DE69519656T2 - Verfahren zur Gewinnung von procyanidolischen Oligomeren - Google Patents

Verfahren zur Gewinnung von procyanidolischen Oligomeren

Info

Publication number
DE69519656T2
DE69519656T2 DE69519656T DE69519656T DE69519656T2 DE 69519656 T2 DE69519656 T2 DE 69519656T2 DE 69519656 T DE69519656 T DE 69519656T DE 69519656 T DE69519656 T DE 69519656T DE 69519656 T2 DE69519656 T2 DE 69519656T2
Authority
DE
Germany
Prior art keywords
mixt
extn
production
procyanidolic oligomers
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69519656T
Other languages
English (en)
Other versions
DE69519656D1 (de
Inventor
Bruno Franc
Christian Hoff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Application granted granted Critical
Publication of DE69519656D1 publication Critical patent/DE69519656D1/de
Publication of DE69519656T2 publication Critical patent/DE69519656T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
    • C07D311/62—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2 with oxygen atoms directly attached in position 3, e.g. anthocyanidins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/40—Separation, e.g. from natural material; Purification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Extraction Or Liquid Replacement (AREA)
DE69519656T 1994-10-11 1995-10-09 Verfahren zur Gewinnung von procyanidolischen Oligomeren Expired - Fee Related DE69519656T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9412126A FR2725447B1 (fr) 1994-10-11 1994-10-11 Procede d'obtention d'oligomeres procyanidoliques

Publications (2)

Publication Number Publication Date
DE69519656D1 DE69519656D1 (de) 2001-01-25
DE69519656T2 true DE69519656T2 (de) 2001-07-05

Family

ID=9467754

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69519656T Expired - Fee Related DE69519656T2 (de) 1994-10-11 1995-10-09 Verfahren zur Gewinnung von procyanidolischen Oligomeren

Country Status (7)

Country Link
US (1) US5804192A (de)
EP (1) EP0707005B1 (de)
JP (1) JPH08176137A (de)
AT (1) ATE198198T1 (de)
CA (1) CA2160218A1 (de)
DE (1) DE69519656T2 (de)
FR (1) FR2725447B1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2749303B1 (fr) * 1996-05-30 1998-08-07 Berkem Sa Procede d'extraction de polyphenols catechiques a partir de potentilles extrait obtenu et son utilisation
FR2776184B1 (fr) * 1998-03-17 2000-06-23 Caster Composition cosmetique capillaire anti-chute
KR100478296B1 (ko) 1999-04-23 2005-03-25 닛카우위스키가부시키가이샤 프로안토시아니딘 올리고머의 정제 방법
US7175862B2 (en) * 2004-01-28 2007-02-13 Access Business Group International Llc Method of preparing kakadu plum powder

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR968589A (fr) 1950-11-21 1950-11-30 Le leucoanthocyane de l'arachide et son procédé d'extraction
FR1036922A (fr) 1951-05-09 1953-09-14 Procédé d'extraction du leucocyanidol
GB884184A (en) * 1957-09-12 1961-12-06 Forestal Land Timber And Railw Improvements in or relating to the production of new compounds from wood
FR1427100A (fr) * 1964-12-14 1966-02-04 Ile De Rech Pharma Et Therapeu Procédé pour l'obtention d'hydroxyflavanne-3-4-diols
FR2092743A1 (en) * 1970-06-15 1972-01-28 Aquitaine Invest Pharma Complete extraction of total flavanol gomers from plats -peripheral - venous activity
FR2218109A1 (en) * 1973-02-16 1974-09-13 Oberlin Lab Extraction of leucocyanidol - from plants using methyl-ethyl ketone as selective solvent
GB1541469A (en) * 1976-12-01 1979-02-28 Inverni Della Beffa Spa Method of obtaining flavonolic oligomers
CH626359A5 (en) * 1978-01-01 1981-11-13 Inverni Della Beffa Spa Process for extracting flavanol oligomers
IT1219732B (it) * 1988-06-28 1990-05-24 Tecnofarmaci Spa Frazioni oligomeriche procianidoliche,loro procedimento di preparazione e composizioni farmaceutiche che le contengono

Also Published As

Publication number Publication date
ATE198198T1 (de) 2001-01-15
JPH08176137A (ja) 1996-07-09
EP0707005B1 (de) 2000-12-20
FR2725447B1 (fr) 1996-12-27
DE69519656D1 (de) 2001-01-25
CA2160218A1 (en) 1996-04-12
FR2725447A1 (fr) 1996-04-12
US5804192A (en) 1998-09-08
EP0707005A1 (de) 1996-04-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee