DK0679656T3 - Forbedringer af platinkomplekser - Google Patents
Forbedringer af platinkomplekserInfo
- Publication number
- DK0679656T3 DK0679656T3 DK95302629T DK95302629T DK0679656T3 DK 0679656 T3 DK0679656 T3 DK 0679656T3 DK 95302629 T DK95302629 T DK 95302629T DK 95302629 T DK95302629 T DK 95302629T DK 0679656 T3 DK0679656 T3 DK 0679656T3
- Authority
- DK
- Denmark
- Prior art keywords
- enhancements
- platinum complexes
- cycloalkyl
- aryl
- alkyl
- Prior art date
Links
- 150000003057 platinum Chemical class 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 239000000852 hydrogen donor Substances 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 125000002577 pseudohalo group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Photolithography (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9408218A GB9408218D0 (en) | 1994-04-26 | 1994-04-26 | Improvements in platinum complexes |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0679656T3 true DK0679656T3 (da) | 2001-10-01 |
Family
ID=10754111
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK95302629T DK0679656T3 (da) | 1994-04-26 | 1995-04-20 | Forbedringer af platinkomplekser |
Country Status (12)
Country | Link |
---|---|
US (1) | US5519155A (da) |
EP (1) | EP0679656B1 (da) |
JP (1) | JPH0840892A (da) |
AT (1) | ATE205216T1 (da) |
AU (1) | AU692521B2 (da) |
CA (1) | CA2147567C (da) |
DE (1) | DE69522490T2 (da) |
DK (1) | DK0679656T3 (da) |
ES (1) | ES2162897T3 (da) |
GB (1) | GB9408218D0 (da) |
GR (1) | GR3036538T3 (da) |
PT (1) | PT679656E (da) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9502799D0 (en) * | 1995-02-14 | 1995-04-05 | Johnson Matthey Plc | Improvements in platinum complexes |
CA2385528C (en) | 1999-10-01 | 2013-12-10 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
GB0011903D0 (en) * | 2000-05-18 | 2000-07-05 | Astrazeneca Ab | Combination chemotherapy |
US7138520B2 (en) * | 2003-01-13 | 2006-11-21 | Massachusetts Institute Of Technology | Coordination complexes having tethered therapeutic agents and/or targeting moieties, and methods of making and using the same |
PT1720540E (pt) | 2004-02-18 | 2008-09-10 | Gpc Biotech Ag | Métodos de tratamento de tumores resistentes ou refractários |
CA2584493A1 (en) | 2004-06-18 | 2006-01-05 | Gpc Biotech, Inc. | Kinase inhibitors for treating cancers |
JP2008506463A (ja) * | 2004-07-14 | 2008-03-06 | ゲーペーツェー ビオテック アーゲー | 可変投与量パッケージシステム |
US8173686B2 (en) | 2006-11-06 | 2012-05-08 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8168661B2 (en) * | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8178564B2 (en) * | 2006-11-06 | 2012-05-15 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US8168662B1 (en) | 2006-11-06 | 2012-05-01 | Poniard Pharmaceuticals, Inc. | Use of picoplatin to treat colorectal cancer |
US20110033528A1 (en) * | 2009-08-05 | 2011-02-10 | Poniard Pharmaceuticals, Inc. | Stabilized picoplatin oral dosage form |
TW200916094A (en) * | 2007-06-27 | 2009-04-16 | Poniard Pharmaceuticals Inc | Stabilized picoplatin dosage form |
US20100260832A1 (en) * | 2007-06-27 | 2010-10-14 | Poniard Pharmaceuticals, Inc. | Combination therapy for ovarian cancer |
CN101809024A (zh) * | 2007-07-16 | 2010-08-18 | 铂雅制药公司 | 吡铂的口服制剂 |
WO2009032172A2 (en) * | 2007-08-31 | 2009-03-12 | Massachusetts Institute Of Technology | Platinum compositions as treatment for oct-related cancers |
US20110053879A1 (en) * | 2008-02-08 | 2011-03-03 | Poniard Pharmaceuticals, Inc. | Picoplatin and amrubicin to treat lung cancer |
US9265747B2 (en) | 2008-08-26 | 2016-02-23 | Massachusetts Institute Of Technology | Platinum (IV) complexes for use in dual mode pharmaceutical therapy |
