ATE120447T1 - Polyamin-derivate als antineoplastische mittel. - Google Patents
Polyamin-derivate als antineoplastische mittel.Info
- Publication number
- ATE120447T1 ATE120447T1 AT90100303T AT90100303T ATE120447T1 AT E120447 T1 ATE120447 T1 AT E120447T1 AT 90100303 T AT90100303 T AT 90100303T AT 90100303 T AT90100303 T AT 90100303T AT E120447 T1 ATE120447 T1 AT E120447T1
- Authority
- AT
- Austria
- Prior art keywords
- antineoplastic agents
- polyamine derivatives
- compounds
- formula
- polyamine
- Prior art date
Links
- 229940034982 antineoplastic agent Drugs 0.000 title 1
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 229920000768 polyamine Polymers 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 229940100534 Polyamine oxidase inhibitor Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/09—Diamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/14—Amines containing amino groups bound to at least two aminoalkyl groups, e.g. diethylenetriamines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29561789A | 1989-01-10 | 1989-01-10 | |
| US29572189A | 1989-01-10 | 1989-01-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE120447T1 true ATE120447T1 (de) | 1995-04-15 |
Family
ID=26969226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90100303T ATE120447T1 (de) | 1989-01-10 | 1990-01-08 | Polyamin-derivate als antineoplastische mittel. |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0378146B1 (de) |
| AT (1) | ATE120447T1 (de) |
| DE (1) | DE69018099T2 (de) |
| DK (1) | DK0378146T3 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5109024A (en) * | 1987-02-03 | 1992-04-28 | Merrell Dow Pharmaceuticals Inc. | Polyamine derivatives as antineoplastic agents |
| US5719193A (en) * | 1989-05-23 | 1998-02-17 | Merrell Pharmaceuticals, Inc. | Method of potentiating cell-mediated immunity utilizing polyamine derivatives |
| US5561136A (en) * | 1990-12-13 | 1996-10-01 | Merrell Pharmaceuticals Inc. | Method of treating cancer by conjunctive therapy with N,N'-bis[ethylamino)propyl]-1,7-heptanediamine and a cytotoxic agent |
| AU648846B2 (en) * | 1990-12-13 | 1994-05-05 | Merrell Dow Pharmaceuticals Inc. | Method of treating cancer by conjunctive therapy with N,N-bis(3-(ethylamino)propyl)-1,7-heptanediamine and a cytotoxic agent |
| GB9105489D0 (en) * | 1991-03-15 | 1991-05-01 | Johnson Matthey Plc | Improvements in chemical compounds |
| NZ262986A (en) * | 1993-02-23 | 1997-06-24 | Merrell Dow Pharma | Polyamine derivatives; use in protecting mammalian cells from the deleterious effects of ionising radiation and/or mutagenic chemicals |
| MXPA00009705A (es) * | 1998-04-03 | 2003-07-14 | Univ Manitoba | Uso de poliaminas en el tratamiento de sintomas dermatologicos. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1305425C (en) * | 1986-12-02 | 1992-07-21 | Raymond J. Bergeron | Anti-neoplastic spermine derivative |
| AU602186B2 (en) * | 1987-02-03 | 1990-10-04 | Merrell Dow Pharmaceuticals Inc. | Novel polyamine derivatives |
| ZA887410B (en) * | 1987-10-08 | 1989-06-28 | Merrell Dow Pharma | Polyamine derivatives as antineoplastic agents |
-
1990
- 1990-01-08 AT AT90100303T patent/ATE120447T1/de not_active IP Right Cessation
- 1990-01-08 EP EP90100303A patent/EP0378146B1/de not_active Expired - Lifetime
- 1990-01-08 DK DK90100303.8T patent/DK0378146T3/da active
- 1990-01-08 DE DE69018099T patent/DE69018099T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK0378146T3 (da) | 1995-05-01 |
| DE69018099D1 (de) | 1995-05-04 |
| EP0378146A3 (de) | 1991-04-24 |
| DE69018099T2 (de) | 1995-08-03 |
| EP0378146B1 (de) | 1995-03-29 |
| EP0378146A2 (de) | 1990-07-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEFA | Change of the company name | ||
| REN | Ceased due to non-payment of the annual fee |