DE69519033D1 - Zielspezifische screens und ihre verwendung zur ermittelung von kleinen organischen molekularen pharmakophoren - Google Patents

Zielspezifische screens und ihre verwendung zur ermittelung von kleinen organischen molekularen pharmakophoren

Info

Publication number
DE69519033D1
DE69519033D1 DE69519033T DE69519033T DE69519033D1 DE 69519033 D1 DE69519033 D1 DE 69519033D1 DE 69519033 T DE69519033 T DE 69519033T DE 69519033 T DE69519033 T DE 69519033T DE 69519033 D1 DE69519033 D1 DE 69519033D1
Authority
DE
Germany
Prior art keywords
small organic
antibodies
pharmacophors
target
parts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69519033T
Other languages
English (en)
Other versions
DE69519033T2 (de
Inventor
J Blume
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DGI BioTechnologies LLC
Original Assignee
DGI BioTechnologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DGI BioTechnologies LLC filed Critical DGI BioTechnologies LLC
Application granted granted Critical
Publication of DE69519033D1 publication Critical patent/DE69519033D1/de
Publication of DE69519033T2 publication Critical patent/DE69519033T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2869—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against hormone receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854—Immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69519033T 1994-08-03 1995-08-02 Zielspezifische screens und ihre verwendung zur ermittelung von kleinen organischen molekularen pharmakophoren Expired - Fee Related DE69519033T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28608494A 1994-08-03 1994-08-03
US08/473,105 US6010861A (en) 1994-08-03 1995-06-07 Target specific screens and their use for discovering small organic molecular pharmacophores
PCT/US1995/010182 WO1996004557A2 (en) 1994-08-03 1995-08-02 Target specific screens and their use for discovering small organic molecular pharmacophores

Publications (2)

Publication Number Publication Date
DE69519033D1 true DE69519033D1 (de) 2000-11-09
DE69519033T2 DE69519033T2 (de) 2001-05-17

Family

ID=26963579

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69519033T Expired - Fee Related DE69519033T2 (de) 1994-08-03 1995-08-02 Zielspezifische screens und ihre verwendung zur ermittelung von kleinen organischen molekularen pharmakophoren

Country Status (8)

Country Link
US (3) US6010861A (de)
EP (2) EP0774118B1 (de)
JP (1) JPH10507517A (de)
AT (1) ATE196802T1 (de)
AU (1) AU3363195A (de)
CA (1) CA2196679A1 (de)
DE (1) DE69519033T2 (de)
WO (1) WO1996004557A2 (de)

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Also Published As

Publication number Publication date
US20030092057A1 (en) 2003-05-15
JPH10507517A (ja) 1998-07-21
EP0774118A2 (de) 1997-05-21
US6010861A (en) 2000-01-04
ATE196802T1 (de) 2000-10-15
WO1996004557A3 (en) 1996-04-25
EP0774118B1 (de) 2000-10-04
CA2196679A1 (en) 1996-02-15
US20040072271A1 (en) 2004-04-15
WO1996004557A2 (en) 1996-02-15
AU3363195A (en) 1996-03-04
EP1028315A2 (de) 2000-08-16
DE69519033T2 (de) 2001-05-17
EP1028315A3 (de) 2004-01-02

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