WO2010149666A1 (en) | 2009-06-22 | 2010-12-29 | Medexis S.A. | Methods for treating neoplasia |
US20120238488A1 (en) | 2009-09-08 | 2012-09-20 | Konstantinos Alevizopoulos | Compounds and methods for treating neoplasia |
US20130303500A1 (en) | 2010-07-30 | 2013-11-14 | Medexis S.A. | Compounds and methods for treating neoplasia |
US9034862B2 (en) | 2011-06-21 | 2015-05-19 | Massachusetts Institute Of Technology | Compositions and methods for the treatment of cancer |
US8729286B2 (en) | 2012-05-10 | 2014-05-20 | Massachusetts Institute Of Technology | Platinum compounds as treatment for cancers, and related methods, kits, and compositions |
US9133225B2 (en) | 2013-03-13 | 2015-09-15 | Massachusetts Institute Of Technology | Dual targeting anticancer agents |
US9593139B2 (en) | 2013-04-05 | 2017-03-14 | Massachusetts Institute Of Technology | Compositions, methods, and kits comprising platinum compounds associated with a ligand comprising a targeting moiety |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0328274B1 (en) * | 1988-02-02 | 1994-10-19 | Johnson Matthey, Inc., | Pt (IV) complexes |
-
1994
- 1994-04-26 GB GB9408218A patent/GB9408218D0/en active Pending
-
1995
- 1995-04-20 AT AT95302629T patent/ATE205216T1/de active
- 1995-04-20 DE DE69522490T patent/DE69522490T2/de not_active Expired - Lifetime
- 1995-04-20 DK DK95302629T patent/DK0679656T3/da active
- 1995-04-20 PT PT95302629T patent/PT679656E/pt unknown
- 1995-04-20 EP EP95302629A patent/EP0679656B1/en not_active Expired - Lifetime
- 1995-04-20 ES ES95302629T patent/ES2162897T3/es not_active Expired - Lifetime
- 1995-04-21 CA CA002147567A patent/CA2147567C/en not_active Expired - Lifetime
- 1995-04-24 AU AU17661/95A patent/AU692521B2/en not_active Expired
- 1995-04-25 JP JP7100870A patent/JPH0840892A/ja active Pending
- 1995-04-25 US US08/428,444 patent/US5519155A/en not_active Expired - Lifetime
-
2001
- 2001-09-06 GR GR20010401212T patent/GR3036538T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0679656A1 (en) | 1995-11-02 |
ATE205216T1 (de) | 2001-09-15 |
US5519155A (en) | 1996-05-21 |
CA2147567A1 (en) | 1995-10-27 |
AU692521B2 (en) | 1998-06-11 |
GR3036538T3 (en) | 2001-12-31 |
ES2162897T3 (es) | 2002-01-16 |
AU1766195A (en) | 1995-11-02 |
GB9408218D0 (en) | 1994-06-15 |
PT679656E (pt) | 2001-12-28 |
CA2147567C (en) | 2006-01-17 |
JPH0840892A (ja) | 1996-02-13 |
DE69522490D1 (de) | 2001-10-11 |
DE69522490T2 (de) | 2002-05-16 |
EP0679656B1 (en) | 2001-09-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0679656T3 (da) | Forbedringer af platinkomplekser | |
NO890426L (no) | Platina(iv)komplekser. | |
Korytowski et al. | Mechanism of dismutation of superoxide produced during autoxidation of melanin pigments | |
DK459086A (da) | Quinazolinderivater | |
TR200000482T2 (tr) | N-Aroilfenilalanin türevleri. | |
NO960569D0 (no) | Forbedringer i platina-komplekser | |
DE59108419D1 (de) | Dicarbonsäureimide, Verfahren zu ihrer Herstellung und ihre Verwendung als Herbizide | |
NO20022976D0 (no) | 2-(1H-indol-3yl)-2-okso-acetamider med antitumoraktivitet | |
ES2013035A6 (es) | Un metodo para preparar derivados de acilfenol. | |
BG99369A (en) | Derivatives of 2-imidazoline-5-on and 2-imidazoline-5-thion of fungicide activity | |
TR199700354A2 (xx) | Karbohidrat t�revleri. | |
ATE86246T1 (de) | Schwefelhaltige oximether und diese enthaltende fungizide. | |
ATE226426T1 (de) | Triazinderivate enthaltendes sonnenschutzmittel | |
DE69215881D1 (de) | Färbemittel auf basis von hydroxyindolinderivaten | |
TH2764A (th) | N-ฟอสฟอริล-หรือ N-ไธโอฟอสฟอริล-N'-s-ไตรอาซินิล-ฟอร์มามิดีนชนิดใหม่ | |
TH2764EX (th) | N-ฟอสฟอริล-หรือ N-ไธโอฟอสฟอริล-N'-s-ไตรอาซินิล-ฟอร์มามิดีนชนิดใหม่ |