DE69614450T2 - In-situ Lyophilisierung eines Vaginalzäpfchens in einem Einzeldosisapplikator und das enstandene Produkt - Google Patents

In-situ Lyophilisierung eines Vaginalzäpfchens in einem Einzeldosisapplikator und das enstandene Produkt

Info

Publication number
DE69614450T2
DE69614450T2 DE69614450T DE69614450T DE69614450T2 DE 69614450 T2 DE69614450 T2 DE 69614450T2 DE 69614450 T DE69614450 T DE 69614450T DE 69614450 T DE69614450 T DE 69614450T DE 69614450 T2 DE69614450 T2 DE 69614450T2
Authority
DE
Germany
Prior art keywords
single dose
resulting product
vaginal suppository
dose applicator
situ
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69614450T
Other languages
English (en)
Other versions
DE69614450D1 (de
Inventor
Barbara Brummer
Paul Swick
Martin Link
William Hart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
Ortho Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp
Application granted granted Critical
Publication of DE69614450D1 publication Critical patent/DE69614450D1/de
Publication of DE69614450T2 publication Critical patent/DE69614450T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/08Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of suppositories or sticks

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
DE69614450T 1995-06-08 1996-06-07 In-situ Lyophilisierung eines Vaginalzäpfchens in einem Einzeldosisapplikator und das enstandene Produkt Expired - Lifetime DE69614450T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/495,738 US5656283A (en) 1995-06-08 1995-06-08 In-situ lyophilization of vaginal suppository in unit dose applicator and resultant product

Publications (2)

Publication Number Publication Date
DE69614450D1 DE69614450D1 (de) 2001-09-20
DE69614450T2 true DE69614450T2 (de) 2002-05-29

Family

ID=23969826

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69614450T Expired - Lifetime DE69614450T2 (de) 1995-06-08 1996-06-07 In-situ Lyophilisierung eines Vaginalzäpfchens in einem Einzeldosisapplikator und das enstandene Produkt

Country Status (16)

Country Link
US (1) US5656283A (de)
EP (1) EP0747045B1 (de)
JP (1) JP3810865B2 (de)
AT (1) ATE204161T1 (de)
AU (2) AU714230B2 (de)
BR (1) BR9602703A (de)
CA (1) CA2178566C (de)
DE (1) DE69614450T2 (de)
DK (1) DK0747045T3 (de)
ES (1) ES2161330T3 (de)
HK (1) HK1003419A1 (de)
MX (1) MX9602255A (de)
NO (1) NO313575B1 (de)
NZ (1) NZ286745A (de)
PT (1) PT747045E (de)
WO (1) WO1996041615A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102019109956B4 (de) 2018-04-19 2023-01-05 Philip Großkord Vorrichtung zur Dosierung von flüssigen Stoffen in Körperöffnungen

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EA000818B1 (ru) 1995-12-27 2000-04-24 Жансен Фармасетика Н.В. Биоадгезивная твердая дозированная лекарственная форма
US5997572A (en) 1996-03-29 1999-12-07 Augustine Medical, Inc. Inlet port plug for inflatable thermal blankets
US20020026157A1 (en) * 1998-12-07 2002-02-28 Fournier Arthur M. Feminine, self-administrable sampling and topical therapy device and method
BR0007360A (pt) * 1999-12-23 2001-08-14 Johnson & Johnson Composição de liberação controlada
US6923789B2 (en) * 2002-02-22 2005-08-02 Playtex Products, Inc. Multiple-component tampon applicator
US7717873B2 (en) * 2002-06-14 2010-05-18 Mcneil-Ppc, Inc. Applicator device for suppositories and the like
US7198612B2 (en) * 2002-06-14 2007-04-03 Mcneil-Ppc, Inc. Applicator device for suppositories and the like
US7104968B2 (en) * 2002-06-14 2006-09-12 Mcneil-Ppc, Inc. Applicator device for suppositories and the like
US7217252B2 (en) * 2002-06-14 2007-05-15 Mcneil-Ppc, Inc. Applicator device for medicated materials
DE10246003B4 (de) * 2002-10-02 2005-06-30 Anliker, Markus, Dr.med. Suppositorienverpackung
US7456207B2 (en) * 2003-09-25 2008-11-25 Teva Pharmaceuticals Usa, Inc. Vaginal pharmaceutical compositions and methods for preparing them
US7993667B2 (en) 2005-03-25 2011-08-09 Kimberly-Clark Worldwide, Inc. Methods of manufacturing a medicated tampon assembly
US7919453B2 (en) 2005-03-25 2011-04-05 Kimberly-Clark Worldwide, Inc. Dosage cap assembly for an applicator
US7744556B2 (en) * 2005-03-25 2010-06-29 Kimberly-Clark Worldwide, Inc. Delivery tube assembly for an applicator
US7708726B2 (en) 2005-04-28 2010-05-04 Kimberly-Clark Worldwide, Inc. Dosage form cap for an applicator
WO2007062668A1 (en) * 2005-12-04 2007-06-07 Kariem Ezzat Mahmoud The intra-nasal suppository
US9662481B2 (en) 2008-10-07 2017-05-30 Cristcot Llc Method and apparatus for inserting a rectal suppository
US8192393B2 (en) 2008-10-07 2012-06-05 Christcot Medical Company Method and apparatus for inserting a rectal suppository
AU2011209940B2 (en) 2010-02-01 2015-08-20 Mikrobex Inc. Bacteriotherapy for clostridium difficile colitis
ITUD20100112A1 (it) * 2010-06-09 2011-12-10 Farma Derma S R L Preparazione per uso vaginale e rettale e relativo procedimento di produzione
JP5868674B2 (ja) * 2011-11-29 2016-02-24 株式会社吉野工業所 座薬挿入器具
EP3248499A2 (de) * 2012-10-19 2017-11-29 Cristcot LLC Lippenstift und verfahren zur herstellung eines lippenstiftes
KR102093537B1 (ko) 2013-06-05 2020-04-23 리바이오틱스, 인코퍼레이티드 미생물상 복원 요법(mrt), 조성물 및 제조방법
US9511100B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US10383901B2 (en) 2013-06-05 2019-08-20 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9782445B2 (en) 2013-06-05 2017-10-10 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US10799539B2 (en) 2015-06-09 2020-10-13 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
KR102066242B1 (ko) 2015-06-09 2020-01-14 리바이오틱스, 인코퍼레이티드 미생물상 복원 치료(mrt) 조성물 및 제조 방법
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
JP7061967B2 (ja) 2016-05-12 2022-05-02 クリストコット エルエルシー 使い捨て座薬挿入装置及び方法
CN110975121A (zh) * 2019-12-21 2020-04-10 李天艳 一种外科护理药栓给药固定装置

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US3234091A (en) * 1955-07-08 1966-02-08 Ciba Geigy Corp Shaped medicaments and process for their manufacture
DE1491876A1 (de) * 1966-10-14 1970-04-16 Robert Fuchslocher Medizinisches Geraet zur rektalen oder sonstigen Einfuehrung von Medikamenten in Koerperoeffnungen
US3667465A (en) * 1969-12-08 1972-06-06 Kimberly Clark Co Applicator tubes for suppositories and the like
US3812250A (en) * 1971-03-04 1974-05-21 E Aubert Antifungal suppository and method of treating fungus infestations
US3749093A (en) * 1971-08-10 1973-07-31 S Bloom Insertable device package
US3831605A (en) * 1973-01-26 1974-08-27 E Fournier Multipurpose applicators
US3830236A (en) * 1973-02-28 1974-08-20 Kimberly Clark Co Applicator tube for inserting hygienic media
US3884233A (en) * 1973-09-04 1975-05-20 Betty Louise Summey Tampon and suppository combination
GB1593261A (en) * 1976-07-23 1981-07-15 Inveresk Res Int Controlled release suppository
US4406883A (en) * 1976-07-23 1983-09-27 Merrell Dow Pharmaceuticals Inc. Controlled release suppositories consisting essentially of a linear polymer particularly, polyvinyl pyrrolidones
US4361150A (en) * 1980-04-07 1982-11-30 Voss Joseph A Extruded plastic hygienic applicator
US4292972A (en) * 1980-07-09 1981-10-06 E. R. Squibb & Sons, Inc. Lyophilized hydrocolloio foam
USD289691S (en) 1984-03-30 1987-05-05 Novo Industri A/S Applicator for inserting a suppositorium or the like
FR2657258A1 (fr) * 1990-01-19 1991-07-26 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des particules sous forme de perles ainsi que sa preparation.
US5330427A (en) * 1991-07-02 1994-07-19 Ortho Pharmaceutical Corporation Prefilled suppository applicator
US5213566A (en) * 1991-07-02 1993-05-25 Ortho Pharmaceutical Corporation Prefilled suppository applicator
AU673812B2 (en) * 1992-01-13 1996-11-28 Tambrands, Inc. Tampon applicator
US5354558A (en) * 1992-09-10 1994-10-11 Mcneil-Pcc, Inc. Bioerodible contraceptive suppository
US5458884A (en) * 1992-09-10 1995-10-17 Britton; Peter Bioerodible device for administering active ingredients

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102019109956B4 (de) 2018-04-19 2023-01-05 Philip Großkord Vorrichtung zur Dosierung von flüssigen Stoffen in Körperöffnungen

Also Published As

Publication number Publication date
EP0747045B1 (de) 2001-08-16
AU714230B2 (en) 1999-12-23
MX9602255A (es) 1997-04-30
DK0747045T3 (da) 2001-10-08
AU5582696A (en) 1996-12-19
AU6334596A (en) 1997-01-09
EP0747045A2 (de) 1996-12-11
JPH09103467A (ja) 1997-04-22
WO1996041615A2 (en) 1996-12-27
NZ286745A (en) 1997-06-24
US5656283A (en) 1997-08-12
ES2161330T3 (es) 2001-12-01
NO313575B1 (no) 2002-10-28
JP3810865B2 (ja) 2006-08-16
BR9602703A (pt) 1998-04-22
EP0747045A3 (de) 1997-04-16
HK1003419A1 (en) 1998-10-30
ATE204161T1 (de) 2001-09-15
CA2178566C (en) 2007-05-08
PT747045E (pt) 2001-11-30
CA2178566A1 (en) 1996-12-09
NO962423D0 (no) 1996-06-07
DE69614450D1 (de) 2001-09-20
NO962423L (no) 1996-12-09

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN