DE69602248T2 - 4a-aryldecahydroisochinolin-verbindungen und ihre medizinische verwendungen - Google Patents
4a-aryldecahydroisochinolin-verbindungen und ihre medizinische verwendungenInfo
- Publication number
- DE69602248T2 DE69602248T2 DE69602248T DE69602248T DE69602248T2 DE 69602248 T2 DE69602248 T2 DE 69602248T2 DE 69602248 T DE69602248 T DE 69602248T DE 69602248 T DE69602248 T DE 69602248T DE 69602248 T2 DE69602248 T2 DE 69602248T2
- Authority
- DE
- Germany
- Prior art keywords
- aryldecahydroisochinoline
- compounds
- medical use
- medical
- aryldecahydroisochinoline compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP18381195 | 1995-07-20 | ||
| PCT/JP1996/002030 WO1997003968A1 (fr) | 1995-07-20 | 1996-07-19 | COMPOSES DE 4a-ARYLDECAHYDROISOQUINOLEINE ET LEURS UTILISATIONS MEDICALES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69602248T2 true DE69602248T2 (de) | 1999-09-23 |
| DE69602248T4 DE69602248T4 (de) | 2000-10-26 |
Family
ID=16142292
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69602248T Expired - Lifetime DE69602248T4 (de) | 1995-07-20 | 1996-07-19 | 4a-aryldecahydroisochinolin-verbindungen und ihre medizinische verwendungen |
| DE69602248A Expired - Fee Related DE69602248D1 (de) | 1995-07-20 | 1996-07-19 | 4a-aryldecahydroisochinolin-verbindungen und ihre medizinische verwendungen |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69602248A Expired - Fee Related DE69602248D1 (de) | 1995-07-20 | 1996-07-19 | 4a-aryldecahydroisochinolin-verbindungen und ihre medizinische verwendungen |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5776945A (de) |
| EP (1) | EP0787721B1 (de) |
| JP (1) | JP3858273B2 (de) |
| KR (1) | KR970706258A (de) |
| CN (1) | CN1163487C (de) |
| AU (1) | AU6470996A (de) |
| CA (1) | CA2200324C (de) |
| DE (2) | DE69602248T4 (de) |
| ES (1) | ES2133975T3 (de) |
| TW (1) | TW430657B (de) |
| WO (1) | WO1997003968A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1219624B1 (de) * | 1999-08-24 | 2008-07-09 | Toray Industries, Inc. | Heilmittel für neuropathischen schmerz und versuchstier-modelle des neuropathischen schmerzes |
| ME02733B (de) * | 2011-10-18 | 2017-10-20 | Astellas Pharma Inc | Bicyclische heterocyclische verbindung |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4301290A (en) * | 1975-12-16 | 1981-11-17 | Sandoz Ltd. | Organic compounds |
| DE2655150A1 (de) * | 1975-12-16 | 1977-06-23 | Sandoz Ag | Neue organische verbindungen, ihre herstellung und verwendung |
| AT371445B (de) * | 1977-05-24 | 1983-06-27 | Sandoz Ag | Verfahren zur herstellung von neuen cis-4a-phenyl-isochinolinderivaten und ihren saeureadditionssalzen |
| DE2907461A1 (de) * | 1978-03-10 | 1979-09-20 | Sandoz Ag | Isochinolinderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen |
| US4189583A (en) * | 1978-04-26 | 1980-02-19 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Synthesis of 4A-aryl-decahydroisoquinolines |
| JPH04297458A (ja) * | 1991-03-27 | 1992-10-21 | Toray Ind Inc | イソキノリン誘導体およびその製造方法 |
| CA2224047A1 (en) * | 1990-06-05 | 1991-12-06 | Toray Industries, Inc. | Indole derivatives |
| JP2985322B2 (ja) * | 1991-03-01 | 1999-11-29 | 東レ株式会社 | イソキノリン誘導体およびその医薬用途 |
| JPH05155857A (ja) * | 1991-12-03 | 1993-06-22 | Toray Ind Inc | ４ａ−アリールデカヒドロイソキノリン誘導体および鎮痛剤 |
-
1996
- 1996-07-19 KR KR1019970701817A patent/KR970706258A/ko not_active Application Discontinuation
- 1996-07-19 WO PCT/JP1996/002030 patent/WO1997003968A1/ja not_active Application Discontinuation
- 1996-07-19 DE DE69602248T patent/DE69602248T4/de not_active Expired - Lifetime
- 1996-07-19 DE DE69602248A patent/DE69602248D1/de not_active Expired - Fee Related
- 1996-07-19 JP JP50654497A patent/JP3858273B2/ja not_active Expired - Fee Related
- 1996-07-19 CA CA002200324A patent/CA2200324C/en not_active Expired - Fee Related
- 1996-07-19 EP EP96924167A patent/EP0787721B1/de not_active Expired - Lifetime
- 1996-07-19 AU AU64709/96A patent/AU6470996A/en not_active Abandoned
- 1996-07-19 ES ES96924167T patent/ES2133975T3/es not_active Expired - Lifetime
- 1996-07-19 US US08/809,226 patent/US5776945A/en not_active Expired - Fee Related
- 1996-07-19 CN CNB961910666A patent/CN1163487C/zh not_active Expired - Fee Related
- 1996-09-05 TW TW085110865A patent/TW430657B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| TW430657B (en) | 2001-04-21 |
| CN1163487C (zh) | 2004-08-25 |
| DE69602248T4 (de) | 2000-10-26 |
| EP0787721A1 (de) | 1997-08-06 |
| CA2200324C (en) | 2008-07-08 |
| CN1165513A (zh) | 1997-11-19 |
| CA2200324A1 (en) | 1997-02-06 |
| AU6470996A (en) | 1997-02-18 |
| JP3858273B2 (ja) | 2006-12-13 |
| WO1997003968A1 (fr) | 1997-02-06 |
| KR970706258A (ko) | 1997-11-03 |
| EP0787721B1 (de) | 1999-04-28 |
| US5776945A (en) | 1998-07-07 |
| EP0787721A4 (de) | 1997-09-17 |
| ES2133975T3 (es) | 1999-09-16 |
| DE69602248D1 (de) | 1999-06-02 |
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