DE69434196D1 - Eingefügter promoter enthaltendes rekombinantes milchsäure bakterium - Google Patents

Eingefügter promoter enthaltendes rekombinantes milchsäure bakterium

Info

Publication number
DE69434196D1
DE69434196D1 DE69434196T DE69434196T DE69434196D1 DE 69434196 D1 DE69434196 D1 DE 69434196D1 DE 69434196 T DE69434196 T DE 69434196T DE 69434196 T DE69434196 T DE 69434196T DE 69434196 D1 DE69434196 D1 DE 69434196D1
Authority
DE
Germany
Prior art keywords
lactic acid
acid bacterium
promoter
recombinant
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69434196T
Other languages
English (en)
Other versions
DE69434196T2 (de
DE69434196T3 (de
Inventor
Hans Israelsen
Egon Bech Hansen
Eric Johansen
Soren Michael Madsen
Dan Nilsson
Astrid Vrang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chr Hansen AS
Bioneer AS
Original Assignee
Chr Hansen AS
Bioteknologisk Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26065017&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69434196(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DK921579A external-priority patent/DK157992D0/da
Priority claimed from DK98893A external-priority patent/DK98893D0/da
Application filed by Chr Hansen AS, Bioteknologisk Institut filed Critical Chr Hansen AS
Application granted granted Critical
Publication of DE69434196D1 publication Critical patent/DE69434196D1/de
Publication of DE69434196T2 publication Critical patent/DE69434196T2/de
Publication of DE69434196T3 publication Critical patent/DE69434196T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1051—Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69434196T 1992-12-30 1994-01-03 Einen eingefügten Promotor enthaltendes rekombinantes Milchsäure Bakterium Expired - Lifetime DE69434196T3 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DK157992 1992-12-30
DK921579A DK157992D0 (da) 1992-12-30 1992-12-30 Bakteriestamme
DK98893 1993-09-01
DK98893A DK98893D0 (da) 1993-09-01 1993-09-01 Bakteriestamme
PCT/DK1994/000004 WO1994016086A1 (en) 1992-12-30 1994-01-03 Recombinant lactic acid bacterium containing an inserted promoter and method of constructing same

Publications (3)

Publication Number Publication Date
DE69434196D1 true DE69434196D1 (de) 2005-01-27
DE69434196T2 DE69434196T2 (de) 2006-02-23
DE69434196T3 DE69434196T3 (de) 2010-09-23

Family

ID=26065017

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69434196T Expired - Lifetime DE69434196T3 (de) 1992-12-30 1994-01-03 Einen eingefügten Promotor enthaltendes rekombinantes Milchsäure Bakterium

Country Status (11)

Country Link
EP (1) EP0677110B2 (de)
JP (1) JP3553065B2 (de)
AT (1) ATE285476T1 (de)
AU (1) AU675821B2 (de)
CA (1) CA2152898C (de)
DE (1) DE69434196T3 (de)
DK (1) DK0677110T4 (de)
ES (1) ES2235159T5 (de)
NZ (2) NZ286635A (de)
PT (1) PT677110E (de)
WO (1) WO1994016086A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU757106B2 (en) * 1996-09-06 2003-02-06 Bioneer A/S Lactic acid bacterial regulatable expression system
PT925364E (pt) * 1996-09-06 2003-03-31 Bioteknologisk Inst Sistema de expressao regulavel de bacterias de acido lactico
BR9809197B1 (pt) 1997-05-30 2013-09-03 método de aumento da taxa de crescimento e/ou de controle da atividade metabólica de uma cepa bacteriana de ácido lático e composição de cultura de iniciador.
GB9718616D0 (en) * 1997-09-02 1997-11-05 Queen Mary & Westfield College Oral vaccine
FR2770536B1 (fr) * 1997-11-06 2001-09-21 Texel Nouveau plasmide non rcr apte a etre transfere dans des bact eries lactiques; utilisation comme outil de clonage et d'expression
US7358083B1 (en) 1998-04-21 2008-04-15 Chr. Hansen A/S Food-grade cloning vector and their use in lactic acid bacteria
CA2325664C (en) * 1998-04-21 2010-01-05 Chr. Hansen A/S Food-grade cloning vector and their use in lactic acid bacteria
ES2276691T3 (es) 1999-08-06 2007-07-01 Bioneer A/S Peptidos señales aislados de lactococcus lactis.
PT1356073E (pt) * 2000-10-20 2010-02-15 Bioneer As Método de fermentação aperfeiçoado para a produção de produtos genéticos heterólogos em bactérias do ácido láctico
ES2354775T5 (es) 2000-11-06 2021-12-23 Chr Hansen As Método de producción de quimosina no bovina y uso de la misma
ES2968836T3 (es) 2012-01-12 2024-05-14 Endo Global Ventures Enzima del clostridium histolyticum
CN105338819A (zh) 2013-06-27 2016-02-17 星巴克公司，贸易用名星巴克咖啡公司 用于饮料和其他食品的生物保存方法
WO2018062225A1 (ja) * 2016-09-28 2018-04-05 株式会社アネロファーマ・サイエンス ビフィドバクテリウム属細菌の遺伝子発現用プロモーター
KR101915949B1 (ko) * 2018-01-09 2018-11-07 주식회사 쎌바이오텍 유전자 발현 카세트 및 그를 포함하는 발현벡터

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8503316A (nl) * 1985-11-29 1987-06-16 Stichting Nl I Zuivelonderzoek Werkwijze voor het bereiden van proteinen met behulp van gastheer-organismen, in het bijzonder melkzuurbacterien, welke recombinant dna-plasmiden met een hoge replicon-aktiviteit en een hoge promotor-aktiviteit voor het betreffende proteine-coderende gen bevatten, de van dergelijke recombinant dna-plasmiden voorziene gastheerorganismen, de recombinant dna-plasmiden zelve, de replicon-aktiviteit en promotor-aktiviteit coderende dna-fragmenten, alsmede de verkregen proteinen.
NL8701378A (nl) * 1987-06-12 1989-01-02 Nl Zuivelonderzoek Inst Dna-fragmenten, omvattende een melkzuurbacterie-specifiek regulatorgebied voor het tot expressie brengen van voor normaliter heterologe eiwitten coderende genen, op dergelijke dna-fragmenten gebaseerde recombinant-plasmiden, microorganismen, in het bijzonder melkzuurbacterien, welke deze recombinant-plasmiden, bevatten alsmede de met behulp van voorstaande microorganismen bereide heterologe eiwitten resp. produkten.
NL8803004A (nl) * 1988-12-07 1990-07-02 Bcz Friesland Bv Genetisch gemanipuleerde melkzuurbacterien en hun gebruik in de bereiding van kaas, alsmede recombinante plasmiden.
WO1992004451A1 (en) * 1990-08-30 1992-03-19 Genesit Oy Promoter probe vectors, able to replicate in e.coli, b.subtilis, lactococci and lactobacillus as well as uses thereof

Also Published As

Publication number Publication date
EP0677110B1 (de) 2004-12-22
DE69434196T2 (de) 2006-02-23
PT677110E (pt) 2005-05-31
ES2235159T3 (es) 2005-07-01
WO1994016086A1 (en) 1994-07-21
AU5832594A (en) 1994-08-15
ATE285476T1 (de) 2005-01-15
AU675821B2 (en) 1997-02-20
DK0677110T3 (da) 2005-01-24
DE69434196T3 (de) 2010-09-23
EP0677110A1 (de) 1995-10-18
ES2235159T5 (es) 2010-05-11
EP0677110B2 (de) 2010-01-27
DK0677110T4 (da) 2010-05-25
CA2152898A1 (en) 1994-07-21
CA2152898C (en) 2003-04-29
NZ259510A (en) 1997-06-24
NZ286635A (en) 1997-06-24
JP3553065B2 (ja) 2004-08-11
JPH08500739A (ja) 1996-01-30

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: CHR. HANSEN A/S, HORSHOLM, DK

Owner name: BIONEER A/S, HOERSHOLM, DK

8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings