ATE285476T1 - Eingefügter promoter enthaltendes rekombinantes milchsäure bakterium - Google Patents

Eingefügter promoter enthaltendes rekombinantes milchsäure bakterium

Info

Publication number
ATE285476T1
ATE285476T1 AT94904150T AT94904150T ATE285476T1 AT E285476 T1 ATE285476 T1 AT E285476T1 AT 94904150 T AT94904150 T AT 94904150T AT 94904150 T AT94904150 T AT 94904150T AT E285476 T1 ATE285476 T1 AT E285476T1
Authority
AT
Austria
Prior art keywords
lactic acid
promoter
gene
recombinant
regulatable
Prior art date
Application number
AT94904150T
Other languages
English (en)
Inventor
Hans Israelsen
Egon Bech Hansen
Eric Johansen
Soren Michael Madsen
Dan Nilsson
Astrid Vrang
Original Assignee
Bioteknologisk Inst
Chr Hansen As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26065017&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE285476(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DK921579A external-priority patent/DK157992D0/da
Priority claimed from DK98893A external-priority patent/DK98893D0/da
Application filed by Bioteknologisk Inst, Chr Hansen As filed Critical Bioteknologisk Inst
Application granted granted Critical
Publication of ATE285476T1 publication Critical patent/ATE285476T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1051—Gene trapping, e.g. exon-, intron-, IRES-, signal sequence-trap cloning, trap vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Dairy Products (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
AT94904150T 1992-12-30 1994-01-03 Eingefügter promoter enthaltendes rekombinantes milchsäure bakterium ATE285476T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK921579A DK157992D0 (da) 1992-12-30 1992-12-30 Bakteriestamme
DK98893A DK98893D0 (da) 1993-09-01 1993-09-01 Bakteriestamme
PCT/DK1994/000004 WO1994016086A1 (en) 1992-12-30 1994-01-03 Recombinant lactic acid bacterium containing an inserted promoter and method of constructing same

Publications (1)

Publication Number Publication Date
ATE285476T1 true ATE285476T1 (de) 2005-01-15

Family

ID=26065017

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94904150T ATE285476T1 (de) 1992-12-30 1994-01-03 Eingefügter promoter enthaltendes rekombinantes milchsäure bakterium

Country Status (11)

Country Link
EP (1) EP0677110B2 (de)
JP (1) JP3553065B2 (de)
AT (1) ATE285476T1 (de)
AU (1) AU675821B2 (de)
CA (1) CA2152898C (de)
DE (1) DE69434196T3 (de)
DK (1) DK0677110T4 (de)
ES (1) ES2235159T5 (de)
NZ (2) NZ259510A (de)
PT (1) PT677110E (de)
WO (1) WO1994016086A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69716622T2 (de) * 1996-09-06 2003-07-10 Bioteknologisk Institut, Hoersholm Milchsäurebakterielles regulierbares expressionssystem
AU757106B2 (en) * 1996-09-06 2003-02-06 Bioneer A/S Lactic acid bacterial regulatable expression system
DK0985043T4 (en) 1997-05-30 2017-04-24 Chr Hansen As Lactic acid bacterial starter cultures and compositions thereof
GB9718616D0 (en) * 1997-09-02 1997-11-05 Queen Mary & Westfield College Oral vaccine
FR2770536B1 (fr) * 1997-11-06 2001-09-21 Texel Nouveau plasmide non rcr apte a etre transfere dans des bact eries lactiques; utilisation comme outil de clonage et d'expression
EP1073757B1 (de) * 1998-04-21 2012-11-28 Chr. Hansen A/S Nahrungmittel-taugliche klonierungsvektoren und deren verwendung in milchsäurebakterien
US7358083B1 (en) 1998-04-21 2008-04-15 Chr. Hansen A/S Food-grade cloning vector and their use in lactic acid bacteria
DK1206556T3 (da) * 1999-08-06 2007-05-21 Bioneer As Signalpeptider isoleret fra LACTOCOCCUS LACTIS
CA2426084C (en) * 2000-10-20 2013-12-10 Bioteknologisk Institut Improved fermentation method for production of heterologous gene products in lactic acid bacteria
EP1334182B2 (de) 2000-11-06 2021-03-24 Chr. Hansen A/S Verfahren zur herstellung von nicht aus dem rind stammendem chymosin und dessen anwendung
PT2802652T (pt) 2012-01-12 2019-09-10 Endo Global Ventures Enzimas de clostridium histolyticum
WO2014209912A1 (en) 2013-06-27 2014-12-31 Starbucks Corporation D/B/A Starbucks Coffee Company Biopreservation methods for beverages and other foods
JPWO2018062225A1 (ja) * 2016-09-28 2019-07-11 株式会社アネロファーマ・サイエンス ビフィドバクテリウム属細菌の遺伝子発現用プロモーター
JP7227918B2 (ja) 2017-03-28 2023-02-22 エンド ベンチャーズ リミテッド コラゲナーゼ産生の改良された方法
KR101915949B1 (ko) * 2018-01-09 2018-11-07 주식회사 쎌바이오텍 유전자 발현 카세트 및 그를 포함하는 발현벡터
CN116003538B (zh) * 2022-08-29 2026-03-20 广西壮族自治区兽医研究所 猪流行性腹泻病毒细菌样颗粒及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8503316A (nl) * 1985-11-29 1987-06-16 Stichting Nl I Zuivelonderzoek Werkwijze voor het bereiden van proteinen met behulp van gastheer-organismen, in het bijzonder melkzuurbacterien, welke recombinant dna-plasmiden met een hoge replicon-aktiviteit en een hoge promotor-aktiviteit voor het betreffende proteine-coderende gen bevatten, de van dergelijke recombinant dna-plasmiden voorziene gastheerorganismen, de recombinant dna-plasmiden zelve, de replicon-aktiviteit en promotor-aktiviteit coderende dna-fragmenten, alsmede de verkregen proteinen.
NL8701378A (nl) * 1987-06-12 1989-01-02 Nl Zuivelonderzoek Inst Dna-fragmenten, omvattende een melkzuurbacterie-specifiek regulatorgebied voor het tot expressie brengen van voor normaliter heterologe eiwitten coderende genen, op dergelijke dna-fragmenten gebaseerde recombinant-plasmiden, microorganismen, in het bijzonder melkzuurbacterien, welke deze recombinant-plasmiden, bevatten alsmede de met behulp van voorstaande microorganismen bereide heterologe eiwitten resp. produkten.
NL8803004A (nl) * 1988-12-07 1990-07-02 Bcz Friesland Bv Genetisch gemanipuleerde melkzuurbacterien en hun gebruik in de bereiding van kaas, alsmede recombinante plasmiden.
WO1992004451A1 (en) * 1990-08-30 1992-03-19 Genesit Oy Promoter probe vectors, able to replicate in e.coli, b.subtilis, lactococci and lactobacillus as well as uses thereof

Also Published As

Publication number Publication date
EP0677110B2 (de) 2010-01-27
AU675821B2 (en) 1997-02-20
DK0677110T4 (da) 2010-05-25
CA2152898A1 (en) 1994-07-21
DE69434196D1 (de) 2005-01-27
ES2235159T5 (es) 2010-05-11
PT677110E (pt) 2005-05-31
NZ286635A (en) 1997-06-24
EP0677110B1 (de) 2004-12-22
WO1994016086A1 (en) 1994-07-21
DK0677110T3 (da) 2005-01-24
DE69434196T3 (de) 2010-09-23
JPH08500739A (ja) 1996-01-30
JP3553065B2 (ja) 2004-08-11
AU5832594A (en) 1994-08-15
CA2152898C (en) 2003-04-29
DE69434196T2 (de) 2006-02-23
ES2235159T3 (es) 2005-07-01
EP0677110A1 (de) 1995-10-18
NZ259510A (en) 1997-06-24

Similar Documents

Publication Publication Date Title
ATE285476T1 (de) Eingefügter promoter enthaltendes rekombinantes milchsäure bakterium
KR830005355A (ko) 박테리아숙주내에서 각종 폴리펩타이드를 합성하는 방법 및 폴리펩타이드 dna
Scott et al. Electroporation-mediated transformation of lysostaphin-treated Clostridium perfringens
FI892065A0 (fi) Transformerade mjoelksyrebakterier.
Somkuti et al. Distribution and analysis of plasmids in Streptococcus thermophilus
GR3032790T3 (en) Materials and methods for hypersecretion of amino acids
HK87584A (en) Bacterial plasmid encoding human growth hormone
DE69124939D1 (de) Rekombinante DNS-Sequenzen kodierend für Enzyme frei von Feedback Inhibition, Plasmide diese Sequenzen enthaltend, transformierte Mikroorganismen nützlich für Produktion von aromatischen Aminosäuren, und deren Verfahren zur Herstellung durch Fermentation
Wood et al. Genetics of lactic acid bacteria
FI863891L (fi) Menetelmiä sekropiinin ja muiden heterologisten polypeptidien tuottamiseksi bakteeri-isännässä araB-promoottoria käyttäen sekä menetelmissä käyttökelpoisia replikoituvia ekspressiovälineitä, geneettisiä muodostelmia ja bakteereja
AU1509188A (en) Secretion of insulin-like growth factor-I in E. Coli
Obst et al. Two genes encoding the ß-galactosidase of Lactobacillus sake
CA2072007A1 (en) Cloning Vector for Use in Lactic Acid Bacteria and a Method for Constructing the Same
AU588793B2 (en) Method of expressing alpha-1-antitrypsin in bacteria
Kroyer et al. The promoter-proximal region of the Bacillus licheniformis penicillinase gene: Nucleotide sequence and predicted leader peptide sequence
JO1694B1 (en) New chemical products
EP0063494A3 (en) Method for producing protein from a microorganism, microorganisms for use in such method and creation thereof, vectors for use in said creation, and protein produced thereby, and transformant culture derived from said microorganisms
WO2001011060A3 (en) Method of isolating secretion signals in lactic acid bacteria and novel secretion signals isolated from lactococcus lactis
Gumbiner-Russo et al. The TGV transgenic vectors for single-copy gene expression from the Escherichia coli chromosome
IE59562B1 (en) Method for preparing proteins using transformed lactic acid bacteria
DE59109155D1 (de) Verfahren zur herstellung von vakzinen und ihre verwendung
FI911441A0 (fi) Menetelmä antibioottien tuottamiseksi, siinä käyttökelpoisia DNA-jaksoja, yhdistelmä-DNA-konstruktioita ja näitä sisältäviä mikrobikantoja
Molin et al. Biological Containment of bacteria and plasmids to be released in the environment
Chan Expression and purification of recombinant lysostaphin in Escherichia coli
US5021340A (en) Cloning vector, molecules of recombinant DNA, bacillus subtilis strains transformed with the said molecules and methods for the expression of heterologous genes and the production and secretion of proteins coded by the said genes

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0677110

Country of ref document: EP

UEP Publication of translation of european patent specification

Ref document number: 0677110

Country of ref document: EP