DE69432370D1 - Proteinverkapselte, unlösliche, gasenthaltende Mikrokügelchen, deren Herstellung und Anwendung als bildgebende Mittel für Ultraschall - Google Patents

Proteinverkapselte, unlösliche, gasenthaltende Mikrokügelchen, deren Herstellung und Anwendung als bildgebende Mittel für Ultraschall

Info

Publication number
DE69432370D1
DE69432370D1 DE69432370T DE69432370T DE69432370D1 DE 69432370 D1 DE69432370 D1 DE 69432370D1 DE 69432370 T DE69432370 T DE 69432370T DE 69432370 T DE69432370 T DE 69432370T DE 69432370 D1 DE69432370 D1 DE 69432370D1
Authority
DE
Germany
Prior art keywords
gas
encapsulated
protein
ultrasound
insoluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69432370T
Other languages
English (en)
Other versions
DE69432370T2 (de
Inventor
Karel J Lambert
Sheila Benay Podell
Edward G Jablonski
Carl Hulle
Kenneth Hamilton
Rolf Lohrmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Molecular Biosystems Inc
Original Assignee
Molecular Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26775071&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69432370(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Molecular Biosystems Inc filed Critical Molecular Biosystems Inc
Publication of DE69432370D1 publication Critical patent/DE69432370D1/de
Application granted granted Critical
Publication of DE69432370T2 publication Critical patent/DE69432370T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
DE69432370T 1993-07-02 1994-07-04 Proteinverkapselte, unlösliche, gasenthaltende Mikrokügelchen, deren Herstellung und Anwendung als bildgebende Mittel für Ultraschall Expired - Lifetime DE69432370T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8671793A 1993-07-02 1993-07-02
US86717 1993-07-02
US18765694A 1994-01-26 1994-01-26
US187656 1994-01-26

Publications (2)

Publication Number Publication Date
DE69432370D1 true DE69432370D1 (de) 2003-04-30
DE69432370T2 DE69432370T2 (de) 2004-02-19

Family

ID=26775071

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69418101T Expired - Lifetime DE69418101T2 (de) 1993-07-02 1994-07-04 Die Herstellung von wasserunlöslichen Proteinverkapselten gasenthaltenden Mikrosphären,
DE69432370T Expired - Lifetime DE69432370T2 (de) 1993-07-02 1994-07-04 Proteinverkapselte, unlösliche, gasenthaltende Mikrokügelchen, deren Herstellung und Anwendung als bildgebende Mittel für Ultraschall

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69418101T Expired - Lifetime DE69418101T2 (de) 1993-07-02 1994-07-04 Die Herstellung von wasserunlöslichen Proteinverkapselten gasenthaltenden Mikrosphären,

Country Status (20)

Country Link
US (1) US5552133A (de)
EP (2) EP0633030B1 (de)
JP (3) JP2905598B2 (de)
KR (1) KR100218642B1 (de)
CN (1) CN1129910A (de)
AT (1) ATE179334T1 (de)
AU (1) AU683485B2 (de)
BR (1) BR9406993A (de)
CA (1) CA2166459C (de)
CZ (1) CZ350895A3 (de)
DE (2) DE69418101T2 (de)
ES (2) ES2134321T3 (de)
FI (1) FI956312A (de)
HU (1) HUT74827A (de)
IL (1) IL110185A (de)
NO (1) NO955351L (de)
NZ (1) NZ268826A (de)
PL (1) PL312387A1 (de)
TW (1) TW283646B (de)
WO (1) WO1995001187A1 (de)

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* Cited by examiner, † Cited by third party
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JP3809368B2 (ja) 2006-08-16
CA2166459A1 (en) 1995-01-12
DE69418101T2 (de) 1999-11-11
NO955351L (no) 1996-02-02
PL312387A1 (en) 1996-04-15
JP2905598B2 (ja) 1999-06-14
NO955351D0 (no) 1995-12-29
ES2134321T3 (es) 1999-10-01
FI956312A (fi) 1996-01-17
ES2195247T3 (es) 2003-12-01
JP3285544B2 (ja) 2002-05-27
NZ268826A (en) 1996-11-26
KR100218642B1 (ko) 1999-09-01
JPH11139995A (ja) 1999-05-25
EP0633030A1 (de) 1995-01-11
WO1995001187A1 (en) 1995-01-12
AU7218494A (en) 1995-01-24
IL110185A0 (en) 1994-10-21
CA2166459C (en) 2000-03-28
BR9406993A (pt) 1996-09-10
HU9503977D0 (en) 1996-03-28
AU683485B2 (en) 1997-11-13
DE69432370T2 (de) 2004-02-19
EP0885615B1 (de) 2003-03-26
US5552133A (en) 1996-09-03
CN1129910A (zh) 1996-08-28
TW283646B (de) 1996-08-21
FI956312A0 (fi) 1995-12-29
DE69418101D1 (de) 1999-06-02
EP0633030B1 (de) 1999-04-28
CZ350895A3 (en) 1996-10-16
JP2002167338A (ja) 2002-06-11
KR960703624A (ko) 1996-08-31
EP0885615A1 (de) 1998-12-23
IL110185A (en) 1999-05-09
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