DE69429770T2 - Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assays - Google Patents

Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assays

Info

Publication number
DE69429770T2
DE69429770T2 DE69429770T DE69429770T DE69429770T2 DE 69429770 T2 DE69429770 T2 DE 69429770T2 DE 69429770 T DE69429770 T DE 69429770T DE 69429770 T DE69429770 T DE 69429770T DE 69429770 T2 DE69429770 T2 DE 69429770T2
Authority
DE
Germany
Prior art keywords
analytical system
simple execution
accurate fast
fibrinogen
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69429770T
Other languages
English (en)
Other versions
DE69429770D1 (de
Inventor
J Oberhardt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiovascular Diagnostics Inc
Original Assignee
Cardiovascular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cardiovascular Diagnostics Inc filed Critical Cardiovascular Diagnostics Inc
Publication of DE69429770D1 publication Critical patent/DE69429770D1/de
Application granted granted Critical
Publication of DE69429770T2 publication Critical patent/DE69429770T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/4905Determining clotting time of blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Ecology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69429770T 1993-05-28 1994-05-27 Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assays Expired - Fee Related DE69429770T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/068,855 US5670329A (en) 1993-05-28 1993-05-28 Method and analytical system for performing fibrinogen assays accurately, rapidly and simply using a rotating magnetic field
PCT/US1994/005805 WO1994028168A1 (en) 1993-05-28 1994-05-27 Improved method and analytical system for performing fibrinogen assays accurately, rapidly and simply

Publications (2)

Publication Number Publication Date
DE69429770D1 DE69429770D1 (de) 2002-03-14
DE69429770T2 true DE69429770T2 (de) 2002-09-19

Family

ID=22085142

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69429770T Expired - Fee Related DE69429770T2 (de) 1993-05-28 1994-05-27 Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assays

Country Status (11)

Country Link
US (1) US5670329A (de)
EP (1) EP0700448B1 (de)
JP (1) JP3497862B2 (de)
KR (1) KR100351602B1 (de)
AT (1) ATE212674T1 (de)
CA (1) CA2163858C (de)
DE (1) DE69429770T2 (de)
ES (1) ES2170100T3 (de)
IL (1) IL109817A (de)
TW (1) TW326075B (de)
WO (1) WO1994028168A1 (de)

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US6321164B1 (en) * 1995-06-07 2001-11-20 Akzo Nobel N.V. Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade
US6429017B1 (en) 1999-02-04 2002-08-06 Biomerieux Method for predicting the presence of haemostatic dysfunction in a patient sample
EP0905520B1 (de) * 1997-09-29 2008-03-26 F. Hoffmann-La Roche Ag Gerät zur Abscheidung magnetischer Teilchen
DE69839294T2 (de) 1997-09-29 2009-04-09 F. Hoffmann-La Roche Ag Gerät zur Abscheidung magnetischer Teilchen
US6502040B2 (en) 1997-12-31 2002-12-31 Biomerieux, Inc. Method for presenting thrombosis and hemostasis assay data
US6893877B2 (en) 1998-01-12 2005-05-17 Massachusetts Institute Of Technology Methods for screening substances in a microwell array
SE9800590D0 (sv) 1998-02-26 1998-02-26 Global Hemostasis Inst Mgr Ab Determination of polymerization/coagulation in a fluid
US6165795A (en) * 1998-06-25 2000-12-26 Cardiovascular Diagnostics, Inc. Methods for performing fibrinogen assays using dry chemical reagents containing ecarin and magnetic particles
US20030059347A1 (en) 1998-09-18 2003-03-27 Roy A. Ostgaard Sample vial for use in preparing cytological specimen
US6562299B1 (en) * 1998-09-18 2003-05-13 Cytyc Corporation Method and apparatus for preparing cytological specimens
US6572824B1 (en) * 1998-09-18 2003-06-03 Cytyc Corporation Method and apparatus for preparing cytological specimens
ES2231167T3 (es) * 1999-02-04 2005-05-16 Biomerieux, Inc. Procedimiento y aparato para predecir la disfuncion hemostatica en una muestra de un paciente.
EP1165235B1 (de) 1999-03-19 2011-09-28 Life Technologies Corporation Methode zum sichten von mutierten zellen
US6417004B1 (en) * 1999-04-29 2002-07-09 Helena Laboratories Corporation Enhancing clot detection in activated clotting time and other fibrin endpoint based tests
US6586259B1 (en) * 1999-11-15 2003-07-01 Pharmanetics Incorporated Platelet/leukocyte interaction assay and reagent therefor
US20020151040A1 (en) 2000-02-18 2002-10-17 Matthew O' Keefe Apparatus and methods for parallel processing of microvolume liquid reactions
JP3581306B2 (ja) * 2000-03-31 2004-10-27 株式会社イソワ インキ粘度測定装置並びにインキ粘度調整方法及びその装置
US7179612B2 (en) 2000-06-09 2007-02-20 Biomerieux, Inc. Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality
US6581899B2 (en) * 2000-06-23 2003-06-24 Micronics, Inc. Valve for use in microfluidic structures
US6902904B2 (en) * 2001-08-27 2005-06-07 Pharmanetics Incorporated Coagulation assay reagents containing lanthanides
US6680177B2 (en) * 2001-12-07 2004-01-20 Cardiovascular Diagnostics, Inc. Low molecular weight heparin assay, system and reagent therefor
US8277753B2 (en) 2002-08-23 2012-10-02 Life Technologies Corporation Microfluidic transfer pin
EP1608952B1 (de) * 2002-12-20 2016-08-10 Life Technologies Corporation Assay vorrichtung und verfahren unter verwendung von mikrofluiden matrixstrukturen
US20060094108A1 (en) * 2002-12-20 2006-05-04 Karl Yoder Thermal cycler for microfluidic array assays
CA2559171A1 (en) 2004-03-12 2005-09-29 Biotrove, Inc. Nanoliter array loading
US9011329B2 (en) 2004-04-19 2015-04-21 Searete Llc Lumenally-active device
US8337482B2 (en) 2004-04-19 2012-12-25 The Invention Science Fund I, Llc System for perfusion management
US7850676B2 (en) 2004-04-19 2010-12-14 The Invention Science Fund I, Llc System with a reservoir for perfusion management
US8361013B2 (en) 2004-04-19 2013-01-29 The Invention Science Fund I, Llc Telescoping perfusion management system
US9801527B2 (en) 2004-04-19 2017-10-31 Gearbox, Llc Lumen-traveling biological interface device
US8092549B2 (en) 2004-09-24 2012-01-10 The Invention Science Fund I, Llc Ciliated stent-like-system
US8353896B2 (en) 2004-04-19 2013-01-15 The Invention Science Fund I, Llc Controllable release nasal system
DE102005028018A1 (de) * 2005-06-16 2006-12-21 Dade Behring Marburg Gmbh Verfahren zur Standardisierung von Gerinnungstesten
PT2047253E (pt) * 2006-07-17 2016-03-11 Universal Biosensors Pty Ltd Deteção eletroquímica da mobilidade das partículas magnéticas
EP2259069B1 (de) * 2008-03-31 2018-09-12 Sysmex Corporation Blutgerinnungsanalysegerät und blutgerinnungsanalyseverfahren
JP5312834B2 (ja) * 2008-03-31 2013-10-09 シスメックス株式会社 血液凝固分析装置、血液凝固分析方法、及び、コンピュータプログラム
JP5312835B2 (ja) * 2008-03-31 2013-10-09 シスメックス株式会社 血液凝固分析装置、血液凝固分析方法、及びコンピュータプログラム
JP2011069718A (ja) * 2009-09-25 2011-04-07 Sekisui Medical Co Ltd 血液凝固反応における血液凝固時間延長剤
CN107389932B (zh) * 2010-09-15 2019-11-22 德比奥法姆国际股份有限公司 用于从含纤维蛋白原的样品中分离目标分子或颗粒的方法
TWI499779B (zh) 2013-07-04 2015-09-11 Ind Tech Res Inst 檢測晶片及其使用方法
CN107003328A (zh) * 2014-12-18 2017-08-01 皇家飞利浦有限公司 用于确定生物样本中纤维蛋白原浓度的方法
KR102252259B1 (ko) * 2015-12-31 2021-05-14 주식회사 필로시스 혈액 응고 측정장치
JP6799245B2 (ja) * 2016-02-25 2020-12-16 国立研究開発法人産業技術総合研究所 血液のフィブリン量変化の計測方法
JP7191613B2 (ja) * 2018-09-26 2022-12-19 キヤノンメディカルシステムズ株式会社 血液凝固分析装置
US20220120768A1 (en) * 2018-12-07 2022-04-21 A&T Corporation Reagent for measuring fibrinogen
JP7359538B2 (ja) * 2018-12-07 2023-10-11 株式会社エイアンドティー フィブリノゲン測定試薬
JP7410652B2 (ja) * 2019-04-12 2024-01-10 株式会社エイアンドティー フィブリノゲンの定量方法
GB201911527D0 (en) * 2019-08-12 2019-09-25 Univ Dublin City Method for the determination of plasma fibrinogen concentration in whole blood samples
CN111307915B (zh) * 2020-02-24 2022-04-12 河南工业大学 一种检测血液中纤维蛋白原浓度的检测装置及检测方法
JP2021192009A (ja) * 2020-06-05 2021-12-16 株式会社エイアンドティー フィブリノゲン測定方法

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US5110727A (en) * 1987-04-03 1992-05-05 Cardiovascular Diagnostics, Inc. Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles
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US5120834A (en) * 1988-06-13 1992-06-09 American Biogenetic Sciences, Inc. Fibrin-specific monoclonal antibody
TW221493B (de) * 1990-07-10 1994-03-01 Cardiovascular Diagnostics Inc
DE69316293T2 (de) * 1992-09-09 1998-08-27 Tokuyama Corp Methode zur Bestimmung von Fibrinogen, trockenes Reagens hierfür und Verfahren zur Herstellung desselben

Also Published As

Publication number Publication date
EP0700448A1 (de) 1996-03-13
JP3497862B2 (ja) 2004-02-16
IL109817A (en) 1998-02-08
ATE212674T1 (de) 2002-02-15
KR960702528A (ko) 1996-04-27
JPH08510908A (ja) 1996-11-19
CA2163858C (en) 2004-07-13
ES2170100T3 (es) 2002-08-01
WO1994028168A1 (en) 1994-12-08
DE69429770D1 (de) 2002-03-14
IL109817A0 (en) 1994-08-26
CA2163858A1 (en) 1994-12-08
EP0700448A4 (de) 1998-10-07
TW326075B (en) 1998-02-01
EP0700448B1 (de) 2002-01-30
US5670329A (en) 1997-09-23
KR100351602B1 (ko) 2002-12-31

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee