DE69618765T2 - Verwendung von kompocedinderivaten zur inhibierung der bildung oder sekretion von beta-amyloid-protein - Google Patents

Verwendung von kompocedinderivaten zur inhibierung der bildung oder sekretion von beta-amyloid-protein

Info

Publication number
DE69618765T2
DE69618765T2 DE69618765T DE69618765T DE69618765T2 DE 69618765 T2 DE69618765 T2 DE 69618765T2 DE 69618765 T DE69618765 T DE 69618765T DE 69618765 T DE69618765 T DE 69618765T DE 69618765 T2 DE69618765 T2 DE 69618765T2
Authority
DE
Germany
Prior art keywords
pct
optionally substituted
secretion
date
compocedine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69618765T
Other languages
English (en)
Other versions
DE69618765D1 (de
Inventor
Mitsuru Kakihana
Takuo Kosaka
Akinobu Nagaoka
Giichi Goto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69618765D1 publication Critical patent/DE69618765D1/de
Publication of DE69618765T2 publication Critical patent/DE69618765T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69618765T 1995-02-15 1996-02-08 Verwendung von kompocedinderivaten zur inhibierung der bildung oder sekretion von beta-amyloid-protein Expired - Fee Related DE69618765T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2668795 1995-02-15
PCT/JP1996/000265 WO1996025161A1 (en) 1995-02-15 1996-02-08 Use of vinpocetine derivatives for inhibiting production or secretion of amyloid beta protein

Publications (2)

Publication Number Publication Date
DE69618765D1 DE69618765D1 (de) 2002-03-14
DE69618765T2 true DE69618765T2 (de) 2002-10-17

Family

ID=12200316

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69618765T Expired - Fee Related DE69618765T2 (de) 1995-02-15 1996-02-08 Verwendung von kompocedinderivaten zur inhibierung der bildung oder sekretion von beta-amyloid-protein

Country Status (11)

Country Link
US (1) US5965568A (de)
EP (1) EP0813411B1 (de)
AT (1) ATE212227T1 (de)
AU (1) AU4632996A (de)
CA (1) CA2213094A1 (de)
DE (1) DE69618765T2 (de)
DK (1) DK0813411T3 (de)
ES (1) ES2171646T3 (de)
HU (1) HUP9801155A3 (de)
PT (1) PT813411E (de)
WO (1) WO1996025161A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000024392A1 (fr) * 1998-10-26 2000-05-04 Sumitomo Pharmaceuticals Company, Limited Inhibiteur de la formation de beta-amyloide
ATE526020T1 (de) * 2000-08-10 2011-10-15 Cold Spring Harbor Lab Gesteigertes kognitives training
US8153646B2 (en) * 2000-08-10 2012-04-10 Dart Neuroscience (Cayman) Ltd. Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation
EP1565202A2 (de) * 2002-11-22 2005-08-24 Novartis AG Zusammensetzungen zur behandlung von alzheimer-krankheit
CN100500146C (zh) * 2003-10-28 2009-06-17 墨西哥国立自治大学 长春西汀及其衍生物在癫痫及其并发症的治疗和预防中的应用
GB0329498D0 (en) 2003-12-19 2004-01-28 Novartis Ag Organic compounds
WO2005087212A1 (en) * 2004-03-12 2005-09-22 Egis Gyógyszergyár Nyrt. Combined pharmaceutical composition for the inhibition of the decline of cognitive functions
JP5160764B2 (ja) * 2006-10-13 2013-03-13 全薬工業株式会社 特定の構造の複素環化合物を含む抗鬱剤、脳保護剤、アミロイドβ沈着抑制剤または老化抑制剤
KR101095026B1 (ko) * 2009-01-23 2011-12-20 한국과학기술연구원 비스(스티릴)피리미딘 및 비스(스티릴)벤젠 유도체, 이의 약학적으로 허용 가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 베타아밀로이드 집적 관련 질환의 예방 또는 치료용 약학적 조성물
WO2010103539A2 (en) 2009-03-09 2010-09-16 Dinesh Shantilal Patel Sustained release oral formulation of vinpocetine
CN102875547B (zh) * 2011-07-15 2015-05-27 海南灵康制药有限公司 一种长春西汀化合物及其制法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035370A (en) * 1971-11-03 1977-07-12 Richter Gedeon Vegyeszeti Gyar Rt. Alkaloid esters
HU181941B (en) * 1979-11-23 1983-11-28 Richter Gedeon Vegyeszet Process for producing apovincaminic acid ester derivatives
HU201674B (en) * 1987-08-26 1990-12-28 Richter Gedeon Vegyeszet Process for producing pharmaceutical composition suitable for curing autoimmune-type leukoencephalomyelitic diseases e.g. sclerosis multiplex
JPH02167279A (ja) * 1988-09-30 1990-06-27 Taisho Pharmaceut Co Ltd アポビンカミン酸誘導体
JPH02152979A (ja) * 1988-12-06 1990-06-12 Taisho Pharmaceut Co Ltd アポビンカミン酸誘導体
JPH02204488A (ja) * 1989-02-03 1990-08-14 Taisho Pharmaceut Co Ltd エブルナメニン誘導体
JP3053913B2 (ja) * 1991-07-15 2000-06-19 帝三製薬株式会社 ビンポセチン類含有貼付剤
US5296478A (en) * 1992-10-07 1994-03-22 The Dupont Merck Pharmaceutical Co. 1-substituted oxindoles as cognition enhancers
EP1308461A3 (de) * 1993-01-25 2004-02-11 Takeda Chemical Industries, Ltd. Antikörper gegen Beta-Amyloiden oder deren Abarten, und deren Verwendungen

Also Published As

Publication number Publication date
DK0813411T3 (da) 2002-05-13
EP0813411B1 (de) 2002-01-23
ES2171646T3 (es) 2002-09-16
AU4632996A (en) 1996-09-04
CA2213094A1 (en) 1996-08-22
HUP9801155A2 (hu) 1998-09-28
DE69618765D1 (de) 2002-03-14
PT813411E (pt) 2002-07-31
WO1996025161A1 (en) 1996-08-22
US5965568A (en) 1999-10-12
EP0813411A1 (de) 1997-12-29
ATE212227T1 (de) 2002-02-15
HUP9801155A3 (en) 1999-03-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: RICHTER GEDEON VEGYESZETI GYAR R.T., BUDAPEST, HU

8339 Ceased/non-payment of the annual fee