DE69431050D1 - PYRIDO[2,3-b](1,4)BENZODIAZEPINONE ALS M2-REZEPTORLIGAND ZUR BEHANDLUNG NEUROLOGISCHER STÖRUNGEN - Google Patents
PYRIDO[2,3-b](1,4)BENZODIAZEPINONE ALS M2-REZEPTORLIGAND ZUR BEHANDLUNG NEUROLOGISCHER STÖRUNGENInfo
- Publication number
- DE69431050D1 DE69431050D1 DE69431050T DE69431050T DE69431050D1 DE 69431050 D1 DE69431050 D1 DE 69431050D1 DE 69431050 T DE69431050 T DE 69431050T DE 69431050 T DE69431050 T DE 69431050T DE 69431050 D1 DE69431050 D1 DE 69431050D1
- Authority
- DE
- Germany
- Prior art keywords
- neurological disorders
- benzodiazepinone
- pyrido
- receptor ligand
- treating neurological
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4287293A | 1993-04-05 | 1993-04-05 | |
PCT/US1994/003720 WO1994022861A1 (en) | 1993-04-05 | 1994-04-05 | PYRIDO[2,3-b][1,4]BENZODIAZEPINONES AS M2 RECEPTOR LIGAND FOR THE TREATMENT OF NEUROLOGICAL DISORDERS |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69431050D1 true DE69431050D1 (de) | 2002-08-29 |
DE69431050T2 DE69431050T2 (de) | 2003-03-13 |
Family
ID=21924192
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69431050T Expired - Fee Related DE69431050T2 (de) | 1993-04-05 | 1994-04-05 | PYRIDO[2,3-b](1,4)BENZODIAZEPINONE ALS M2-REZEPTORLIGAND ZUR BEHANDLUNG NEUROLOGISCHER STÖRUNGEN |
Country Status (11)
Country | Link |
---|---|
US (1) | US5712269A (de) |
EP (2) | EP1120416A1 (de) |
JP (1) | JP3638950B2 (de) |
AT (1) | ATE221067T1 (de) |
AU (1) | AU688318B2 (de) |
CA (1) | CA2159815A1 (de) |
DE (1) | DE69431050T2 (de) |
DK (1) | DK0693070T3 (de) |
ES (1) | ES2180575T3 (de) |
PT (1) | PT693070E (de) |
WO (1) | WO1994022861A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6528529B1 (en) | 1998-03-31 | 2003-03-04 | Acadia Pharmaceuticals Inc. | Compounds with activity on muscarinic receptors |
ITMI991452A1 (it) * | 1999-07-01 | 2001-01-01 | Mediolanum Farmaceutici Srl | Antagonisti selettivi per i recettori m2 con struttura 5h-dibenzo b,fazepinica |
PE20010628A1 (es) * | 1999-10-01 | 2001-06-18 | Takeda Chemical Industries Ltd | Compuestos de amina ciclica, su produccion y su uso |
US20050154016A1 (en) * | 2002-04-19 | 2005-07-14 | Katsunori Takashima | Preventives for hiv infection |
CA2573674A1 (en) | 2004-07-16 | 2006-01-26 | Proteosys Ag | Muscarinic antagonists with parp and sir modulating activity as agents for inflammatory diseases |
JP2009506069A (ja) | 2005-08-26 | 2009-02-12 | ブレインセルス,インコーポレイティド | ムスカリン性受容体調節による神経発生 |
EP2258359A3 (de) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin |
MX362949B (es) * | 2008-12-04 | 2019-02-27 | Yu Chongxi | Composiciones de alta penetracion y sus aplicaciones. |
EP2379080A1 (de) | 2009-01-13 | 2011-10-26 | ProteoSys AG | Pirenzepin als otoprotektives mittel |
GB201510010D0 (en) | 2015-06-09 | 2015-07-22 | King S College London | PDD and BPD compounds |
GB201514928D0 (en) | 2015-08-21 | 2015-10-07 | King S College London | PDD compounds |
US20180339985A1 (en) | 2015-08-21 | 2018-11-29 | Femtogenix Limited | Pdd compounds |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH438343A (de) * | 1962-11-08 | 1967-06-30 | Thomae Gmbh Dr K | Verfahren zur Herstellung von 5,6-Dihydro-6-oxo-11H-pyrido (2,3-b) (1,4)-benzodiazepinen |
DE3735895A1 (de) * | 1987-10-23 | 1989-05-03 | Thomae Gmbh Dr K | Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE3818299A1 (de) * | 1988-05-30 | 1989-12-07 | Thomae Gmbh Dr K | Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
GB9000302D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Muscarinic receptor antagonists |
DE4112014A1 (de) * | 1991-04-12 | 1992-10-15 | Thomae Gmbh Dr K | Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung |
-
1994
- 1994-04-05 AT AT94914039T patent/ATE221067T1/de not_active IP Right Cessation
- 1994-04-05 ES ES94914039T patent/ES2180575T3/es not_active Expired - Lifetime
- 1994-04-05 AU AU66261/94A patent/AU688318B2/en not_active Ceased
- 1994-04-05 PT PT94914039T patent/PT693070E/pt unknown
- 1994-04-05 DE DE69431050T patent/DE69431050T2/de not_active Expired - Fee Related
- 1994-04-05 EP EP01200454A patent/EP1120416A1/de not_active Withdrawn
- 1994-04-05 WO PCT/US1994/003720 patent/WO1994022861A1/en active IP Right Grant
- 1994-04-05 JP JP52246994A patent/JP3638950B2/ja not_active Expired - Fee Related
- 1994-04-05 DK DK94914039T patent/DK0693070T3/da active
- 1994-04-05 CA CA002159815A patent/CA2159815A1/en not_active Abandoned
- 1994-04-05 EP EP94914039A patent/EP0693070B1/de not_active Expired - Lifetime
-
1995
- 1995-01-24 US US08/377,667 patent/US5712269A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES2180575T3 (es) | 2003-02-16 |
DE69431050T2 (de) | 2003-03-13 |
CA2159815A1 (en) | 1994-10-13 |
JP3638950B2 (ja) | 2005-04-13 |
ATE221067T1 (de) | 2002-08-15 |
AU6626194A (en) | 1994-10-24 |
JPH08510999A (ja) | 1996-11-19 |
US5712269A (en) | 1998-01-27 |
EP1120416A1 (de) | 2001-08-01 |
PT693070E (pt) | 2002-12-31 |
EP0693070B1 (de) | 2002-07-24 |
AU688318B2 (en) | 1998-03-12 |
EP0693070A1 (de) | 1996-01-24 |
DK0693070T3 (da) | 2002-11-11 |
WO1994022861A1 (en) | 1994-10-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: MANNKIND CORP. (N.D.GES.D. STAATES DELAWARE), DANB |
|
8339 | Ceased/non-payment of the annual fee |