DE69509182D1 - Herstellung N-9-substituierter Guanin-Verbindungen - Google Patents
Herstellung N-9-substituierter Guanin-VerbindungenInfo
- Publication number
- DE69509182D1 DE69509182D1 DE69509182T DE69509182T DE69509182D1 DE 69509182 D1 DE69509182 D1 DE 69509182D1 DE 69509182 T DE69509182 T DE 69509182T DE 69509182 T DE69509182 T DE 69509182T DE 69509182 D1 DE69509182 D1 DE 69509182D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- substituted guanine
- guanine compounds
- compounds
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/286,045 US5565565A (en) | 1994-08-04 | 1994-08-04 | Preparation of N-9 substituted guanine compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69509182D1 true DE69509182D1 (de) | 1999-05-27 |
DE69509182T2 DE69509182T2 (de) | 1999-10-21 |
Family
ID=23096824
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69509182T Expired - Lifetime DE69509182T2 (de) | 1994-08-04 | 1995-07-21 | Herstellung N-9-substituierter Guanin-Verbindungen |
Country Status (9)
Country | Link |
---|---|
US (1) | US5565565A (de) |
EP (1) | EP0704445B1 (de) |
JP (1) | JP2944474B2 (de) |
KR (1) | KR100218610B1 (de) |
CN (2) | CN1051084C (de) |
AT (1) | ATE179174T1 (de) |
DE (1) | DE69509182T2 (de) |
DK (1) | DK0704445T3 (de) |
ES (1) | ES2131730T3 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997024357A1 (en) * | 1995-12-28 | 1997-07-10 | Mallinckrodt Chemical, Inc. | Process for synthesis and purification of a compound useful in the preparation of acyclovir |
US6040446A (en) * | 1996-01-26 | 2000-03-21 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative |
EP0806425B1 (de) * | 1996-04-09 | 2001-08-29 | Lupin Laboratories Limited | Verbessertes regiospezifisches Verfahren zur Herstellung von azyklische Nucleosiden |
JPH11192744A (ja) | 1997-12-29 | 1999-07-21 | Canon Inc | Ledアレイ駆動装置および方法 |
CN1091445C (zh) * | 1999-12-29 | 2002-09-25 | 湖北省医药工业研究院 | 抗病毒药物中间体、它们的制备及应用 |
WO2003033498A2 (en) * | 2001-10-15 | 2003-04-24 | Ranbaxy Laboratories Limited | A process for the treatment of ganciclovir intermediate n2-acetyl-9-(1, 3-diacetoxy-2-propoxymethyl) guanine |
WO2004048380A1 (en) * | 2002-11-22 | 2004-06-10 | Ranbaxy Laboratories Limited | Process for the synthesis of ganciclovir |
ZA200702234B (en) * | 2006-03-21 | 2008-07-30 | Cipla Ltd | Preparation of ester of purine derivatives |
US7497521B2 (en) * | 2006-08-30 | 2009-03-03 | Honda Motor Co., Ltd | Seat belt retractor mounting system |
CA2691430C (en) | 2007-06-28 | 2013-01-08 | Spinal Elements, Inc. | Spinal stabilization device |
AU2008293734A1 (en) * | 2007-08-24 | 2009-03-05 | Spinal Elements, Inc. | Loop rod spinal stabilization device |
CN108503668A (zh) * | 2018-05-11 | 2018-09-07 | 浙江华贝药业有限责任公司 | 一种三甲基苯氧基硅烷的合成方法 |
CN114047262A (zh) * | 2021-10-14 | 2022-02-15 | 湖北省宏源药业科技股份有限公司 | 一种分离测定易水解大极性化合物的方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1523865A (en) * | 1974-09-02 | 1978-09-06 | Wellcome Found | Purine compunds and salts thereof |
US4355032B2 (en) * | 1981-05-21 | 1990-10-30 | 9-(1,3-dihydroxy-2-propoxymethyl)guanine as antiviral agent | |
AU569462B2 (en) * | 1981-08-11 | 1988-02-04 | Wellcome Foundation Limited, The | Antiviral purine derivatives |
NZ201662A (en) * | 1981-08-26 | 1986-07-11 | Merck & Co Inc | 9-(1,3-(and 2,3)-dihydroxy-1-(and 2)-propoxy-methyl)guanine derivatives and methods for their preparation |
US5250535A (en) * | 1982-02-01 | 1993-10-05 | Syntex Inc. | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent |
US4621140A (en) * | 1984-02-23 | 1986-11-04 | Syntex (U.S.A.) Inc. | Process for preparing 2,6-substituted-9-(1,3-dihydroxy-2-propoxymethyl)-purines and certain derivatives |
DE3627024A1 (de) * | 1985-09-24 | 1987-04-02 | Hoechst Ag | In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine |
DE3631562A1 (de) * | 1986-09-17 | 1988-03-31 | Hoechst Ag | In 9-stellung substituierte 2-amino-6-alkoxy-purine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine |
JPS63107982A (ja) * | 1986-10-27 | 1988-05-12 | Minofuaagen Seiyaku Honpo:Goushi | 9−〔(2−ハイドロキシエトキシ)メチル〕−グアニンの製造方法 |
JP3225545B2 (ja) * | 1991-09-18 | 2001-11-05 | 味の素株式会社 | 非環状ヌクレオシド類の製造法 |
JPH05213903A (ja) * | 1991-12-09 | 1993-08-24 | Mitsubishi Kasei Corp | アシクロヌクレオシド誘導体の製造方法 |
-
1994
- 1994-08-04 US US08/286,045 patent/US5565565A/en not_active Expired - Lifetime
-
1995
- 1995-07-21 ES ES95111473T patent/ES2131730T3/es not_active Expired - Lifetime
- 1995-07-21 DE DE69509182T patent/DE69509182T2/de not_active Expired - Lifetime
- 1995-07-21 AT AT95111473T patent/ATE179174T1/de active
- 1995-07-21 DK DK95111473T patent/DK0704445T3/da active
- 1995-07-21 EP EP95111473A patent/EP0704445B1/de not_active Expired - Lifetime
- 1995-08-03 CN CN95108673A patent/CN1051084C/zh not_active Expired - Lifetime
- 1995-08-03 KR KR1019950023927A patent/KR100218610B1/ko not_active IP Right Cessation
- 1995-08-03 JP JP7197844A patent/JP2944474B2/ja not_active Expired - Lifetime
-
1999
- 1999-06-30 CN CNB991089235A patent/CN1137892C/zh not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK0704445T3 (da) | 1999-10-25 |
ATE179174T1 (de) | 1999-05-15 |
DE69509182T2 (de) | 1999-10-21 |
ES2131730T3 (es) | 1999-08-01 |
US5565565A (en) | 1996-10-15 |
EP0704445A1 (de) | 1996-04-03 |
CN1051084C (zh) | 2000-04-05 |
EP0704445B1 (de) | 1999-04-21 |
JPH0859662A (ja) | 1996-03-05 |
CN1137892C (zh) | 2004-02-11 |
JP2944474B2 (ja) | 1999-09-06 |
KR100218610B1 (ko) | 1999-09-01 |
CN1120044A (zh) | 1996-04-10 |
CN1246477A (zh) | 2000-03-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |