DE60216762D1 - Verfahren zur herstellung von allicin - Google Patents

Verfahren zur herstellung von allicin

Info

Publication number
DE60216762D1
DE60216762D1 DE60216762T DE60216762T DE60216762D1 DE 60216762 D1 DE60216762 D1 DE 60216762D1 DE 60216762 T DE60216762 T DE 60216762T DE 60216762 T DE60216762 T DE 60216762T DE 60216762 D1 DE60216762 D1 DE 60216762D1
Authority
DE
Germany
Prior art keywords
alliinase
allicin
source
alliin
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60216762T
Other languages
English (en)
Other versions
DE60216762T2 (de
Inventor
David Michael Williams
Mohen Pant
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neem Biotech Ltd
Original Assignee
Neem Biotech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neem Biotech Ltd filed Critical Neem Biotech Ltd
Application granted granted Critical
Publication of DE60216762D1 publication Critical patent/DE60216762D1/de
Publication of DE60216762T2 publication Critical patent/DE60216762T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y404/00—Carbon-sulfur lyases (4.4)
    • C12Y404/01—Carbon-sulfur lyases (4.4.1)
    • C12Y404/01004—Alliin lyase (4.4.1.4)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/10—Natural spices, flavouring agents or condiments; Extracts thereof
    • A23L27/105—Natural spices, flavouring agents or condiments; Extracts thereof obtained from liliaceae, e.g. onions, garlic
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/10—Natural spices, flavouring agents or condiments; Extracts thereof
    • A23L27/11—Natural spices, flavouring agents or condiments; Extracts thereof obtained by solvent extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Fruits And Vegetables (AREA)
DE60216762T 2001-07-04 2002-07-04 Verfahren zur herstellung von allicin Expired - Lifetime DE60216762T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0116361A GB2377219A (en) 2001-07-04 2001-07-04 Preparation of allicin
GB0116361 2001-07-04
PCT/GB2002/003083 WO2003004668A1 (en) 2001-07-04 2002-07-04 Process for the production of allicin

Publications (2)

Publication Number Publication Date
DE60216762D1 true DE60216762D1 (de) 2007-01-25
DE60216762T2 DE60216762T2 (de) 2007-11-15

Family

ID=9917934

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60216762T Expired - Lifetime DE60216762T2 (de) 2001-07-04 2002-07-04 Verfahren zur herstellung von allicin

Country Status (7)

Country Link
US (1) US7179632B2 (de)
EP (1) EP1404853B1 (de)
AT (1) ATE348185T1 (de)
DE (1) DE60216762T2 (de)
GB (1) GB2377219A (de)
WO (1) WO2003004668A1 (de)
ZA (1) ZA200400885B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108486181A (zh) * 2018-01-19 2018-09-04 新疆埃乐欣药业有限公司 高纯度大蒜辣素及其制备方法

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0903869D0 (en) * 2009-03-05 2009-04-22 Neem Biotech Ltd Process for the preparation of ajoene
CN102058527B (zh) * 2010-06-22 2012-05-23 新疆埃乐欣药业有限公司 一种抗肿瘤及抗感染的大蒜辣素注射液的制备方法及其低温连续搅拌超滤装置
US20120282334A1 (en) * 2011-05-02 2012-11-08 Korea Food Research Institute Process for preparing ajoene from garlic
CN103483231B (zh) * 2013-09-17 2015-07-08 暨南大学 一种具有光学活性的蒜氨酸的合成方法及其反应装置
CN104490766B (zh) * 2014-11-08 2017-09-22 新疆埃乐欣药业有限公司 大蒜辣素溶液及其生产方法
CN104498351B (zh) * 2014-11-08 2017-05-03 新疆埃乐欣药业有限公司 低温隔绝空气大蒜辣素生产装置及其使用方法
US10357314B2 (en) 2015-07-08 2019-07-23 Stryker European Holdings I, Llc Instrumentation and method for repair of a bone fracture
WO2018220338A1 (en) 2017-06-01 2018-12-06 Mootral Sa Animal feed supplement
CN111285788B (zh) * 2018-12-07 2022-10-14 武汉远大弘元股份有限公司 一种蒜氨酸的制备方法
CN109868181A (zh) * 2019-03-01 2019-06-11 临泉县清华地产中药材有限责任公司 一种大蒜油及其分离提纯方法
CN113924287A (zh) * 2019-05-29 2022-01-11 澳大利亚大蒜生产商私人有限公司 来自大蒜绿色顶部的保健品
US20220256890A1 (en) 2019-07-10 2022-08-18 Mootral Innovations Limited Animal feed supplement and animal feed composition
CN110615748B (zh) * 2019-10-15 2022-03-22 兰州大学 一种蒜氨酸提取工艺优化方法
US20240057638A1 (en) 2020-12-21 2024-02-22 Mootral Innovations Limited Compositions for reducing methane emission, methods for improving the metabolic efficiency of ruminant animals and methanogenesis inhibitor administration
CN114836485B (zh) * 2022-04-19 2023-12-05 齐鲁工业大学 从蒜中提取分离阿霍烯的方法
CN116162049A (zh) * 2023-02-21 2023-05-26 石河子大学 一种二烯丙基三硫醚及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19500863A1 (de) * 1995-01-13 1996-07-18 Consortium Elektrochem Ind Verfahren zur Herstellung von Ajoen
IL117934A0 (en) * 1996-04-16 1996-08-04 Yeda Res & Dev Continuous production of allicin
US5788758A (en) * 1996-06-17 1998-08-04 House Foods Corporation Method for manufacturing blue pigment

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108486181A (zh) * 2018-01-19 2018-09-04 新疆埃乐欣药业有限公司 高纯度大蒜辣素及其制备方法
CN108486181B (zh) * 2018-01-19 2021-09-10 新疆埃乐欣药业有限公司 高纯度大蒜辣素及其制备方法

Also Published As

Publication number Publication date
DE60216762T2 (de) 2007-11-15
GB0116361D0 (en) 2001-08-29
US20040247711A1 (en) 2004-12-09
WO2003004668A1 (en) 2003-01-16
EP1404853B1 (de) 2006-12-13
ATE348185T1 (de) 2007-01-15
ZA200400885B (en) 2005-04-26
US7179632B2 (en) 2007-02-20
GB2377219A (en) 2003-01-08
EP1404853A1 (de) 2004-04-07

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