DE69433712D1 - Interkalatoren mit affinität für dna und ihre anwendung - Google Patents
Interkalatoren mit affinität für dna und ihre anwendungInfo
- Publication number
- DE69433712D1 DE69433712D1 DE69433712T DE69433712T DE69433712D1 DE 69433712 D1 DE69433712 D1 DE 69433712D1 DE 69433712 T DE69433712 T DE 69433712T DE 69433712 T DE69433712 T DE 69433712T DE 69433712 D1 DE69433712 D1 DE 69433712D1
- Authority
- DE
- Germany
- Prior art keywords
- intercalators
- affinity
- dna
- application
- hetero
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/14—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/10—Aza-phenanthrenes
- C07D221/12—Phenanthridines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8628593A | 1993-06-30 | 1993-06-30 | |
US86285 | 1993-06-30 | ||
PCT/US1994/007130 WO1995001341A1 (en) | 1993-06-30 | 1994-06-23 | Intercalators having affinity for dna and methods of use |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69433712D1 true DE69433712D1 (de) | 2004-05-19 |
DE69433712T2 DE69433712T2 (de) | 2005-04-14 |
Family
ID=22197554
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69433712T Expired - Lifetime DE69433712T2 (de) | 1993-06-30 | 1994-06-23 | Interkalatoren mit affinität für dna und ihre anwendung |
DE69435240T Expired - Lifetime DE69435240D1 (de) | 1993-06-30 | 1994-06-23 | Interkalatoren mit DNA-Affinität und Anwendungsverfahren |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69435240T Expired - Lifetime DE69435240D1 (de) | 1993-06-30 | 1994-06-23 | Interkalatoren mit DNA-Affinität und Anwendungsverfahren |
Country Status (8)
Country | Link |
---|---|
US (1) | US5582984A (de) |
EP (3) | EP1792897B1 (de) |
JP (1) | JP3856463B2 (de) |
AT (1) | ATE264307T1 (de) |
CA (1) | CA2162382C (de) |
DE (2) | DE69433712T2 (de) |
ES (2) | ES2218527T3 (de) |
WO (1) | WO1995001341A1 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5861247A (en) * | 1996-01-26 | 1999-01-19 | University Of Chicago | Rapid method to detect duplex formation in sequencing by hybridization methods |
SE506700C2 (sv) * | 1996-05-31 | 1998-02-02 | Mikael Kubista | Sond och förfaranden för analys av nukleinsyra |
US5730849A (en) * | 1996-09-30 | 1998-03-24 | Bio-Rad Laboratories, Inc. | High sensitivity dyes as stains for RNA bands in denaturing gels |
US6761816B1 (en) | 1998-06-23 | 2004-07-13 | Clinical Micro Systems, Inc. | Printed circuit boards with monolayers and capture ligands |
US7087148B1 (en) | 1998-06-23 | 2006-08-08 | Clinical Micro Sensors, Inc. | Binding acceleration techniques for the detection of analytes |
US6290839B1 (en) | 1998-06-23 | 2001-09-18 | Clinical Micro Sensors, Inc. | Systems for electrophoretic transport and detection of analytes |
US7312087B2 (en) * | 2000-01-11 | 2007-12-25 | Clinical Micro Sensors, Inc. | Devices and methods for biochip multiplexing |
US6787302B2 (en) * | 1999-10-25 | 2004-09-07 | Genprime, Inc. | Method and apparatus for prokaryotic and eukaryotic cell quantitation |
US6673568B1 (en) | 1999-10-25 | 2004-01-06 | Genprime, Inc. | Method and apparatus for prokaryotic and eukaryotic cell quantitation |
DE60042370D1 (de) | 1999-12-21 | 2009-07-23 | Ortho Clinical Diagnostics Inc | Detektion von nukleinsäuren |
US20020055134A1 (en) | 2000-07-24 | 2002-05-09 | Fleming James E. | Method and apparatus for viable and nonviable prokaryotic and eukaryotic cell quantitation |
AU2002245206A1 (en) | 2001-01-08 | 2002-07-30 | Tropix, Inc. | Dendritic chemiluminescent substrates |
JP4628594B2 (ja) * | 2001-06-25 | 2011-02-09 | 昭和電工株式会社 | 有機発光素子および発光材料 |
US9261460B2 (en) | 2002-03-12 | 2016-02-16 | Enzo Life Sciences, Inc. | Real-time nucleic acid detection processes and compositions |
US7166478B2 (en) * | 2002-03-12 | 2007-01-23 | Enzo Life Sciences, Inc., C/O Enzo Biochem, Inc. | Labeling reagents and labeled targets, target labeling processes and other processes for using same in nucleic acid determinations and analyses |
US9353405B2 (en) | 2002-03-12 | 2016-05-31 | Enzo Life Sciences, Inc. | Optimized real time nucleic acid detection processes |
GB0327524D0 (en) | 2003-11-26 | 2003-12-31 | Univ Glasgow | Heterocyclic aromatic compounds |
CN1918126B (zh) * | 2004-02-13 | 2010-07-21 | Dsmip资产公司 | 离子型uv-a防晒剂及含有该防晒剂的组合物 |
WO2007146811A2 (en) * | 2006-06-09 | 2007-12-21 | University Of Miami | Assessment of cellular composition and fractional viability and uses thereof |
US7943320B2 (en) * | 2008-12-30 | 2011-05-17 | Canon U.S. Life Sciences, Inc. | Unsymmetrical cyanine dyes for high resolution nucleic acid melting analysis |
WO2010110740A1 (en) * | 2009-03-25 | 2010-09-30 | Haiqing Gong | A fluidic apparatus and/or method for differentiating viable cells |
WO2013189043A1 (zh) * | 2012-06-20 | 2013-12-27 | 大连理工大学 | 一类绿光荧光菁染料、制备方法及其应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4665184A (en) * | 1983-10-12 | 1987-05-12 | California Institute Of Technology | Bifunctional molecules having a DNA intercalator or DNA groove binder linked to ethylene diamine tetraacetic acid |
US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4912208A (en) | 1987-06-29 | 1990-03-27 | Abbott Laboratories | Fluorophores for encapsulation into liposomes |
US4994385A (en) | 1987-10-30 | 1991-02-19 | Abbott Laboratories | Heterobifunctional coupling agents |
US5002883A (en) | 1987-10-30 | 1991-03-26 | Abbott Laboratories | Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents |
US5053520A (en) | 1988-09-22 | 1991-10-01 | Abbott Laboratories | Heterobifunctional maleimido containing coupling agents |
US5063109A (en) | 1988-10-11 | 1991-11-05 | Abbott Laboratories | Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents |
US5312921A (en) * | 1990-03-14 | 1994-05-17 | Regents Of The University Of California | Dyes designed for high sensitivity detection of double-stranded DNA |
GB9122525D0 (en) * | 1991-10-23 | 1991-12-04 | Isis Innovation | Dna bis-intercalators |
-
1994
- 1994-06-23 DE DE69433712T patent/DE69433712T2/de not_active Expired - Lifetime
- 1994-06-23 CA CA002162382A patent/CA2162382C/en not_active Expired - Fee Related
- 1994-06-23 ES ES94922010T patent/ES2218527T3/es not_active Expired - Lifetime
- 1994-06-23 ES ES07101154T patent/ES2331813T3/es not_active Expired - Lifetime
- 1994-06-23 EP EP07101154A patent/EP1792897B1/de not_active Expired - Lifetime
- 1994-06-23 EP EP20040001486 patent/EP1411047A1/de not_active Ceased
- 1994-06-23 AT AT94922010T patent/ATE264307T1/de not_active IP Right Cessation
- 1994-06-23 EP EP94922010A patent/EP0706515B1/de not_active Expired - Lifetime
- 1994-06-23 WO PCT/US1994/007130 patent/WO1995001341A1/en active IP Right Grant
- 1994-06-23 DE DE69435240T patent/DE69435240D1/de not_active Expired - Lifetime
- 1994-06-23 JP JP50356595A patent/JP3856463B2/ja not_active Expired - Fee Related
- 1994-06-29 US US08/268,043 patent/US5582984A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE264307T1 (de) | 2004-04-15 |
EP1792897A2 (de) | 2007-06-06 |
US5582984A (en) | 1996-12-10 |
EP0706515A1 (de) | 1996-04-17 |
WO1995001341A1 (en) | 1995-01-12 |
DE69435240D1 (de) | 2009-10-29 |
JPH09500871A (ja) | 1997-01-28 |
ES2331813T3 (es) | 2010-01-15 |
DE69433712T2 (de) | 2005-04-14 |
EP0706515B1 (de) | 2004-04-14 |
EP1792897B1 (de) | 2009-09-16 |
CA2162382A1 (en) | 1995-01-12 |
EP1792897A3 (de) | 2007-06-13 |
JP3856463B2 (ja) | 2006-12-13 |
EP1411047A1 (de) | 2004-04-21 |
CA2162382C (en) | 2006-04-11 |
ES2218527T3 (es) | 2004-11-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69433712D1 (de) | Interkalatoren mit affinität für dna und ihre anwendung | |
TR199700844T1 (xx) | Pirazolil-Benzoil T�revleri. | |
ES2065880T3 (es) | Proteina quimicamente modificada y obtencion de la misma. | |
ATE18902T1 (de) | Aminosaeurederivate und ihre therapeutischen verwendungen. | |
DE69716461D1 (de) | Antithrombotische organische nitrate | |
AR038429A2 (es) | Compuestos 15-alquil-16-hidroxilo de marcfortina | |
EA200000427A1 (ru) | Терапевтические применения хинолиновых производных | |
ATE196761T1 (de) | Inhibitoren retroviraler proteasen | |
YU123390A (sh) | Kondenzirane heterociklične spojine, njihova priprava in uporaba | |
NO933376L (no) | Morfinan-derivater og medisinsk anvendelse derav | |
KR830005201A (ko) | 2-r_3rn-3-r_1rn-5-py-6-q-피리딘 또는 그의 산부가염의 제조방법 | |
DE69410193D1 (de) | Neue verbindungen mit blutplättchenaggregationshemmender aktivität | |
PT74199B (de) | Neue trisubstituierte pyrimido<5,4-d>pyrimidine ihre herstel- lung und ihre verwendung als arzneimittel | |
ATE85978T1 (de) | 2-quaternaer-pyridinalkylthio- oder pyridinalkenylthiosubstituierte carbapeneme, diese enthaltende zusammensetzungen und ihre zusammenstellungen mit dhp-inhibitoren. | |
ATA152093A (de) | Neue guanidin- und amidinsalze von 7-amino-3-hydroxymethyl-3-cephem-4-carbonsäure | |
ATE232732T1 (de) | 2',5'-phosphorthioat/phosphodiester- oligoadenylate und ihre antiviralen verwendungen | |
DK7286D0 (da) | Octahydroindoliziner | |
ES2109244T3 (es) | Medicamentos que contienen compuestos de 3,7-diazabiciclo(3,3,1)nonano. | |
ES454501A1 (es) | Un procedimiento para la preparacion de acidos pirrolidon- carboxilicos sustituidos en n. | |
ATE80162T1 (de) | Antibiotisch wirkende isoxazolderivate, ihre herstellung und verwendung. | |
AR240943A2 (es) | Nuevo compuesto agroquimico denominado "sustancia n 51262" procedimiento para prepararlo y composicion que lo comprende" | |
ATE24487T1 (de) | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel. | |
ATE104986T1 (de) | Aminsalze von 1,4,2-oxazaphospholidin-2-alkoxy-2oxid-4-essigs|uren. | |
ATE65986T1 (de) | Propanolabkoemmlinge. | |
FI960588A0 (fi) | Mikrobisideina käytettäviä tiokarbamoyyliyhdisteitä |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |