DE69631768D1 - Verwendung von l-carnitine und derivaten zur verminderung des ceramidspiegels und förderung der wirkung von antiretroviralen mitteln - Google Patents

Verwendung von l-carnitine und derivaten zur verminderung des ceramidspiegels und förderung der wirkung von antiretroviralen mitteln

Info

Publication number
DE69631768D1
DE69631768D1 DE69631768T DE69631768T DE69631768D1 DE 69631768 D1 DE69631768 D1 DE 69631768D1 DE 69631768 T DE69631768 T DE 69631768T DE 69631768 T DE69631768 T DE 69631768T DE 69631768 D1 DE69631768 D1 DE 69631768D1
Authority
DE
Germany
Prior art keywords
carnitines
derivatives
promote
reduce
effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69631768T
Other languages
English (en)
Other versions
DE69631768T2 (de
Inventor
Sonia Moretti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mendes SRL
Sigma Tau Industrie Farmaceutiche Riunite SpA
Original Assignee
Mendes SRL
Sigma Tau Industrie Farmaceutiche Riunite SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mendes SRL, Sigma Tau Industrie Farmaceutiche Riunite SpA filed Critical Mendes SRL
Application granted granted Critical
Publication of DE69631768D1 publication Critical patent/DE69631768D1/de
Publication of DE69631768T2 publication Critical patent/DE69631768T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/221—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having an amino group, e.g. acetylcholine, acetylcarnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Emergency Medicine (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE1996631768 1995-08-03 1996-07-19 Verwendung von l-carnitine und derivaten zur verminderung des ceramidspiegels und förderung der wirkung von antiretroviralen mitteln Expired - Lifetime DE69631768T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM950544 1995-08-03
IT95RM000544A IT1277897B1 (it) 1995-08-03 1995-08-03 Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre
PCT/IT1996/000146 WO1997005864A2 (en) 1995-08-03 1996-07-19 Use of l-carnitine and derivatives for reducing ceramide levels and potentiating antiretroviral drugs

Publications (2)

Publication Number Publication Date
DE69631768D1 true DE69631768D1 (de) 2004-04-08
DE69631768T2 DE69631768T2 (de) 2005-01-13

Family

ID=11403512

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1996631768 Expired - Lifetime DE69631768T2 (de) 1995-08-03 1996-07-19 Verwendung von l-carnitine und derivaten zur verminderung des ceramidspiegels und förderung der wirkung von antiretroviralen mitteln

Country Status (19)

Country Link
US (2) US6040346A (de)
EP (1) EP0839033B1 (de)
JP (1) JPH11510181A (de)
KR (1) KR100412532B1 (de)
CN (1) CN1161116C (de)
AR (1) AR004503A1 (de)
AT (1) ATE260654T1 (de)
AU (1) AU719906B2 (de)
BR (1) BR9609947A (de)
CA (1) CA2228266C (de)
DE (1) DE69631768T2 (de)
DK (1) DK0839033T3 (de)
ES (1) ES2216050T3 (de)
HK (1) HK1015273A1 (de)
IT (1) IT1277897B1 (de)
PT (1) PT839033E (de)
RU (2) RU2203047C2 (de)
TW (1) TW464493B (de)
WO (1) WO1997005864A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1277898B1 (it) 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
IT1277897B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre
US20010025027A1 (en) * 2000-03-07 2001-09-27 Sonis Stephen T. Inhibition of ceramide for the prevention and treatment of oral mucositis induced by antineoplastic drugs or radiation
IT1317938B1 (it) * 2000-11-17 2003-07-15 Sigma Tau Healthscience Spa Composizione per la prevenzione e/o il trattamento di alterazioni delmetabolismo lipidico, delle forme allergiche e per attivare le difese
EP2586438A1 (de) 2011-10-28 2013-05-01 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Verbindung zur Verwendung bei der Vorbeugung von kognitiven Mangelerscheinungen bei einem Neugeborenen von einer HIV-serumpositiven Mutter, die mit Azidothymidin
RU2559179C1 (ru) * 2014-03-24 2015-08-10 Илья Александрович Марков Фармацевтическая композиция для лечения тяжелых форм вирусных инфекций в виде таблеток
DE202017102551U1 (de) 2017-04-28 2017-06-01 E-Lead Electronic Co., Ltd. Verstellbares Allzeit-Head-Up-Displaysystem
EP4125858A1 (de) * 2020-04-28 2023-02-08 Lonza Consumer Health Inc. Ernährungszusammensetzung mit carnitin und verfahren zur behandlung oder prävention einer infektion bei einem säugetier

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU518617B2 (en) * 1977-04-29 1981-10-08 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Therapeutic application of acetyl-d, 1-carnitine
IE903343A1 (en) * 1989-09-18 1991-04-10 Smithkline Beecham Corp FORMULATION FOR SOLUBLE sT4 FOR TREATMENT OF HIV INFECTION
AU7148791A (en) * 1989-12-29 1991-07-24 Mcgaw, Inc. The use of arginine as an immunostimulator
IT1255039B (it) * 1992-03-11 1995-10-13 Sigma Tau Ind Farmaceuti Impiego di l-carnitina nel trattamento di pazienti hiv-sieropositivi presentanti deficit di carnitina.
IT1277898B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso di amminoacidi basici, di acil derivati di amminoacidi basici e di loro sali farmaceuticamente accettabili per la profilassi di malattie
IT1277897B1 (it) * 1995-08-03 1997-11-12 Mendes Srl Uso della l-carnitina,di suoi derivati e di loro sali farmaceuticamen- te accettabili in combinazione con farmaci antiretrovirali per ridurre
IT1283951B1 (it) * 1996-03-15 1998-05-07 Mendes Srl Uso della acetil l-carnitina o dei suoi sali farmacologicamente accettabili per il trattamento terapeutico o la profilassi di

Also Published As

Publication number Publication date
IT1277897B1 (it) 1997-11-12
ITRM950544A0 (it) 1995-08-03
AU719906B2 (en) 2000-05-18
CN1161116C (zh) 2004-08-11
WO1997005864A2 (en) 1997-02-20
AR004503A1 (es) 1998-12-16
CA2228266C (en) 2009-05-12
HK1015273A1 (en) 1999-10-15
KR19990036149A (ko) 1999-05-25
TW464493B (en) 2001-11-21
BR9609947A (pt) 1999-02-02
CN1193912A (zh) 1998-09-23
ES2216050T3 (es) 2004-10-16
JPH11510181A (ja) 1999-09-07
PT839033E (pt) 2004-07-30
ITRM950544A1 (it) 1997-02-03
CA2228266A1 (en) 1997-02-20
DE69631768T2 (de) 2005-01-13
RU2269340C2 (ru) 2006-02-10
EP0839033A2 (de) 1998-05-06
DK0839033T3 (da) 2004-06-21
US20040039054A1 (en) 2004-02-26
EP0839033B1 (de) 2004-03-03
MX9800915A (es) 1998-10-31
RU2203047C2 (ru) 2003-04-27
AU6469096A (en) 1997-03-05
KR100412532B1 (ko) 2004-06-10
ATE260654T1 (de) 2004-03-15
WO1997005864A3 (en) 1997-04-17
US6040346A (en) 2000-03-21

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