DE69519666D1 - Durch einen pyridinring substituierte thiazolidine und oxazolidine und ihre anwendung als hypoglykämische mittel - Google Patents

Durch einen pyridinring substituierte thiazolidine und oxazolidine und ihre anwendung als hypoglykämische mittel

Info

Publication number
DE69519666D1
DE69519666D1 DE69519666T DE69519666T DE69519666D1 DE 69519666 D1 DE69519666 D1 DE 69519666D1 DE 69519666 T DE69519666 T DE 69519666T DE 69519666 T DE69519666 T DE 69519666T DE 69519666 D1 DE69519666 D1 DE 69519666D1
Authority
DE
Germany
Prior art keywords
group
alkyl
cycloalkyl
substituted
oxazolidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69519666T
Other languages
English (en)
Other versions
DE69519666T2 (de
Inventor
Yoshio Ohara
Mikio Suzuki
Nobuhide Miyachi
Katsuhiro Kato
Keisuke Ohdoi
Tetsuya Kobayashi
Ken-Ichi Shikada
Takeshi Naito
Takashi Yotsumoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Original Assignee
Nissan Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp filed Critical Nissan Chemical Corp
Publication of DE69519666D1 publication Critical patent/DE69519666D1/de
Application granted granted Critical
Publication of DE69519666T2 publication Critical patent/DE69519666T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69519666T 1994-03-28 1995-03-27 Durch einen pyridinring substituierte thiazolidine und oxazolidine und ihre anwendung als hypoglykämische mittel Expired - Fee Related DE69519666T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5719294 1994-03-28
JP29517794 1994-11-29
PCT/JP1995/000560 WO1995026347A1 (en) 1994-03-28 1995-03-27 Thiazolidines and oxazolidines substituted by a pyridine ring and their use as hypoglycemic agents

Publications (2)

Publication Number Publication Date
DE69519666D1 true DE69519666D1 (de) 2001-01-25
DE69519666T2 DE69519666T2 (de) 2001-04-26

Family

ID=26398213

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69519666T Expired - Fee Related DE69519666T2 (de) 1994-03-28 1995-03-27 Durch einen pyridinring substituierte thiazolidine und oxazolidine und ihre anwendung als hypoglykämische mittel

Country Status (19)

Country Link
EP (1) EP0751944B1 (de)
KR (1) KR100340615B1 (de)
CN (1) CN1045776C (de)
AT (1) ATE198200T1 (de)
AU (1) AU683739B2 (de)
CA (1) CA2186381A1 (de)
CZ (1) CZ282096A3 (de)
DE (1) DE69519666T2 (de)
DK (1) DK0751944T3 (de)
ES (1) ES2154727T3 (de)
GR (1) GR3035277T3 (de)
HU (1) HUT76062A (de)
IL (1) IL113112A (de)
MX (1) MX9604430A (de)
NZ (1) NZ282893A (de)
PT (1) PT751944E (de)
RU (1) RU2125053C1 (de)
TW (1) TW420669B (de)
WO (1) WO1995026347A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69511683T2 (de) * 1994-03-08 2000-03-02 American Home Prod Thiazolidine-dion-derivate als antihyperglykemische mittel
ZA973850B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5919782A (en) * 1996-05-06 1999-07-06 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
ZA973848B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5985884A (en) * 1996-07-01 1999-11-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
US6114526A (en) 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6313113B1 (en) * 1997-04-15 2001-11-06 Reddy-Cheminor, Inc. Heterocyclic compounds having antidiabetic, hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US6011031A (en) * 1997-05-30 2000-01-04 Dr. Reddy's Research Foundation Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
US6756360B1 (en) 1998-12-24 2004-06-29 Metabasis Therapeutics, Inc. Combination of FBPase inhibitors and insulin sensitizers for the treatment of diabetes
NZ525164A (en) 2000-11-27 2005-04-29 Pfizer Prod Inc EP4 receptor selective agonists in the treatment of osteoporosis
ES2536547T3 (es) * 2006-03-24 2015-05-26 Array Biopharma, Inc. Análogos de 2-aminopiridina como activadores de glucoquinasa
CN101311167B (zh) * 2007-05-25 2011-04-06 天津药物研究院 1-苯基咪唑烷-2,4-二酮类衍生物及其用途
CN102884062B (zh) 2009-12-23 2016-08-03 嘉世高制药公司 氨基嘧啶激酶抑制剂
US8901145B2 (en) 2011-04-22 2014-12-02 Jasco Pharmaceuticals, LLC Aminopyrimidine kinase inhibitors
KR101990605B1 (ko) * 2011-11-04 2019-06-18 자스코 파머수티컬스, 엘엘씨 아미노피리미딘 키나아제 억제제
KR20160004272U (ko) 2015-06-04 2016-12-14 심명보 걸이구가 구비된 케이블행거
KR200488728Y1 (ko) 2017-06-15 2019-03-11 심명보 걸이구가 구비된 케이블행거
CN111065392A (zh) 2017-07-28 2020-04-24 应用治疗公司 用于治疗半乳糖血症的组合物和方法
KR102433164B1 (ko) * 2020-06-29 2022-08-18 한국전력공사 길이와 각도 조절이 가능한 케이블 행거

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5564586A (en) * 1978-11-09 1980-05-15 Takeda Chem Ind Ltd Thiazolidine derivative
US5061717A (en) * 1988-03-08 1991-10-29 Pfizer Inc. Thiazolidinedione hypoglycemic agents
MX15171A (es) * 1988-03-08 1993-05-01 Pfizer Derivados de tiazolidinodiona hipoglicemicos
JPH065228A (ja) * 1992-06-18 1994-01-14 Mitsubishi Electric Corp 偏向デバイス
TW245716B (de) * 1992-12-28 1995-04-21 Takeda Pharm Industry Co
KR960002625A (ko) * 1994-06-17 1996-01-26 제임스 조셉 드롱 다층 레지스트의 플라즈마 에칭을 위한 방법 및 장치

Also Published As

Publication number Publication date
HU9602645D0 (en) 1996-11-28
RU2125053C1 (ru) 1999-01-20
ATE198200T1 (de) 2001-01-15
MX9604430A (es) 1997-12-31
NZ282893A (en) 1997-07-27
DE69519666T2 (de) 2001-04-26
CN1045776C (zh) 1999-10-20
ES2154727T3 (es) 2001-04-16
HUT76062A (en) 1997-06-30
KR970701716A (ko) 1997-04-12
DK0751944T3 (da) 2001-01-08
EP0751944A1 (de) 1997-01-08
IL113112A0 (en) 1995-06-29
TW420669B (en) 2001-02-01
EP0751944B1 (de) 2000-12-20
AU2083395A (en) 1995-10-17
KR100340615B1 (ko) 2002-10-18
CA2186381A1 (en) 1995-10-05
CN1144526A (zh) 1997-03-05
CZ282096A3 (en) 1997-03-12
IL113112A (en) 2000-06-01
WO1995026347A1 (en) 1995-10-05
GR3035277T3 (en) 2001-04-30
AU683739B2 (en) 1997-11-20
PT751944E (pt) 2001-03-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee