DE69530415D1 - Rekombinierte sequenzen des monoklonalen anti-idiotypischen antikörpers 3h1, diean dem menschlichen karzioembyonischen antigen liiert sind - Google Patents

Rekombinierte sequenzen des monoklonalen anti-idiotypischen antikörpers 3h1, diean dem menschlichen karzioembyonischen antigen liiert sind

Info

Publication number
DE69530415D1
DE69530415D1 DE69530415T DE69530415T DE69530415D1 DE 69530415 D1 DE69530415 D1 DE 69530415D1 DE 69530415 T DE69530415 T DE 69530415T DE 69530415 T DE69530415 T DE 69530415T DE 69530415 D1 DE69530415 D1 DE 69530415D1
Authority
DE
Germany
Prior art keywords
monoclonal anti
carcioembyonic
antique
listed
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69530415T
Other languages
English (en)
Other versions
DE69530415T2 (de
Inventor
Malaya Chatterjee
Heinz Kohler
K Chatterjee
A Foon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Kentucky
Original Assignee
University of Kentucky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Kentucky filed Critical University of Kentucky
Publication of DE69530415D1 publication Critical patent/DE69530415D1/de
Application granted granted Critical
Publication of DE69530415T2 publication Critical patent/DE69530415T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • C07K16/4266—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig against anti-tumor receptor Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/023—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a poxvirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69530415T 1994-12-28 1995-12-28 Rekombinierte sequenzen des monoklonalen anti-idiotypischen antikörpers 3h1, diean dem menschlichen karzioembyonischen antigen liiert sind Expired - Fee Related DE69530415T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36548494A 1994-12-28 1994-12-28
US365484 1994-12-28
PCT/US1995/017103 WO1996020277A2 (en) 1994-12-28 1995-12-28 Recombinant monoclonal anti-idiotype antibody 3h1 sequences relating to human carcinoembryonic antigen

Publications (2)

Publication Number Publication Date
DE69530415D1 true DE69530415D1 (de) 2003-05-22
DE69530415T2 DE69530415T2 (de) 2004-02-12

Family

ID=23439088

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69530107T Expired - Fee Related DE69530107T2 (de) 1994-12-28 1995-12-28 Monoklonaler anti-idiotypischer antikörper 3h1 aus maus
DE69530415T Expired - Fee Related DE69530415T2 (de) 1994-12-28 1995-12-28 Rekombinierte sequenzen des monoklonalen anti-idiotypischen antikörpers 3h1, diean dem menschlichen karzioembyonischen antigen liiert sind

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69530107T Expired - Fee Related DE69530107T2 (de) 1994-12-28 1995-12-28 Monoklonaler anti-idiotypischer antikörper 3h1 aus maus

Country Status (12)

Country Link
US (3) US7090842B1 (de)
EP (3) EP0796280B1 (de)
JP (2) JPH11500607A (de)
AT (2) ATE237687T1 (de)
AU (2) AU717779C (de)
CA (2) CA2209172C (de)
DE (2) DE69530107T2 (de)
DK (2) DK0800578T3 (de)
ES (2) ES2197217T3 (de)
MX (2) MX9704898A (de)
PT (2) PT796280E (de)
WO (2) WO1996020219A2 (de)

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US20020041872A1 (en) 1996-04-12 2002-04-11 Malaya Chatterjee Methods of delaying development of CEA-associated tumors using anti-idiotype antibody 3H1
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US6241985B1 (en) * 1996-05-15 2001-06-05 Altarex Corp. Method and composition for reconforming multi-epitopic antigens to initiate an immune response
US20080220012A1 (en) * 1996-05-15 2008-09-11 Ragupathy Madiyalakan Therapeutic Compositions that alter the immune response
US20020098190A1 (en) * 1997-06-13 2002-07-25 Malaya Chatterjee Compositions and methods for treating tumors bearing HMFG and CEA antigens
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AT409086B (de) * 1999-11-16 2002-05-27 Igeneon Krebs Immuntherapie Neue verwendung von antikörpern als impfstoffe
US6774209B1 (en) 2000-04-03 2004-08-10 Dyax Corp. Binding peptides for carcinoembryonic antigen (CEA)
US8101200B2 (en) 2000-04-13 2012-01-24 Angiotech Biocoatings, Inc. Targeted therapeutic agent release devices and methods of making and using the same
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US8029803B2 (en) * 2002-06-20 2011-10-04 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8025873B2 (en) 2002-06-20 2011-09-27 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
AT500650B1 (de) * 2003-04-17 2009-11-15 Altropus Gmbh Immunogener rekombinanter antikörper
US8007805B2 (en) * 2003-08-08 2011-08-30 Paladin Labs, Inc. Chimeric antigens for breaking host tolerance to foreign antigens
CN101005941B (zh) * 2004-08-05 2010-06-16 R&D绿色材料公司 用于制造固体可生物降解制品的低温模塑方法
AU2005309434A1 (en) * 2004-11-24 2006-06-01 Board Of Regents, The University Of Texas System Method for identifying and designing immunogenic peptides
CN101300355A (zh) * 2005-10-13 2008-11-05 威瑞克斯医药公司 包含丙型肝炎病毒多肽和用于引起免疫应答的Fc片段的嵌合抗原
JP5165672B2 (ja) * 2006-03-29 2013-03-21 キングス カレッジ ロンドン Ｔｓｈｒに対するアゴニスト抗体
TWI434855B (zh) * 2006-11-21 2014-04-21 Hoffmann La Roche 結合物及其在免疫分析中作為參考標準之用途
CA2700197C (en) 2007-11-08 2020-09-08 Neogenix Oncology, Inc. Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers
US8093018B2 (en) * 2008-05-20 2012-01-10 Otsuka Pharmaceutical Co., Ltd. Antibody identifying an antigen-bound antibody and an antigen-unbound antibody, and method for preparing the same
KR101761541B1 (ko) * 2009-10-26 2017-07-26 네스텍 소시에테아노님 항-ｔｎｆ 약물 및 자가항체의 검출을 위한 검정법
AU2011317149B2 (en) 2010-10-18 2015-05-07 Société des Produits Nestlé S.A. Methods for determining anti-drug antibody isotypes
JP6181646B2 (ja) 2011-07-06 2017-08-16 ネステク ソシエテ アノニム Ｔｎｆアルファによる生物学的治療に対する中和自己抗体の検出のためのアッセイ
MA40094B1 (fr) * 2014-08-06 2022-05-31 Univ Miami Protéines de fusion de l'interleukine-2/récepteur alpha de l'interleukine-2 et procédés d'utilisation
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Also Published As

Publication number Publication date
PT796280E (pt) 2003-08-29
JPH11500607A (ja) 1999-01-19
ATE237687T1 (de) 2003-05-15
PT800578E (pt) 2003-09-30
DE69530107T2 (de) 2003-10-16
AU4692796A (en) 1996-07-19
ES2196098T3 (es) 2003-12-16
ES2197217T3 (es) 2004-01-01
AU4649896A (en) 1996-07-19
AU717779C (en) 2002-12-05
WO1996020277A2 (en) 1996-07-04
EP1298144A2 (de) 2003-04-02
WO1996020219A3 (en) 1996-09-06
US5977315A (en) 1999-11-02
EP0800578A2 (de) 1997-10-15
EP0800578B1 (de) 2003-04-16
EP0796280A2 (de) 1997-09-24
CA2209360C (en) 2010-07-06
JPH10511846A (ja) 1998-11-17
DK0800578T3 (da) 2003-08-11
WO1996020219A2 (en) 1996-07-04
US7090842B1 (en) 2006-08-15
MX9704897A (es) 1998-06-28
DK0796280T3 (da) 2003-04-22
EP0796280B1 (de) 2003-03-26
EP1298144A3 (de) 2006-05-31
AU704829B2 (en) 1999-05-06
DE69530107D1 (de) 2003-04-30
ATE235514T1 (de) 2003-04-15
MX9704898A (es) 1998-06-28
CA2209172C (en) 2007-04-10
WO1996020277A3 (en) 1996-09-06
CA2209360A1 (en) 1996-07-04
DE69530415T2 (de) 2004-02-12
AU717779B2 (en) 2000-03-30
CA2209172A1 (en) 1996-07-04
US20010047083A1 (en) 2001-11-29

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