AU3439589A - Molecular sticks for controlling protein conformation - Google Patents

Molecular sticks for controlling protein conformation

Info

Publication number
AU3439589A
AU3439589A AU34395/89A AU3439589A AU3439589A AU 3439589 A AU3439589 A AU 3439589A AU 34395/89 A AU34395/89 A AU 34395/89A AU 3439589 A AU3439589 A AU 3439589A AU 3439589 A AU3439589 A AU 3439589A
Authority
AU
Australia
Prior art keywords
protein conformation
controlling protein
sticks
molecular
molecular sticks
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU34395/89A
Inventor
Lawrence M. Kauvar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TERRAPIN DIAGNOSTICS Inc
Original Assignee
TERRAPIN DIAGNOSTICS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TERRAPIN DIAGNOSTICS Inc filed Critical TERRAPIN DIAGNOSTICS Inc
Publication of AU3439589A publication Critical patent/AU3439589A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/06—Peptides being immobilised on, or in, an organic carrier attached to the carrier via a bridging agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
AU34395/89A 1988-03-24 1989-03-23 Molecular sticks for controlling protein conformation Abandoned AU3439589A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17262388A 1988-03-24 1988-03-24
US172623 1993-12-22

Publications (1)

Publication Number Publication Date
AU3439589A true AU3439589A (en) 1989-10-16

Family

ID=22628489

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34395/89A Abandoned AU3439589A (en) 1988-03-24 1989-03-23 Molecular sticks for controlling protein conformation

Country Status (2)

Country Link
AU (1) AU3439589A (en)
WO (1) WO1989009233A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541116A (en) * 1991-09-30 1996-07-30 B.R.A.H.M.S. Diagnostica Gmbh Method for the stabilization of endogenous, physiologically active peptides
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores
US7192713B1 (en) 1999-05-18 2007-03-20 President And Fellows Of Harvard College Stabilized compounds having secondary structure motifs
CN105061577A (en) 2006-12-14 2015-11-18 爱勒让治疗公司 Bis-sulfhydryl macrocyclization systems
US7981998B2 (en) 2006-12-14 2011-07-19 Aileron Therapeutics, Inc. Bis-sulfhydryl macrocyclization systems
EP2952522B1 (en) 2007-01-31 2019-10-30 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
AU2008218116B2 (en) 2007-02-23 2012-04-05 Aileron Therapeutics, Inc. Triazole macrocycle systems
US8592377B2 (en) 2007-03-28 2013-11-26 President And Fellows Of Harvard College Stitched polypeptides
AU2010204648B2 (en) 2009-01-14 2016-09-01 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
AU2010298338A1 (en) 2009-09-22 2012-04-12 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
KR20170058446A (en) 2010-08-13 2017-05-26 에일러론 테라퓨틱스 인코포레이티드 Peptidomimetic macrocycles
KR20140100937A (en) 2011-10-18 2014-08-18 에일러론 테라퓨틱스 인코포레이티드 Peptidomimetic macrocycles
CN108912211A (en) 2012-02-15 2018-11-30 爱勒让治疗公司 Triazole crosslinking and thioether crosslinking peptidomimetic macrocyclic compound
CA2862038C (en) 2012-02-15 2021-05-25 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
CN104812384B (en) 2012-11-01 2020-09-18 爱勒让治疗公司 Disubstituted amino acids and methods of making and using the same
AU2015320549A1 (en) 2014-09-24 2017-04-13 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
SG10201902598VA (en) 2014-09-24 2019-04-29 Aileron Therapeutics Inc Peptidomimetic macrocycles and formulations thereof
BR112017019738A2 (en) 2015-03-20 2018-05-29 Aileron Therapeutics Inc peptidomimetic macrocycles and their uses
WO2017004548A1 (en) 2015-07-01 2017-01-05 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
CN108368161A (en) 2015-09-10 2018-08-03 艾瑞朗医疗公司 Peptidomimetic macrocyclic compound as MCL-1 conditioning agents

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4716116A (en) * 1980-12-04 1987-12-29 Owens-Illinois Glass Container Inc. Protein modification to provide enzyme activity
JPS6115899A (en) * 1984-06-29 1986-01-23 Sumitomo Chem Co Ltd Difunctional ligand compound and conjugated protein

Also Published As

Publication number Publication date
WO1989009233A1 (en) 1989-10-05

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