DE69522456T2 - Stabiles vitamin a - Google Patents

Stabiles vitamin a

Info

Publication number
DE69522456T2
DE69522456T2 DE69522456T DE69522456T DE69522456T2 DE 69522456 T2 DE69522456 T2 DE 69522456T2 DE 69522456 T DE69522456 T DE 69522456T DE 69522456 T DE69522456 T DE 69522456T DE 69522456 T2 DE69522456 T2 DE 69522456T2
Authority
DE
Germany
Prior art keywords
vitamin
tocopherol
encapsulated
parts
less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69522456T
Other languages
English (en)
Other versions
DE69522456D1 (de
Inventor
Joseph Sarama
Joseph Wehmeier
Robert Sevenants
Alan Sanders
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/285,242 external-priority patent/US5426248A/en
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of DE69522456D1 publication Critical patent/DE69522456D1/de
Application granted granted Critical
Publication of DE69522456T2 publication Critical patent/DE69522456T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07Retinol compounds, e.g. vitamin A
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/12Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by esterified hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
DE69522456T 1994-08-03 1995-06-09 Stabiles vitamin a Expired - Lifetime DE69522456T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/285,242 US5426248A (en) 1994-08-03 1994-08-03 Stable vitamin A
US08/438,869 US5648091A (en) 1994-08-03 1995-05-23 Stable vitamin A encapsulated
PCT/US1995/007419 WO1996004243A1 (en) 1994-08-03 1995-06-09 Stable vitamin a

Publications (2)

Publication Number Publication Date
DE69522456D1 DE69522456D1 (de) 2001-10-04
DE69522456T2 true DE69522456T2 (de) 2002-05-02

Family

ID=26963088

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69522456T Expired - Lifetime DE69522456T2 (de) 1994-08-03 1995-06-09 Stabiles vitamin a

Country Status (18)

Country Link
US (1) US5648091A (de)
EP (1) EP0775111B1 (de)
JP (1) JP2960547B2 (de)
KR (1) KR100244067B1 (de)
CN (1) CN1072646C (de)
AT (1) ATE204858T1 (de)
AU (1) AU704286B2 (de)
BR (1) BR9508508A (de)
CA (1) CA2196295C (de)
CZ (1) CZ293262B6 (de)
DE (1) DE69522456T2 (de)
ES (1) ES2159643T3 (de)
FI (1) FI970425A (de)
HU (1) HUT76799A (de)
MX (1) MX9700841A (de)
NO (1) NO970429L (de)
NZ (1) NZ288880A (de)
WO (1) WO1996004243A1 (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023161203A1 (en) * 2022-02-22 2023-08-31 Dsm Ip Assets B.V. Retinol formulation (iv)
WO2023161201A1 (en) * 2022-02-22 2023-08-31 Dsm Ip Assets B.V. Retinol formulation (vi)
WO2023161200A1 (en) * 2022-02-22 2023-08-31 Dsm Ip Assets B.V. Retinol formulation (v)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030008919A1 (en) * 1999-06-03 2003-01-09 Jean-Baptiste Roullet Use of retinoids to treat high blood pressure and other cardiovascular disease
CO5011072A1 (es) * 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores
WO2002043779A2 (en) * 2000-12-01 2002-06-06 Auburn University Use of acacia gum (arabic gum) to isolate and preserve biological material
US7604807B2 (en) * 2000-12-01 2009-10-20 Auburn University Use of pullulan to isolate and preserve biological material
KR20030070798A (ko) * 2002-02-26 2003-09-02 주식회사 국순당 다당류 및 단백질 물질로 미세캡슐화된 지용성 항산화제및 그의 제조 방법
US20030232091A1 (en) * 2002-06-17 2003-12-18 Adi Shefer Stabilized retinol for cosmetic dermatological, and pharmaceutical compositions, and use thereof
US9186640B2 (en) * 2007-08-28 2015-11-17 Pepsico, Inc. Delivery and controlled release of encapsulated lipophilic nutrients
JP5728152B2 (ja) * 2008-07-07 2015-06-03 株式会社ファンケル 乾燥リポソーム製剤
US9173818B2 (en) * 2011-03-25 2015-11-03 Zhejiang Nhu Company Ltd Method for preparing stable-type vitamin A microcapsules continuously
KR102157407B1 (ko) 2013-08-15 2020-09-17 마리 케이 인코포레이티드 주름 치료를 위한 국소 피부 조성물
CN115003171A (zh) * 2019-11-15 2022-09-02 巴斯夫欧洲公司 食品添加剂和其制备方法
CN112841319B (zh) * 2021-02-09 2021-11-19 赣州市全标生物科技有限公司 一种全程氮气介导下的婴幼儿辅食营养包与其制备方法
CN113016875B (zh) * 2021-02-09 2021-11-19 赣州市全标生物科技有限公司 一种氮气介导三级稳态保护的婴幼儿辅食营养包与其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2777797A (en) * 1952-06-04 1957-01-15 Nopco Chem Co Vitamin products
US2828206A (en) * 1954-02-24 1958-03-25 Roseuberg Adolf Stabilized fat-soluble vitamins and methods of making same
FR1425252A (fr) * 1956-09-26 1966-01-24 Eastman Kodak Co Compositions stables à base de vitamines a ou de ses dérivés et stabilisant pour cette composition
GB887813A (en) * 1958-03-12 1962-01-24 Commercial Solvents Corp Vitamin containing compositions and methods of producing them
US3067104A (en) * 1958-09-17 1962-12-04 Nopco Chem Co Stable fat-soluble vitamin compositions
US3067105A (en) * 1959-09-22 1962-12-04 Nopco Chem Co Vitamin compositions and processes for producing same
US3949006A (en) * 1972-04-24 1976-04-06 Scm Corporation Synthesis of vitamin A, intermediates and conversion thereof to vitamin A
DE3578169D1 (de) * 1985-01-10 1990-07-19 Kuraray Co Verfahren zur herstellung von vitamin a oder seinen carbonsaeureestern und zwischenprodukte und ihre verwendung in diesem verfahren.
FR2623805B1 (fr) * 1987-12-01 1990-04-13 Rhone Poulenc Sante Procede de preparation de la vitamine a
AU8904391A (en) * 1990-12-19 1992-07-22 Unilever Plc Edible fat-containing products containing vitamin e
US5521221A (en) * 1991-04-09 1996-05-28 Sloan-Kettering Institute For Cancer Research Retro-α-retinol (4,14-retro-retinol) derivatives and uses of retro-α-retinol
US5426248A (en) * 1994-08-03 1995-06-20 The Procter & Gamble Company Stable vitamin A

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023161203A1 (en) * 2022-02-22 2023-08-31 Dsm Ip Assets B.V. Retinol formulation (iv)
WO2023161201A1 (en) * 2022-02-22 2023-08-31 Dsm Ip Assets B.V. Retinol formulation (vi)
WO2023161200A1 (en) * 2022-02-22 2023-08-31 Dsm Ip Assets B.V. Retinol formulation (v)

Also Published As

Publication number Publication date
ES2159643T3 (es) 2001-10-16
AU704286B2 (en) 1999-04-15
DE69522456D1 (de) 2001-10-04
MX9700841A (es) 1997-04-30
BR9508508A (pt) 1998-06-02
CZ293262B6 (cs) 2004-03-17
FI970425A0 (fi) 1997-01-31
WO1996004243A1 (en) 1996-02-15
EP0775111B1 (de) 2001-08-29
CA2196295C (en) 2003-01-28
KR100244067B1 (ko) 2000-03-02
HUT76799A (en) 1997-11-28
FI970425A (fi) 1997-03-21
JPH10504546A (ja) 1998-05-06
NO970429D0 (no) 1997-01-31
KR970704683A (ko) 1997-09-06
JP2960547B2 (ja) 1999-10-06
CZ31897A3 (en) 1997-07-16
CN1157608A (zh) 1997-08-20
NO970429L (no) 1997-04-03
EP0775111A1 (de) 1997-05-28
NZ288880A (en) 1999-03-29
AU2824495A (en) 1996-03-04
US5648091A (en) 1997-07-15
ATE204858T1 (de) 2001-09-15
CN1072646C (zh) 2001-10-10
CA2196295A1 (en) 1996-02-15

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