DE69431498D1 - Loracarbef Hydrochlorid C1-C3 Alkohol-Solvate und deren Verwendungen - Google Patents
Loracarbef Hydrochlorid C1-C3 Alkohol-Solvate und deren VerwendungenInfo
- Publication number
- DE69431498D1 DE69431498D1 DE69431498T DE69431498T DE69431498D1 DE 69431498 D1 DE69431498 D1 DE 69431498D1 DE 69431498 T DE69431498 T DE 69431498T DE 69431498 T DE69431498 T DE 69431498T DE 69431498 D1 DE69431498 D1 DE 69431498D1
- Authority
- DE
- Germany
- Prior art keywords
- alcohol solvates
- hydrochloride
- loracarbef hydrochloride
- loracarbef
- disclosed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/077,305 US5550231A (en) | 1993-06-15 | 1993-06-15 | Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69431498D1 true DE69431498D1 (de) | 2002-11-14 |
DE69431498T2 DE69431498T2 (de) | 2003-06-26 |
Family
ID=22137301
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69431498T Expired - Fee Related DE69431498T2 (de) | 1993-06-15 | 1994-06-13 | Loracarbef Hydrochlorid C1-C3 Alkohol-Solvate und deren Verwendungen |
Country Status (13)
Country | Link |
---|---|
US (2) | US5550231A (de) |
EP (1) | EP0629625B1 (de) |
JP (1) | JP3474635B2 (de) |
KR (1) | KR100310947B1 (de) |
AT (1) | ATE225789T1 (de) |
BR (1) | BR9402406A (de) |
CA (1) | CA2125762A1 (de) |
DE (1) | DE69431498T2 (de) |
ES (1) | ES2184751T3 (de) |
FI (1) | FI108134B (de) |
HU (1) | HUT67489A (de) |
IL (1) | IL109989A (de) |
TW (1) | TW380139B (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA978515B (en) * | 1996-09-23 | 1999-03-23 | Lilly Co Eli | Intermediates and process for preparing olanzapine |
CA2506872A1 (en) * | 2002-11-21 | 2004-06-03 | Ranbaxy Laboratories Limited | Monohydrate solvates of loracarbef |
SI1603399T1 (sl) * | 2003-03-12 | 2010-04-30 | Lesaffre & Cie | Pekovski kvas, njegova uporaba in pekovski izdelki, ki jih lahko pridobimo iz njega |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4168376A (en) * | 1978-06-05 | 1979-09-18 | Eli Lilly And Company | Process for crystalline sodium cefamandole |
US4316958A (en) * | 1979-02-10 | 1982-02-23 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing optically active cephalosporin analogs |
JPS5672698A (en) * | 1979-11-14 | 1981-06-16 | Kyowa Hakko Kogyo Co Ltd | Preparation of optically active cephalosporin analogue |
US4332896A (en) * | 1979-04-14 | 1982-06-01 | Kyowa Hakko Kogyo Co., Ltd. | Process for producing cephalosporin analogs |
US4775751A (en) * | 1985-06-03 | 1988-10-04 | Eli Lilly & Company | Process for cephalexin hydrochloride alcoholates |
CA1334970C (en) * | 1987-10-06 | 1995-03-28 | Carol Elaine Pasini | Crystalline .beta.-lactam hydrate |
CA2002597C (en) * | 1988-11-14 | 1999-03-23 | Thomas M. Eckrich | Solvates of b-lactam antibiotic |
CA2002596A1 (en) * | 1988-11-14 | 1990-05-14 | Thomas M. Eckrich | Hydrates of b-lactam antibiotic |
US4977257A (en) * | 1988-11-14 | 1990-12-11 | Eli Lilly And Company | DMF solvates of a β-lactam antibiotic |
CA2034592C (en) * | 1990-01-26 | 2001-06-05 | Ralph R. Pfeiffer | Crystalline hydrochloride of new beta-lactam antibiotic and process therefor |
US5057607A (en) * | 1990-06-08 | 1991-10-15 | Eli Lilly And Company | Enantiomerically selective biocatalyzed acylation |
US5374719A (en) * | 1993-06-04 | 1994-12-20 | Eli Lilly And Company | Process for converting loracarbef dihydrate to loracarbef monohydrate |
US5399686A (en) * | 1993-06-04 | 1995-03-21 | Eli Lilly And Company | Loracarbef isopropanolate and a process for converting loracarbef isopropanolate to loracarbef monohydrate |
US5352782A (en) * | 1993-06-04 | 1994-10-04 | Eli Lilly And Company | Process for preparing crystalline β-lactam monohydrate |
US5412094A (en) * | 1993-06-28 | 1995-05-02 | Eli Lilly And Company | Bicyclic beta-lactam/paraben complexes |
-
1993
- 1993-06-15 US US08/077,305 patent/US5550231A/en not_active Expired - Lifetime
-
1994
- 1994-06-11 TW TW083105321A patent/TW380139B/zh not_active IP Right Cessation
- 1994-06-13 IL IL109989A patent/IL109989A/en not_active IP Right Cessation
- 1994-06-13 JP JP13023494A patent/JP3474635B2/ja not_active Expired - Fee Related
- 1994-06-13 AT AT94304230T patent/ATE225789T1/de not_active IP Right Cessation
- 1994-06-13 HU HU9401765A patent/HUT67489A/hu unknown
- 1994-06-13 ES ES94304230T patent/ES2184751T3/es not_active Expired - Lifetime
- 1994-06-13 FI FI942798A patent/FI108134B/fi not_active IP Right Cessation
- 1994-06-13 EP EP94304230A patent/EP0629625B1/de not_active Expired - Lifetime
- 1994-06-13 KR KR1019940013210A patent/KR100310947B1/ko not_active IP Right Cessation
- 1994-06-13 CA CA002125762A patent/CA2125762A1/en not_active Abandoned
- 1994-06-13 DE DE69431498T patent/DE69431498T2/de not_active Expired - Fee Related
- 1994-06-14 BR BR9402406A patent/BR9402406A/pt not_active Application Discontinuation
-
1995
- 1995-05-18 US US08/444,124 patent/US5578720A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
HU9401765D0 (en) | 1994-09-28 |
DE69431498T2 (de) | 2003-06-26 |
KR100310947B1 (ko) | 2001-12-28 |
US5550231A (en) | 1996-08-27 |
ATE225789T1 (de) | 2002-10-15 |
EP0629625B1 (de) | 2002-10-09 |
KR950000704A (ko) | 1995-01-03 |
JP3474635B2 (ja) | 2003-12-08 |
CA2125762A1 (en) | 1994-12-16 |
IL109989A0 (en) | 1994-10-07 |
TW380139B (en) | 2000-01-21 |
US5578720A (en) | 1996-11-26 |
FI108134B (fi) | 2001-11-30 |
BR9402406A (pt) | 1995-01-17 |
IL109989A (en) | 1998-06-15 |
EP0629625A1 (de) | 1994-12-21 |
FI942798A0 (fi) | 1994-06-13 |
JPH0770122A (ja) | 1995-03-14 |
FI942798A (fi) | 1994-12-16 |
ES2184751T3 (es) | 2003-04-16 |
HUT67489A (en) | 1995-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |