DE69534151D1 - Gefriergetrocknete Blutzellen, Stammzellen und Plättchen und Verfahren zu deren Herstellung - Google Patents
Gefriergetrocknete Blutzellen, Stammzellen und Plättchen und Verfahren zu deren HerstellungInfo
- Publication number
- DE69534151D1 DE69534151D1 DE69534151T DE69534151T DE69534151D1 DE 69534151 D1 DE69534151 D1 DE 69534151D1 DE 69534151 T DE69534151 T DE 69534151T DE 69534151 T DE69534151 T DE 69534151T DE 69534151 D1 DE69534151 D1 DE 69534151D1
- Authority
- DE
- Germany
- Prior art keywords
- platelets
- freeze
- preparation
- dried blood
- stem cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 210000000601 blood cell Anatomy 0.000 title 1
- 210000001772 blood platelet Anatomy 0.000 title 1
- 210000000130 stem cell Anatomy 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/16—Blood plasma; Blood serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4655194 | 1994-02-22 | ||
JP4653194 | 1994-02-22 | ||
JP4655194 | 1994-02-22 | ||
JP4653194 | 1994-02-22 | ||
JP21668394 | 1994-08-19 | ||
JP21668394 | 1994-08-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69534151D1 true DE69534151D1 (de) | 2005-05-25 |
DE69534151T2 DE69534151T2 (de) | 2006-01-12 |
Family
ID=27292632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69534151T Expired - Fee Related DE69534151T2 (de) | 1994-02-22 | 1995-02-21 | Gefriergetrocknete Blutzellen, Stammzellen und Plättchen und Verfahren zu deren Herstellung |
Country Status (3)
Country | Link |
---|---|
US (1) | US5656498A (de) |
EP (1) | EP0668013B1 (de) |
DE (1) | DE69534151T2 (de) |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0904844A4 (de) * | 1996-06-10 | 2005-08-31 | Nippon Telegraph & Telephone | Zweistoffdüse und vorrichtung mit dieser düse zum einfrieren und trocknen einer in einem behälter enthaltenen flüssigkeit |
DE69810755T2 (de) * | 1997-02-07 | 2003-08-07 | Elan Drug Delivery Ltd | Verfahren und zusammensetzungen zur herstellung getrockneter, lagerungsstabiler blutplättchen |
GB2329124B (en) * | 1997-09-12 | 2002-05-08 | Hiran Asoka Malinga Ratwatte | Method of forming dose units of active agents |
GB2343679A (en) * | 1998-11-16 | 2000-05-17 | Alison Miriam Davies | Autologous transplantation and method for making cells dormant |
EP1255439A4 (de) * | 2000-02-10 | 2007-01-03 | Univ California | Therapeutische plättchen und verfahren |
US6770478B2 (en) | 2000-02-10 | 2004-08-03 | The Regents Of The University Of California | Erythrocytic cells and method for preserving cells |
WO2001088099A1 (en) * | 2000-05-16 | 2001-11-22 | Alison Davies | Cells, culture methods and their uses |
US7648699B2 (en) | 2000-06-02 | 2010-01-19 | Caridianbct Biotechnologies, Llc | Preventing transfusion related complications in a recipient of a blood transfusion |
TW590780B (en) | 2000-06-02 | 2004-06-11 | Gambro Inc | Additive solutions containing riboflavin |
US7985588B2 (en) | 2000-06-02 | 2011-07-26 | Caridianbct Biotechnologies, Llc | Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light |
KR20010008306A (ko) * | 2000-11-22 | 2001-02-05 | 김진경 | 저온처리 후 조직 배양 방법 |
US6548241B1 (en) | 2000-11-28 | 2003-04-15 | Gambro, Inc. | Storage solution containing photosensitizer for inactivation of biological contaminants |
GB0230152D0 (en) * | 2002-12-24 | 2003-02-05 | Sinvent As | Product |
WO2004096113A2 (en) | 2003-04-28 | 2004-11-11 | Medical Instill Technologies, Inc. | Container with valve assembly for filling and dispensing substances, and apparatus and method for filling |
JP5183068B2 (ja) * | 2003-12-22 | 2013-04-17 | フィンレイ,ウォーレン,エイチ | 大気噴出凍結乾燥法による粉末形成 |
EP1711214A1 (de) | 2004-02-02 | 2006-10-18 | Interface Multigrad Technology (IMT) Ltd. | Vorrichtung zum gerichteten kühlen von biomasse |
US7935478B2 (en) | 2004-02-02 | 2011-05-03 | Core Dynamics Limited | Biological material and methods and solutions for preservation thereof |
ATE460947T1 (de) | 2004-06-07 | 2010-04-15 | Core Dynamics Ltd | Verfahren zur sterilisation von biologischen präparaten |
US8486617B2 (en) | 2004-08-12 | 2013-07-16 | Cellphirc, Inc | Methods for preparing freeze-dried platelets, compositions comprising freeze-dried platelets, and methods of use |
US8037696B2 (en) | 2004-08-12 | 2011-10-18 | Core Dynamics Limited | Method and apparatus for freezing or thawing of a biological material |
US8198085B2 (en) | 2005-08-03 | 2012-06-12 | Core Dynamics Limited | Somatic cells for use in cell therapy |
MX2008002023A (es) * | 2005-08-11 | 2008-04-08 | Harvard College | Metodos y composiciones para secar formas celulares. |
US20070122344A1 (en) | 2005-09-02 | 2007-05-31 | University Of Rochester Medical Center Office Of Technology Transfer | Intraoperative determination of nerve location |
EP1929289B1 (de) | 2005-09-26 | 2018-02-21 | Lifecell Corporation | Trockene thrombozyten-zusammensetzung |
US7966746B2 (en) * | 2006-04-24 | 2011-06-28 | Medical Instill Technologies, LLC | Needle penetrable and laser resealable lyophilization method |
US20080161744A1 (en) | 2006-09-07 | 2008-07-03 | University Of Rochester Medical Center | Pre-And Intra-Operative Localization of Penile Sentinel Nodes |
EP2155860B1 (de) | 2007-05-03 | 2014-08-27 | The Brigham and Women's Hospital, Inc. | Multipotente stammzellen und ihre verwendung |
US8406860B2 (en) | 2008-01-25 | 2013-03-26 | Novadaq Technologies Inc. | Method for evaluating blush in myocardial tissue |
US10219742B2 (en) | 2008-04-14 | 2019-03-05 | Novadaq Technologies ULC | Locating and analyzing perforator flaps for plastic and reconstructive surgery |
ES2671710T3 (es) | 2008-05-02 | 2018-06-08 | Novadaq Technologies ULC | Métodos para la producción y uso de eritrocitos cargados con sustancias para la observación y el tratamiento de la hemodinámica microvascular |
US10492671B2 (en) | 2009-05-08 | 2019-12-03 | Novadaq Technologies ULC | Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest |
WO2012098358A1 (en) * | 2011-01-20 | 2012-07-26 | Biopharma Technology Ltd | Freeze drying method |
GB201101002D0 (en) * | 2011-01-20 | 2011-03-09 | Biopharma Technology Ltd | Freeze drying method |
WO2012154301A1 (en) | 2011-03-18 | 2012-11-15 | Tornier, Inc. | Allogeneic microvascular tissue for soft tissue treatments |
WO2013084190A1 (en) | 2011-12-08 | 2013-06-13 | Yeda Research And Development Co. Ltd. | Mammalian fetal pulmonary cells and therapeutic use of same |
WO2013116307A1 (en) | 2012-01-30 | 2013-08-08 | Mount Sinai School Of Medicine | Method for programming differentiated cells into hematopoietic stem cells |
JP2015510401A (ja) | 2012-02-22 | 2015-04-09 | ブレインステム バイオテック リミテッド | ヒト疾患のインビトロモデル化および細胞に基づく治療のための間葉系幹細胞ならびにそのバンク |
EP2863801B8 (de) | 2012-06-21 | 2024-06-12 | Stryker Corporation | Quantifizierung und analyse von angiografie und perfusionen |
EP2880151B1 (de) | 2012-08-06 | 2020-06-03 | Brainstorm Cell Therapeutics Ltd. | Verfahren zur erzeugung mesenchymaler stammzellen mit ausscheidung neurotropher faktoren |
US10596202B2 (en) | 2012-09-19 | 2020-03-24 | Microvascular Tissues, Inc. | Compositions and methods for treating and preventing tissue injury and disease |
US9872937B2 (en) | 2012-09-19 | 2018-01-23 | Microvascular Tissues, Inc. | Compositions and methods for treating and preventing tissue injury and disease |
US11819522B2 (en) | 2012-09-19 | 2023-11-21 | Microvascular Tissues, Inc. | Compositions and methods for treating and preventing tissue injury and disease |
EP2898064B1 (de) | 2012-09-19 | 2018-11-14 | Microvascular Tissues, Inc. | Zusammensetzungen zur behandlung und prävention von gewebeverletzungen und -krankheiten |
WO2014118785A1 (en) | 2013-02-04 | 2014-08-07 | Ramot At Tel-Aviv University Ltd. | Generation of cytotoxic tumor specific cell lines and uses thereof |
EP3769618A1 (de) | 2014-06-09 | 2021-01-27 | Terumo BCT, Inc. | Behälter zur lyophilisierung |
KR102068776B1 (ko) | 2014-09-29 | 2020-01-21 | 노바다크 테크놀러지즈 유엘씨 | 자가형광이 존재하는 생물학적 물질에서 타겟 형광체의 이미징 |
US10631746B2 (en) | 2014-10-09 | 2020-04-28 | Novadaq Technologies ULC | Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography |
WO2016111899A1 (en) | 2015-01-05 | 2016-07-14 | Petrucci Gary M | Methods and materials for treating lung disorders |
US10897891B2 (en) | 2015-04-10 | 2021-01-26 | Board Of Regents, The University Of Texas System | Compositions and methods for prolonged cell storage |
ES2917884T3 (es) | 2015-06-18 | 2022-07-12 | Yeda Res & Dev | Protocolos de acondicionamiento y uso de los mismos para la regeneración de tejidos |
PL3322424T3 (pl) | 2015-07-16 | 2024-03-04 | Yeda Research And Development Co., Ltd. | Zastosowanie centralnych limfocytów t pamięci przeciwko stronie trzeciej |
US11261433B2 (en) | 2016-01-31 | 2022-03-01 | Hadasit Medical Research Services And Development Ltd. | Autosomal-identical pluripotent stem cell populations having non-identical sex chromosomal composition and uses thereof |
US10993969B2 (en) | 2016-02-05 | 2021-05-04 | Gary M. Petrucci | Methods and materials for treating nerve injuries and neurological disorders |
WO2017203520A1 (en) | 2016-05-22 | 2017-11-30 | Yeda Research And Development Co. Ltd. | Methods of using pulmonary cells for transplantation and induction of tolerance |
EP4242743A3 (de) | 2017-02-10 | 2023-10-18 | Stryker European Operations Limited | Handhaltbare offenfeld-fluoreszenzbildgebungssysteme und verfahren |
US10478531B2 (en) | 2017-06-22 | 2019-11-19 | Gary M. Petrucci | Methods and materials for treating blood vessels |
US10251917B1 (en) | 2017-09-19 | 2019-04-09 | Gary M. Petrucci | Methods and materials for treating tumors |
US10793327B2 (en) | 2017-10-09 | 2020-10-06 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
EP3886879A4 (de) | 2018-11-30 | 2022-12-07 | Cellphire Inc. | Thrombozyten als freisetzungsmittel |
WO2020113101A1 (en) | 2018-11-30 | 2020-06-04 | Cellphire, Inc. | Platelets loaded with anti-cancer agents |
EP3938742A1 (de) | 2019-03-14 | 2022-01-19 | Terumo BCT Biotechnologies, LLC | Mehrteiliger lyophilisierungsbehälter und verwendungsverfahren |
CA3138529A1 (en) | 2019-05-03 | 2020-11-12 | Cellphire, Inc. | Materials and methods for producing blood products |
US20210308185A1 (en) | 2020-02-04 | 2021-10-07 | Cellphire, Inc. | Methods of treating acquired hemophilia with anti-fibrinolytic loaded platelets |
CA3150936A1 (en) | 2019-08-16 | 2021-02-25 | Cellphire, Inc. | Thrombosomes as an antiplatelet agent reversal agent |
WO2021046409A1 (en) * | 2019-09-05 | 2021-03-11 | Cellphire, Inc. | Materials and methods for blood plasma preparations |
WO2022118220A1 (en) | 2020-12-02 | 2022-06-09 | Breathe Restore, Inc. | Compositions, devices, and methods for treating respiratory disorders |
US11672929B2 (en) | 2020-12-02 | 2023-06-13 | Breathe Restore, Inc. | Product delivery devices and methods |
CA3240113A1 (en) | 2021-12-08 | 2023-06-15 | Yeda Research And Development Co. Ltd. | Multipotent lung progenitor cells for lung regeneration |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3228838A (en) * | 1959-04-23 | 1966-01-11 | Union Carbide Corp | Preservation of biological substances |
US3928566A (en) * | 1970-08-14 | 1975-12-23 | Du Pont | Lyophilized biological products |
FR2154452B1 (de) * | 1971-09-03 | 1976-03-05 | Du Pont | |
US4329787A (en) * | 1980-01-04 | 1982-05-18 | Newton William A | Droplet exploding and freezing apparatus and method |
JPS59139959A (ja) * | 1984-01-25 | 1984-08-11 | Kimitoshi Mato | 高速渦流気体による超微粒子発生用ノズル |
JPS60251948A (ja) * | 1984-05-26 | 1985-12-12 | Kimitoshi Mato | 高速渦流気体による超微粒子発生用ノズル |
JPS6245365A (ja) * | 1985-08-22 | 1987-02-27 | Kimitoshi Mato | 二流体ノズル |
JPS62201665A (ja) * | 1986-03-01 | 1987-09-05 | Kimitoshi Mato | 二流体ノズル |
US5171661A (en) * | 1988-05-18 | 1992-12-15 | Cryopharm Corporation | Medium for lyophilization of erythrocytes |
US4874690A (en) * | 1988-08-26 | 1989-10-17 | Cryopharm Corporation | Lyophilization of red blood cells |
AU650045B2 (en) * | 1990-09-12 | 1994-06-09 | Lifecell Corporation | Method and apparatus for cryopreparation dry stabilization and rehydration of biological suspensions |
AU1415992A (en) * | 1991-02-15 | 1992-09-15 | Cryopharm Corporation | Method of lyophilization and reconstitution of mixtures of nucleated non-mammalian cells and blood matter |
-
1995
- 1995-02-21 EP EP95400358A patent/EP0668013B1/de not_active Expired - Lifetime
- 1995-02-21 DE DE69534151T patent/DE69534151T2/de not_active Expired - Fee Related
- 1995-02-21 US US08/390,957 patent/US5656498A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0668013A3 (de) | 1997-07-30 |
US5656498A (en) | 1997-08-12 |
DE69534151T2 (de) | 2006-01-12 |
EP0668013B1 (de) | 2005-04-20 |
EP0668013A2 (de) | 1995-08-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |