DE69434211D1 - Phenylacetate und derivate, allein oder in kombination mit anderen verbindungen, zur behandlung von neoplastischen und anderen erkrankungen - Google Patents

Phenylacetate und derivate, allein oder in kombination mit anderen verbindungen, zur behandlung von neoplastischen und anderen erkrankungen

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Publication number
DE69434211D1
DE69434211D1 DE69434211T DE69434211T DE69434211D1 DE 69434211 D1 DE69434211 D1 DE 69434211D1 DE 69434211 T DE69434211 T DE 69434211T DE 69434211 T DE69434211 T DE 69434211T DE 69434211 D1 DE69434211 D1 DE 69434211D1
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Germany
Prior art keywords
phenylacetate
methods
derivatives
alone
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69434211T
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English (en)
Other versions
DE69434211T2 (de
Inventor
Dvorit Samid
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
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US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/135,661 external-priority patent/US5635532A/en
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Application granted granted Critical
Publication of DE69434211D1 publication Critical patent/DE69434211D1/de
Publication of DE69434211T2 publication Critical patent/DE69434211T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
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    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
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    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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DE69434211T 1993-10-12 1994-10-12 Phenylacetate und derivate, allein oder in kombination mit anderen verbindungen, zur behandlung von neoplastischen und anderen erkrankungen Expired - Lifetime DE69434211T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/135,661 US5635532A (en) 1991-10-21 1993-10-12 Compositions and methods for therapy and prevention of pathologies including cancer, AIDS and anemia
US135661 1993-10-12
US207521 1994-03-07
US08/207,521 US5605930A (en) 1991-10-21 1994-03-07 Compositions and methods for treating and preventing pathologies including cancer
PCT/US1994/011492 WO1995010271A2 (en) 1993-10-12 1994-10-12 Phenylacetate and derivatives alone or in combination with other compounds against neoplastic conditions and other disorders

Publications (2)

Publication Number Publication Date
DE69434211D1 true DE69434211D1 (de) 2005-02-03
DE69434211T2 DE69434211T2 (de) 2005-12-15

Family

ID=26833540

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69434211T Expired - Lifetime DE69434211T2 (de) 1993-10-12 1994-10-12 Phenylacetate und derivate, allein oder in kombination mit anderen verbindungen, zur behandlung von neoplastischen und anderen erkrankungen
DE69435086T Expired - Lifetime DE69435086T2 (de) 1993-10-12 1994-10-12 Phenylacetate und Derivate, allein oder in Kombination mit anderen Verbindungen, zur Behandlung von neoplastischen und anderen Erkrankungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69435086T Expired - Lifetime DE69435086T2 (de) 1993-10-12 1994-10-12 Phenylacetate und Derivate, allein oder in Kombination mit anderen Verbindungen, zur Behandlung von neoplastischen und anderen Erkrankungen

Country Status (15)

Country Link
US (4) US5605930A (de)
EP (2) EP1523982B1 (de)
JP (5) JP3628694B2 (de)
AT (2) ATE285760T1 (de)
AU (1) AU702051B2 (de)
CA (1) CA2173976C (de)
DE (2) DE69434211T2 (de)
DK (1) DK1523982T3 (de)
ES (2) ES2233931T3 (de)
HK (1) HK1077204A1 (de)
IL (1) IL111251A (de)
NZ (1) NZ275673A (de)
PT (2) PT725635E (de)
SI (1) SI1523982T1 (de)
WO (1) WO1995010271A2 (de)

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