DE69532485D1 - Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung - Google Patents

Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung

Info

Publication number
DE69532485D1
DE69532485D1 DE69532485T DE69532485T DE69532485D1 DE 69532485 D1 DE69532485 D1 DE 69532485D1 DE 69532485 T DE69532485 T DE 69532485T DE 69532485 T DE69532485 T DE 69532485T DE 69532485 D1 DE69532485 D1 DE 69532485D1
Authority
DE
Germany
Prior art keywords
trehalose
production
dna coding
releasing enzyme
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69532485T
Other languages
English (en)
Other versions
DE69532485T2 (de
Inventor
Michio Kubota
Keiji Tsusaki
Kazuko Hattori
Toshiyuki Sugimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hayashibara Seibutsu Kagaku Kenkyujo KK
Original Assignee
Hayashibara Seibutsu Kagaku Kenkyujo KK
Hayashibara Biochemical Laboratories Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hayashibara Seibutsu Kagaku Kenkyujo KK, Hayashibara Biochemical Laboratories Co Ltd filed Critical Hayashibara Seibutsu Kagaku Kenkyujo KK
Publication of DE69532485D1 publication Critical patent/DE69532485D1/de
Application granted granted Critical
Publication of DE69532485T2 publication Critical patent/DE69532485T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/14Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/011414-Alpha-D-{(1->4)-alpha-D-glucano} trehalose trehalohydrolase (3.2.1.141)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69532485T 1994-03-07 1995-03-07 Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung Expired - Lifetime DE69532485T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP5983494 1994-03-07
JP5983494 1994-03-07
JP5984094 1994-03-07
JP5984094 1994-03-07

Publications (2)

Publication Number Publication Date
DE69532485D1 true DE69532485D1 (de) 2004-03-04
DE69532485T2 DE69532485T2 (de) 2004-11-04

Family

ID=26400910

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69532485T Expired - Lifetime DE69532485T2 (de) 1994-03-07 1995-03-07 Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung

Country Status (5)

Country Link
US (4) US5556781A (de)
EP (1) EP0671470B9 (de)
KR (1) KR100374449B1 (de)
DE (1) DE69532485T2 (de)
TW (2) TW494136B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556781A (en) * 1994-03-07 1996-09-17 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo DNA encoding enzyme, recombinant DNA and enzyme, transformant, and their preparations and uses
WO1995034642A1 (fr) * 1994-06-15 1995-12-21 Kirin Beer Kabushiki Kaisha Nouvelles transferase et amylase, procede de production de ces enzymes, utilisation, et genes les codant
JP3650632B2 (ja) * 1994-06-16 2005-05-25 株式会社林原生物化学研究所 マルトースをトレハロースに変換する組換え型酵素
US5985593A (en) * 1996-10-11 1999-11-16 Integrated Research Technology, L.L.C. Compositions and methods for enzymatic decontamination
JP4153057B2 (ja) * 1997-03-10 2008-09-17 中国化薬株式会社 D−グルクロノラクトンの製造方法
JPH11116588A (ja) 1997-10-16 1999-04-27 Hayashibara Biochem Lab Inc トレハロース及び糖アルコールの製造方法
JP4203159B2 (ja) 1997-12-09 2008-12-24 株式会社林原生物化学研究所 神経機能調節剤
JP4295840B2 (ja) * 1997-12-09 2009-07-15 株式会社林原生物化学研究所 血行改善剤
AU760216B2 (en) * 1998-09-11 2003-05-08 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Non-reducing saccharide-forming enzyme, trehalose-releasing enzyme, and process for producing saccharides using the same enzymes
JP3958884B2 (ja) * 1998-09-11 2007-08-15 株式会社林原生物化学研究所 非還元性糖質生成酵素及びトレハロース遊離酵素ならびに該酵素を用いる糖質の製造方法
JP4652540B2 (ja) 2000-03-02 2011-03-16 株式会社林原生物化学研究所 体臭抑制剤とその用途
CA2355814C (en) 2000-09-14 2010-06-29 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Pharmaceutical composition for ophthalmic use
US7259232B1 (en) * 2000-10-27 2007-08-21 Nymox Pharmaceutical Corporation Preferred segments of neural thread protein
JP4754066B2 (ja) 2000-12-22 2011-08-24 株式会社林原生物化学研究所 抗関節障害剤
CN1953755A (zh) * 2004-05-17 2007-04-25 株式会社林原生物化学研究所 强化接触水系环境的生物的生命活动和/或扩张生命活动适合区域的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5015448A (de) * 1973-06-08 1975-02-18
JPS50154485A (de) * 1974-05-31 1975-12-12
US4453931A (en) * 1980-08-01 1984-06-12 Oximetrix, Inc. Intravenous metering device
JPS582379A (ja) * 1981-06-29 1983-01-07 Natl House Ind Co Ltd 蓄断熱材
JPS5821669A (ja) * 1981-07-30 1983-02-08 Tetsuzo Kato 2−(1−アシルアミノアルキル)−6−メチル−4(3h)−ピリミジノンの製法
JPS5823799A (ja) * 1981-08-03 1983-02-12 株式会社林原生物化学研究所 高純度マルト−スの製造方法
JPS5872598A (ja) * 1981-10-26 1983-04-30 Hayashibara Biochem Lab Inc 高純度イソマルト−スの製造方法
JPS58216695A (ja) * 1982-06-07 1983-12-16 Otsuka Shokuhin Kogyo Kk トレハロ−スの製造方法
JPH05211882A (ja) * 1991-12-11 1993-08-24 Ajinomoto Co Inc トレハロースの製造法
ATE182359T1 (de) * 1992-12-28 1999-08-15 Hayashibara Biochem Lab Nichtreduzierendes saccharidbildendes enzym, und dessen herstellung und verwendungen
JP3559585B2 (ja) * 1993-06-03 2004-09-02 株式会社林原生物化学研究所 トレハロース遊離酵素とその製造方法並びに用途
US5556781A (en) * 1994-03-07 1996-09-17 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo DNA encoding enzyme, recombinant DNA and enzyme, transformant, and their preparations and uses

Also Published As

Publication number Publication date
US5834287A (en) 1998-11-10
US5556781A (en) 1996-09-17
US5830715A (en) 1998-11-03
KR100374449B1 (ko) 2003-09-06
KR950032624A (ko) 1995-12-22
EP0671470A2 (de) 1995-09-13
US5716813A (en) 1998-02-10
EP0671470B9 (de) 2004-11-03
DE69532485T2 (de) 2004-11-04
TW494136B (en) 2002-07-11
TW591109B (en) 2004-06-11
EP0671470B1 (de) 2004-01-28
EP0671470A3 (de) 1997-02-05

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