DE69633171D1 - Mutierte luziferasen - Google Patents

Mutierte luziferasen

Info

Publication number
DE69633171D1
DE69633171D1 DE69633171T DE69633171T DE69633171D1 DE 69633171 D1 DE69633171 D1 DE 69633171D1 DE 69633171 T DE69633171 T DE 69633171T DE 69633171 T DE69633171 T DE 69633171T DE 69633171 D1 DE69633171 D1 DE 69633171D1
Authority
DE
Germany
Prior art keywords
mutted
luciferas
mutted luciferas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69633171T
Other languages
English (en)
Other versions
DE69633171T2 (de
Inventor
James Squirrell
Robin Lowe
John White
Augustus Murray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Promega Corp
Original Assignee
UK Secretary of State for Defence
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9501172.2A external-priority patent/GB9501172D0/en
Priority claimed from GBGB9508301.0A external-priority patent/GB9508301D0/en
Application filed by UK Secretary of State for Defence filed Critical UK Secretary of State for Defence
Publication of DE69633171D1 publication Critical patent/DE69633171D1/de
Application granted granted Critical
Publication of DE69633171T2 publication Critical patent/DE69633171T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0069Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE69633171T 1995-01-20 1996-01-19 Mutierte luziferasen Expired - Lifetime DE69633171T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9501172 1995-01-20
GBGB9501172.2A GB9501172D0 (en) 1995-01-20 1995-01-20 Luciferases
GB9508301 1995-04-24
GBGB9508301.0A GB9508301D0 (en) 1995-04-24 1995-04-24 Luciferases
PCT/GB1996/000099 WO1996022376A1 (en) 1995-01-20 1996-01-19 Mutant luciferases

Publications (2)

Publication Number Publication Date
DE69633171D1 true DE69633171D1 (de) 2004-09-23
DE69633171T2 DE69633171T2 (de) 2005-08-18

Family

ID=26306352

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69633171T Expired - Lifetime DE69633171T2 (de) 1995-01-20 1996-01-19 Mutierte luziferasen

Country Status (10)

Country Link
US (1) US6171808B1 (de)
EP (1) EP0804587B1 (de)
JP (1) JP4342608B2 (de)
AU (1) AU707243B2 (de)
CA (1) CA2210354C (de)
DE (1) DE69633171T2 (de)
DK (1) DK0804587T3 (de)
IN (1) IN186115B (de)
NO (1) NO322134B1 (de)
WO (1) WO1996022376A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9707486D0 (en) 1997-04-11 1997-05-28 Secr Defence Enzyme assays
EP1707621B1 (de) 1997-07-08 2009-11-18 Kikkoman Corporation Mutiertes Biolumineszenz-Protein und Verfahren zu dessen Herstellung
JP4222636B2 (ja) * 1997-07-08 2009-02-12 キッコーマン株式会社 変異型生物発光タンパク質、および変異型生物発光タンパク質の製造法
US6602677B1 (en) 1997-09-19 2003-08-05 Promega Corporation Thermostable luciferases and methods of production
EP2860252A1 (de) * 1997-09-19 2015-04-15 Promega Corporation Thermostabile Luciferasen und Verfahren zur Herstellung
GB9722481D0 (en) * 1997-10-25 1997-12-24 Secr Defence Expression system
GB9823468D0 (en) 1998-10-28 1998-12-23 Secr Defence Novel enzyme
GB9925161D0 (en) 1999-10-26 1999-12-22 Secr Defence Novel enzyme
ATE374820T1 (de) * 1999-10-26 2007-10-15 Secr Defence Mutantenluciferase
US7879540B1 (en) 2000-08-24 2011-02-01 Promega Corporation Synthetic nucleic acid molecule compositions and methods of preparation
GB0030727D0 (en) 2000-12-15 2001-01-31 Lumitech Uk Ltd Methods and kits for detecting kinase activity
GB0103622D0 (en) * 2001-02-14 2001-03-28 Univ Cambridge Tech Methods for detecting DNA polymerisation
JP2005509426A (ja) * 2001-11-14 2005-04-14 イギリス国 細胞内atpおよび/または遺伝子発現の測定方法
US7413874B2 (en) 2002-12-09 2008-08-19 University Of Miami Nucleic acid encoding fluorescent proteins from aquatic species
GB2400659B8 (en) 2003-04-17 2007-07-09 Cambrex Bio Science Nottingham Assay methods and materials
GB0416944D0 (en) 2004-07-29 2004-09-01 Lumora Ltd Method for determining the amount of template nucleic acid present in a sample
US7728118B2 (en) 2004-09-17 2010-06-01 Promega Corporation Synthetic nucleic acid molecule compositions and methods of preparation
JP5188771B2 (ja) 2007-09-26 2013-04-24 株式会社日立製作所 変異型ホタルルシフェラーゼ
EP2407551A3 (de) 2007-11-20 2012-04-18 Kikkoman Corporation Zusammensetzung zur Analyse von Nukleinsäure
CN102159948B (zh) 2008-07-22 2014-06-25 普罗美加公司 基于adp检测的发光磷酸转移酶或atp水解酶测定
JP2011120559A (ja) 2008-12-26 2011-06-23 Kikkoman Corp ホタルルシフェラーゼ、その遺伝子、およびホタルルシフェラーゼの製造法
PL2635583T3 (pl) 2010-11-02 2015-11-30 Promega Corp Pochodne koelenterazyny i metody ich wykorzystania
CA2817102C (en) 2010-11-02 2020-07-28 Promega Corporation Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
WO2014130760A1 (en) 2013-02-22 2014-08-28 Promega Corporation Stabilized formulation for luminescent detection of luciferase and nucleoside phosphates
JP6588917B2 (ja) 2014-01-29 2019-10-09 プロメガ コーポレイションPromega Corporation 生細胞への適用のためのプロ基質
US9790537B2 (en) 2014-01-29 2017-10-17 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
US9732373B2 (en) 2014-09-11 2017-08-15 Promega Corporation Luciferase sequences utilizing infrared-emitting substrates to produce enhanced luminescence
EP3204509B1 (de) 2014-10-08 2019-07-10 Promega Corporation Biolumineszierender test zum nachweis von succinat
DE102015215569A1 (de) 2015-08-14 2017-02-16 Robert Bosch Gmbh Verfahren zur Generierung eines Geheimnisses zwischen Teilnehmern eines Netzwerkes sowie dazu eingerichtete Teilnehmer des Netzwerks
EP4105336A4 (de) 2020-02-14 2024-04-10 Kikkoman Corp Flüssige zusammensetzung zur messung von atp sowie amp und/oder adp in proben

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5219737A (en) 1990-03-27 1993-06-15 Kikkoman Corporation Mutant luciferase of a firefly, mutant luciferase genes, recombinant dnas containing the genes and a method of producing mutant luciferase
US5229285A (en) * 1991-06-27 1993-07-20 Kikkoman Corporation Thermostable luciferase of firefly, thermostable luciferase gene of firefly, novel recombinant dna, and process for the preparation of thermostable luciferase of firefly
DE4123672A1 (de) 1991-07-17 1993-01-21 Basf Ag Siegelfaehige, peelbare kunststoffolie
ATE391769T1 (de) 1994-01-03 2008-04-15 Promega Corp Mutierte luziferasen
GB9501170D0 (en) * 1994-03-23 1995-03-08 Secr Defence Luciferases

Also Published As

Publication number Publication date
NO322134B1 (no) 2006-08-21
NO973349D0 (no) 1997-07-18
EP0804587B1 (de) 2004-08-18
AU4397396A (en) 1996-08-07
DE69633171T2 (de) 2005-08-18
NO973349L (no) 1997-09-19
AU707243B2 (en) 1999-07-08
US6171808B1 (en) 2001-01-09
IN186115B (de) 2001-06-23
JP4342608B2 (ja) 2009-10-14
JPH10512750A (ja) 1998-12-08
DK0804587T3 (da) 2004-10-11
CA2210354A1 (en) 1996-07-25
WO1996022376A1 (en) 1996-07-25
CA2210354C (en) 2008-01-08
EP0804587A1 (de) 1997-11-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: 3M INNOVATIVE PROPERTIES CO., ST. PAUL, MINN., US

8327 Change in the person/name/address of the patent owner

Owner name: PROMEGA CORP., MADISON, WIS., US