DE69524405D1 - Photometrische Durchflussvorrichtung für kleine Probenvolumina - Google Patents

Photometrische Durchflussvorrichtung für kleine Probenvolumina

Info

Publication number
DE69524405D1
DE69524405D1 DE69524405T DE69524405T DE69524405D1 DE 69524405 D1 DE69524405 D1 DE 69524405D1 DE 69524405 T DE69524405 T DE 69524405T DE 69524405 T DE69524405 T DE 69524405T DE 69524405 D1 DE69524405 D1 DE 69524405D1
Authority
DE
Germany
Prior art keywords
flow device
small sample
sample volumes
photometric flow
photometric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69524405T
Other languages
English (en)
Other versions
DE69524405T2 (de
Inventor
Patrick Kaltenbach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agilent Technologies Deutschland GmbH
Original Assignee
Agilent Technologies Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agilent Technologies Deutschland GmbH filed Critical Agilent Technologies Deutschland GmbH
Publication of DE69524405D1 publication Critical patent/DE69524405D1/de
Application granted granted Critical
Publication of DE69524405T2 publication Critical patent/DE69524405T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N21/05—Flow-through cuvettes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/74—Optical detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/74—Optical detectors
    • G01N2030/746—Optical detectors detecting along the line of flow, e.g. axial
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/064—Stray light conditioning
    • G01N2201/0642—Light traps; baffles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optical Measuring Cells (AREA)
DE69524405T 1995-09-06 1995-09-06 Photometrische Durchflussvorrichtung für kleine Probenvolumina Expired - Lifetime DE69524405T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95113947A EP0762119B1 (de) 1995-09-06 1995-09-06 Photometrische Durchflussvorrichtung für kleine Probenvolumina

Publications (2)

Publication Number Publication Date
DE69524405D1 true DE69524405D1 (de) 2002-01-17
DE69524405T2 DE69524405T2 (de) 2002-05-23

Family

ID=8219582

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69524405T Expired - Lifetime DE69524405T2 (de) 1995-09-06 1995-09-06 Photometrische Durchflussvorrichtung für kleine Probenvolumina

Country Status (4)

Country Link
US (1) US5917606A (de)
EP (1) EP0762119B1 (de)
JP (1) JPH09170981A (de)
DE (1) DE69524405T2 (de)

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US6224830B1 (en) 1998-01-30 2001-05-01 The Governors Of The University Of Alberta Absorbance cell for microfluid devices
US6075609A (en) * 1998-03-26 2000-06-13 Antek Industrial Instruments, Inc. Apparatus and methods for improving fluorescence detectors
US6188813B1 (en) * 1999-02-10 2001-02-13 Waters Investments Limited Flow cell, analyte measurement apparatus and methods related thereto
JP2001108619A (ja) * 1999-10-12 2001-04-20 Minolta Co Ltd 分析装置、試料操作針および試料取り出し方法
US6678051B2 (en) 2001-01-18 2004-01-13 Systec, Inc. Flow cells utilizing photometric techniques
JP3844738B2 (ja) 2001-03-02 2006-11-15 ウォーターズ・インヴェストメンツ・リミテッド 蛍光検知器構造
US20030110840A1 (en) * 2001-07-24 2003-06-19 Arriaga Edgar A. Systems and methods for detecting a particle
US7250098B2 (en) * 2001-09-28 2007-07-31 Applera Corporation Multi-capillary array electrophoresis device
WO2003027028A1 (en) * 2001-09-28 2003-04-03 Applera Corporation Multi-capillary array electrophoresis device
US7294839B2 (en) * 2002-10-08 2007-11-13 Ric Investements, Inc. Low volume sample cell and gas monitoring system using same
US6987897B2 (en) * 2002-10-31 2006-01-17 Luna Innovations Incorporated Fiber-optic flow cell and method relating thereto
AU2002952602A0 (en) * 2002-11-12 2002-11-28 Varian Australia Pty Ltd Flow through cell for optical spectroscopy
JP4005907B2 (ja) * 2002-12-12 2007-11-14 株式会社日立ハイテクノロジーズ キャピラリアレイ装置、その製造方法、及び電気泳動分析方法
US7050660B2 (en) 2003-04-07 2006-05-23 Eksigent Technologies Llc Microfluidic detection device having reduced dispersion and method for making same
US7894055B2 (en) * 2004-08-26 2011-02-22 The United States Of America As Represented By The Department Of Health And Human Services Flow-through, inlet-gas-temperature-controlled, solvent-resistant, thermal-expansion compensated cell for light spectroscopy
JP2006078414A (ja) * 2004-09-13 2006-03-23 Alps Electric Co Ltd 検査用プレート
US20060094004A1 (en) * 2004-10-28 2006-05-04 Akihisa Nakajima Micro-reactor, biological material inspection device, and microanalysis system
WO2006056236A1 (en) * 2004-11-25 2006-06-01 Agilent Technologies, Inc. Microfluidic arrangement with coupling device having a selectable optical detection portion
US7298472B2 (en) * 2004-12-28 2007-11-20 Rheodyne, Llc Fluid analysis apparatus
US7259840B1 (en) 2004-12-28 2007-08-21 Systec, Llc Fluid analysis apparatus
US7386199B2 (en) * 2005-12-22 2008-06-10 Palo Alto Research Center Incorporated Providing light to channels or portions
JP4781827B2 (ja) * 2006-01-24 2011-09-28 シャープ株式会社 分析方法および分析装置
CN100419406C (zh) * 2006-03-31 2008-09-17 洪陵成 流动光度分析流通池
US7545490B1 (en) * 2006-09-26 2009-06-09 Itt Manufacturing Enterprises, Inc. Microscope flow cell apparatus for raman analysis of a liquid
US9164037B2 (en) * 2007-01-26 2015-10-20 Palo Alto Research Center Incorporated Method and system for evaluation of signals received from spatially modulated excitation and emission to accurately determine particle positions and distances
US8821799B2 (en) 2007-01-26 2014-09-02 Palo Alto Research Center Incorporated Method and system implementing spatially modulated excitation or emission for particle characterization with enhanced sensitivity
US8629981B2 (en) * 2008-02-01 2014-01-14 Palo Alto Research Center Incorporated Analyzers with time variation based on color-coded spatial modulation
GB2457481B (en) * 2008-02-14 2012-08-08 Starna Scient Ltd Fluorescence measurement cell
GB2473787A (en) 2008-08-07 2011-03-23 Agilent Technologies Inc Multi-wavelength light source
DE102009025073A1 (de) * 2009-06-16 2010-12-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Optischer Sensor
US8502969B2 (en) * 2009-12-16 2013-08-06 Boule Medical Ab Miniature flow-through cuvette and spectrophotometer containing the same
JP5854621B2 (ja) * 2011-04-07 2016-02-09 株式会社日立ハイテクノロジーズ 長光路長フローセル
US8723140B2 (en) 2011-08-09 2014-05-13 Palo Alto Research Center Incorporated Particle analyzer with spatial modulation and long lifetime bioprobes
US9029800B2 (en) 2011-08-09 2015-05-12 Palo Alto Research Center Incorporated Compact analyzer with spatial modulation and multiple intensity modulated excitation sources
DE102013013975B3 (de) 2013-08-23 2014-12-04 SunChrom Wissenschaftliche Geräte GmbH UV/VlS HPLC-Photometer
US10451593B2 (en) * 2016-08-04 2019-10-22 Aa Holdings, Ltd. Detection system and method with nanostructure flow cell
WO2018037536A1 (ja) * 2016-08-25 2018-03-01 株式会社島津製作所 フローセル
US11422117B2 (en) * 2018-08-30 2022-08-23 KNAUER Wissenschaftliche Geräte GmbH Combined UV/Vis-absorption and conductivity flow cell for liquid chromatography

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3783276A (en) * 1972-06-05 1974-01-01 Instrumentation Specialties Co Dual beam optical system
US3751173A (en) * 1972-08-24 1973-08-07 Micromedic Systems Inc Flowthrough cuvette
US4575424A (en) * 1984-03-01 1986-03-11 Isco, Inc. Chromatographic flow cell and method of making it
JPS63241337A (ja) * 1986-11-07 1988-10-06 Hitachi Ltd 光度計用フローセル
US5061361A (en) * 1989-03-06 1991-10-29 Hewlett-Packard Company Capillary zone electrophoresis cell system
DE69006091T2 (de) * 1989-04-14 1994-05-05 Kontron Instr Holding Kapillare Durchflusszelle.
DE4030699C1 (de) * 1990-09-28 1991-10-10 Bruker Analytische Messtechnik Gmbh, 7512 Rheinstetten, De
DE59104604D1 (de) * 1990-11-26 1995-03-23 Ciba Geigy Ag Detektorzelle.
US5184192A (en) * 1991-07-17 1993-02-02 Millipore Corporation Photometric apparatus with a flow cell coated with an amorphous fluoropolymer
US5273633A (en) * 1992-07-10 1993-12-28 Tiansong Wang Capillary multireflective cell
GB9314926D0 (en) * 1993-07-19 1993-09-01 Optiglass Ltd Spectrophotometer cell

Also Published As

Publication number Publication date
EP0762119A1 (de) 1997-03-12
US5917606A (en) 1999-06-29
EP0762119B1 (de) 2001-12-05
JPH09170981A (ja) 1997-06-30
DE69524405T2 (de) 2002-05-23

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