25-dihydroxycholecalciferol | |
ES2110980T3 (es) | Composiciones liposomicas y procedimientos para su produccion. | |
GR3036631T3 (en) | Preparation and utilisation of pure enantiomers of 8-halogen-6-hydroxyoctanoic acid, their alkyl esters and their salts with pure enantiomers of alpha-methyl-benzylamines | |
ES2126516A1 (es) | Glicoproteina para proteccion de liposomas. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |