DE69522490D1 - Platinkomplexe - Google Patents
PlatinkomplexeInfo
- Publication number
- DE69522490D1 DE69522490D1 DE69522490T DE69522490T DE69522490D1 DE 69522490 D1 DE69522490 D1 DE 69522490D1 DE 69522490 T DE69522490 T DE 69522490T DE 69522490 T DE69522490 T DE 69522490T DE 69522490 D1 DE69522490 D1 DE 69522490D1
- Authority
- DE
- Germany
- Prior art keywords
- platinum complexes
- cycloalkyl
- aryl
- alkyl
- different
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000003057 platinum Chemical class 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000000852 hydrogen donor Substances 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 125000002577 pseudohalo group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Photolithography (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9408218A GB9408218D0 (en) | 1994-04-26 | 1994-04-26 | Improvements in platinum complexes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69522490D1 true DE69522490D1 (de) | 2001-10-11 |
| DE69522490T2 DE69522490T2 (de) | 2002-05-16 |
Family
ID=10754111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69522490T Expired - Lifetime DE69522490T2 (de) | 1994-04-26 | 1995-04-20 | Platinkomplexe |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5519155A (de) |
| EP (1) | EP0679656B1 (de) |
| JP (1) | JPH0840892A (de) |
| AT (1) | ATE205216T1 (de) |
| AU (1) | AU692521B2 (de) |
| CA (1) | CA2147567C (de) |
| DE (1) | DE69522490T2 (de) |
| DK (1) | DK0679656T3 (de) |
| ES (1) | ES2162897T3 (de) |
| GB (1) | GB9408218D0 (de) |
| GR (1) | GR3036538T3 (de) |
| PT (1) | PT679656E (de) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9502799D0 (en) * | 1995-02-14 | 1995-04-05 | Johnson Matthey Plc | Improvements in platinum complexes |
| EP2289549A3 (de) | 1999-10-01 | 2011-06-15 | Immunogen, Inc. | Immunokonjugate für Krebsbehandlung |
| GB0011903D0 (en) * | 2000-05-18 | 2000-07-05 | Astrazeneca Ab | Combination chemotherapy |
| US7138520B2 (en) * | 2003-01-13 | 2006-11-21 | Massachusetts Institute Of Technology | Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same |
| WO2005077385A2 (en) | 2004-02-18 | 2005-08-25 | Gpc Biotech Ag | Methods for treating resistant or refractory tumors |
| US20080146555A1 (en) | 2004-06-18 | 2008-06-19 | Gpc Biotech, Inc | Uses of Kinase Inhibitors and Compositions Thereof |
| EP1781230A1 (de) * | 2004-07-14 | 2007-05-09 | GPC Biotech AG | Verpackungssystem für variable dosierung |
| US8168662B1 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8173686B2 (en) | 2006-11-06 | 2012-05-08 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8168661B2 (en) * | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US8178564B2 (en) * | 2006-11-06 | 2012-05-15 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
| US20110033528A1 (en) * | 2009-08-05 | 2011-02-10 | Poniard Pharmaceuticals, Inc. | Stabilized picoplatin oral dosage form |
| US20100260832A1 (en) * | 2007-06-27 | 2010-10-14 | Poniard Pharmaceuticals, Inc. | Combination therapy for ovarian cancer |
| TW200916094A (en) * | 2007-06-27 | 2009-04-16 | Poniard Pharmaceuticals Inc | Stabilized picoplatin dosage form |
| US20100310661A1 (en) * | 2007-07-16 | 2010-12-09 | Poniard Pharmaceuticals, Inc. | Oral formulations for picoplatin |
| WO2009032172A2 (en) * | 2007-08-31 | 2009-03-12 | Massachusetts Institute Of Technology | Platinum compositions as treatment for oct-related cancers |
| EP2244714A4 (de) * | 2008-02-08 | 2012-06-06 | Poniard Pharmaceuticals Inc | Verwendung von picoplatin und bevacizumab zur behandlung von kolorektalkarzinom |
| US9265747B2 (en) | 2008-08-26 | 2016-02-23 | Massachusetts Institute Of Technology | Platinum (IV) complexes for use in dual mode pharmaceutical therapy |
| WO2010149666A1 (en) | 2009-06-22 | 2010-12-29 | Medexis S.A. | Methods for treating neoplasia |
| US20120238488A1 (en) | 2009-09-08 | 2012-09-20 | Konstantinos Alevizopoulos | Compounds and methods for treating neoplasia |
| WO2012013816A1 (en) | 2010-07-30 | 2012-02-02 | Medexis S.A. | Compounds and methods for treating neoplasia |
| WO2012177935A1 (en) | 2011-06-21 | 2012-12-27 | Massachusetts Inistitute Of Technology | Compositions and methods for the treatment of cancer |
| US8729286B2 (en) | 2012-05-10 | 2014-05-20 | Massachusetts Institute Of Technology | Platinum compounds as treatment for cancers, and related methods, kits, and compositions |
| US9133225B2 (en) | 2013-03-13 | 2015-09-15 | Massachusetts Institute Of Technology | Dual targeting anticancer agents |
| WO2014165782A2 (en) | 2013-04-05 | 2014-10-09 | Massachusetts Institute Of Technology | Compositions, methods, and kits comprising platinum compounds associated with a ligand comprising a targeting moiety |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE113054T1 (de) * | 1988-02-02 | 1994-11-15 | Johnson Matthey Inc | Pt(iv) komplexe. |
-
1994
- 1994-04-26 GB GB9408218A patent/GB9408218D0/en active Pending
-
1995
- 1995-04-20 DK DK95302629T patent/DK0679656T3/da active
- 1995-04-20 ES ES95302629T patent/ES2162897T3/es not_active Expired - Lifetime
- 1995-04-20 DE DE69522490T patent/DE69522490T2/de not_active Expired - Lifetime
- 1995-04-20 PT PT95302629T patent/PT679656E/pt unknown
- 1995-04-20 AT AT95302629T patent/ATE205216T1/de active
- 1995-04-20 EP EP95302629A patent/EP0679656B1/de not_active Expired - Lifetime
- 1995-04-21 CA CA002147567A patent/CA2147567C/en not_active Expired - Lifetime
- 1995-04-24 AU AU17661/95A patent/AU692521B2/en not_active Expired
- 1995-04-25 JP JP7100870A patent/JPH0840892A/ja active Pending
- 1995-04-25 US US08/428,444 patent/US5519155A/en not_active Expired - Lifetime
-
2001
- 2001-09-06 GR GR20010401212T patent/GR3036538T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5519155A (en) | 1996-05-21 |
| CA2147567A1 (en) | 1995-10-27 |
| GR3036538T3 (en) | 2001-12-31 |
| AU1766195A (en) | 1995-11-02 |
| EP0679656A1 (de) | 1995-11-02 |
| JPH0840892A (ja) | 1996-02-13 |
| DE69522490T2 (de) | 2002-05-16 |
| GB9408218D0 (en) | 1994-06-15 |
| PT679656E (pt) | 2001-12-28 |
| DK0679656T3 (da) | 2001-10-01 |
| EP0679656B1 (de) | 2001-09-05 |
| ATE205216T1 (de) | 2001-09-15 |
| ES2162897T3 (es) | 2002-01-16 |
| AU692521B2 (en) | 1998-06-11 |
| CA2147567C (en) | 2006-01-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |