DE69429770D1 - Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assays - Google Patents
Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assaysInfo
- Publication number
- DE69429770D1 DE69429770D1 DE69429770T DE69429770T DE69429770D1 DE 69429770 D1 DE69429770 D1 DE 69429770D1 DE 69429770 T DE69429770 T DE 69429770T DE 69429770 T DE69429770 T DE 69429770T DE 69429770 D1 DE69429770 D1 DE 69429770D1
- Authority
- DE
- Germany
- Prior art keywords
- analytical system
- simple execution
- accurate fast
- fibrinogen
- assay
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/4905—Determining clotting time of blood
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Ecology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/068,855 US5670329A (en) | 1993-05-28 | 1993-05-28 | Method and analytical system for performing fibrinogen assays accurately, rapidly and simply using a rotating magnetic field |
PCT/US1994/005805 WO1994028168A1 (en) | 1993-05-28 | 1994-05-27 | Improved method and analytical system for performing fibrinogen assays accurately, rapidly and simply |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69429770D1 true DE69429770D1 (de) | 2002-03-14 |
DE69429770T2 DE69429770T2 (de) | 2002-09-19 |
Family
ID=22085142
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69429770T Expired - Fee Related DE69429770T2 (de) | 1993-05-28 | 1994-05-27 | Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assays |
Country Status (11)
Country | Link |
---|---|
US (1) | US5670329A (de) |
EP (1) | EP0700448B1 (de) |
JP (1) | JP3497862B2 (de) |
KR (1) | KR100351602B1 (de) |
AT (1) | ATE212674T1 (de) |
CA (1) | CA2163858C (de) |
DE (1) | DE69429770T2 (de) |
ES (1) | ES2170100T3 (de) |
IL (1) | IL109817A (de) |
TW (1) | TW326075B (de) |
WO (1) | WO1994028168A1 (de) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6429017B1 (en) | 1999-02-04 | 2002-08-06 | Biomerieux | Method for predicting the presence of haemostatic dysfunction in a patient sample |
US6898532B1 (en) | 1995-06-07 | 2005-05-24 | Biomerieux, Inc. | Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample |
US6321164B1 (en) * | 1995-06-07 | 2001-11-20 | Akzo Nobel N.V. | Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade |
EP1712921A2 (de) * | 1997-09-29 | 2006-10-18 | F.Hoffmann-La Roche Ag | Vorrichtung zur Trennung von Magnetteilchen |
DE69839294T2 (de) | 1997-09-29 | 2009-04-09 | F. Hoffmann-La Roche Ag | Gerät zur Abscheidung magnetischer Teilchen |
US6502040B2 (en) | 1997-12-31 | 2002-12-31 | Biomerieux, Inc. | Method for presenting thrombosis and hemostasis assay data |
US6893877B2 (en) | 1998-01-12 | 2005-05-17 | Massachusetts Institute Of Technology | Methods for screening substances in a microwell array |
SE9800590D0 (sv) | 1998-02-26 | 1998-02-26 | Global Hemostasis Inst Mgr Ab | Determination of polymerization/coagulation in a fluid |
US6165795A (en) * | 1998-06-25 | 2000-12-26 | Cardiovascular Diagnostics, Inc. | Methods for performing fibrinogen assays using dry chemical reagents containing ecarin and magnetic particles |
US20030059347A1 (en) | 1998-09-18 | 2003-03-27 | Roy A. Ostgaard | Sample vial for use in preparing cytological specimen |
US6572824B1 (en) * | 1998-09-18 | 2003-06-03 | Cytyc Corporation | Method and apparatus for preparing cytological specimens |
US6562299B1 (en) * | 1998-09-18 | 2003-05-13 | Cytyc Corporation | Method and apparatus for preparing cytological specimens |
WO2000046603A1 (en) * | 1999-02-04 | 2000-08-10 | Akzo Nobel N.V. | A method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample |
CA2367912A1 (en) | 1999-03-19 | 2000-09-28 | Genencor International, Inc. | Multi-through hole testing plate for high throughput screening |
US6417004B1 (en) * | 1999-04-29 | 2002-07-09 | Helena Laboratories Corporation | Enhancing clot detection in activated clotting time and other fibrin endpoint based tests |
US6586259B1 (en) * | 1999-11-15 | 2003-07-01 | Pharmanetics Incorporated | Platelet/leukocyte interaction assay and reagent therefor |
US20020151040A1 (en) | 2000-02-18 | 2002-10-17 | Matthew O' Keefe | Apparatus and methods for parallel processing of microvolume liquid reactions |
JP3581306B2 (ja) * | 2000-03-31 | 2004-10-27 | 株式会社イソワ | インキ粘度測定装置並びにインキ粘度調整方法及びその装置 |
US7179612B2 (en) | 2000-06-09 | 2007-02-20 | Biomerieux, Inc. | Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality |
US20020015959A1 (en) * | 2000-06-23 | 2002-02-07 | Bardell Ronald L. | Fluid mixing in microfluidic structures |
US6902904B2 (en) * | 2001-08-27 | 2005-06-07 | Pharmanetics Incorporated | Coagulation assay reagents containing lanthanides |
US6680177B2 (en) | 2001-12-07 | 2004-01-20 | Cardiovascular Diagnostics, Inc. | Low molecular weight heparin assay, system and reagent therefor |
US8277753B2 (en) | 2002-08-23 | 2012-10-02 | Life Technologies Corporation | Microfluidic transfer pin |
AU2003302264A1 (en) | 2002-12-20 | 2004-09-09 | Biotrove, Inc. | Assay apparatus and method using microfluidic arrays |
US20060094108A1 (en) * | 2002-12-20 | 2006-05-04 | Karl Yoder | Thermal cycler for microfluidic array assays |
AU2005222618A1 (en) | 2004-03-12 | 2005-09-29 | Biotrove, Inc. | Nanoliter array loading |
US8092549B2 (en) | 2004-09-24 | 2012-01-10 | The Invention Science Fund I, Llc | Ciliated stent-like-system |
US8353896B2 (en) | 2004-04-19 | 2013-01-15 | The Invention Science Fund I, Llc | Controllable release nasal system |
US8361013B2 (en) | 2004-04-19 | 2013-01-29 | The Invention Science Fund I, Llc | Telescoping perfusion management system |
US9011329B2 (en) | 2004-04-19 | 2015-04-21 | Searete Llc | Lumenally-active device |
US7850676B2 (en) | 2004-04-19 | 2010-12-14 | The Invention Science Fund I, Llc | System with a reservoir for perfusion management |
US8337482B2 (en) | 2004-04-19 | 2012-12-25 | The Invention Science Fund I, Llc | System for perfusion management |
US9801527B2 (en) | 2004-04-19 | 2017-10-31 | Gearbox, Llc | Lumen-traveling biological interface device |
DE102005028018A1 (de) * | 2005-06-16 | 2006-12-21 | Dade Behring Marburg Gmbh | Verfahren zur Standardisierung von Gerinnungstesten |
US8974658B2 (en) * | 2006-07-17 | 2015-03-10 | Universal Biosensors Pty Ltd | Electrochemical detection of magnetic particle mobility |
EP3432002B1 (de) * | 2008-03-31 | 2023-11-08 | Sysmex Corporation | Blutgerinnungsanalysator und blutgerinnungsanalyseverfahren |
JP5312835B2 (ja) * | 2008-03-31 | 2013-10-09 | シスメックス株式会社 | 血液凝固分析装置、血液凝固分析方法、及びコンピュータプログラム |
JP5312834B2 (ja) * | 2008-03-31 | 2013-10-09 | シスメックス株式会社 | 血液凝固分析装置、血液凝固分析方法、及び、コンピュータプログラム |
JP2011069718A (ja) * | 2009-09-25 | 2011-04-07 | Sekisui Medical Co Ltd | 血液凝固反応における血液凝固時間延長剤 |
CN103108959B (zh) * | 2010-09-15 | 2017-06-09 | 德比奥法姆国际股份有限公司 | 用于从包括成分血的含纤维蛋白原的样品中分离目标分子或颗粒的方法 |
TWI499779B (zh) | 2013-07-04 | 2015-09-11 | Ind Tech Res Inst | 檢測晶片及其使用方法 |
CN113759134A (zh) | 2014-12-18 | 2021-12-07 | 皇家飞利浦有限公司 | 用于确定生物样本中纤维蛋白原浓度的方法 |
KR102252259B1 (ko) * | 2015-12-31 | 2021-05-14 | 주식회사 필로시스 | 혈액 응고 측정장치 |
JP6799245B2 (ja) * | 2016-02-25 | 2020-12-16 | 国立研究開発法人産業技術総合研究所 | 血液のフィブリン量変化の計測方法 |
JP7191613B2 (ja) * | 2018-09-26 | 2022-12-19 | キヤノンメディカルシステムズ株式会社 | 血液凝固分析装置 |
WO2020116556A1 (ja) * | 2018-12-07 | 2020-06-11 | 株式会社エイアンドティー | フィブリノゲン測定試薬 |
JP7410652B2 (ja) * | 2019-04-12 | 2024-01-10 | 株式会社エイアンドティー | フィブリノゲンの定量方法 |
JP7359538B2 (ja) * | 2018-12-07 | 2023-10-11 | 株式会社エイアンドティー | フィブリノゲン測定試薬 |
GB201911527D0 (en) * | 2019-08-12 | 2019-09-25 | Univ Dublin City | Method for the determination of plasma fibrinogen concentration in whole blood samples |
CN111307915B (zh) * | 2020-02-24 | 2022-04-12 | 河南工业大学 | 一种检测血液中纤维蛋白原浓度的检测装置及检测方法 |
JP7529446B2 (ja) * | 2020-06-05 | 2024-08-06 | 株式会社エイアンドティー | フィブリノゲン測定方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE792113A (fr) * | 1971-12-13 | 1973-05-30 | Technicon Instr | Melangeur de liquides contenant des particules magnetiques |
US3861197A (en) * | 1973-06-29 | 1975-01-21 | Technicon Instr | Method and apparatus for determining the viscosity of a liquid sample |
US4756884A (en) * | 1985-08-05 | 1988-07-12 | Biotrack, Inc. | Capillary flow device |
US5110727A (en) * | 1987-04-03 | 1992-05-05 | Cardiovascular Diagnostics, Inc. | Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles |
US4849340A (en) * | 1987-04-03 | 1989-07-18 | Cardiovascular Diagnostics, Inc. | Reaction system element and method for performing prothrombin time assay |
US5156974A (en) * | 1988-05-27 | 1992-10-20 | Biodata Corporation | Method for determining the fibrinogen level of a blood sample |
US5120834A (en) * | 1988-06-13 | 1992-06-09 | American Biogenetic Sciences, Inc. | Fibrin-specific monoclonal antibody |
TW221493B (de) * | 1990-07-10 | 1994-03-01 | Cardiovascular Diagnostics Inc | |
EP0587398B1 (de) * | 1992-09-09 | 1998-01-14 | Tokuyama Corporation | Methode zur Bestimmung von Fibrinogen, trockenes Reagens hierfür und Verfahren zur Herstellung desselben |
-
1993
- 1993-05-28 US US08/068,855 patent/US5670329A/en not_active Expired - Fee Related
-
1994
- 1994-05-27 KR KR1019950705305A patent/KR100351602B1/ko not_active IP Right Cessation
- 1994-05-27 WO PCT/US1994/005805 patent/WO1994028168A1/en active IP Right Grant
- 1994-05-27 EP EP94918100A patent/EP0700448B1/de not_active Expired - Lifetime
- 1994-05-27 JP JP50088495A patent/JP3497862B2/ja not_active Expired - Fee Related
- 1994-05-27 CA CA002163858A patent/CA2163858C/en not_active Expired - Fee Related
- 1994-05-27 DE DE69429770T patent/DE69429770T2/de not_active Expired - Fee Related
- 1994-05-27 AT AT94918100T patent/ATE212674T1/de not_active IP Right Cessation
- 1994-05-27 ES ES94918100T patent/ES2170100T3/es not_active Expired - Lifetime
- 1994-05-29 IL IL109817A patent/IL109817A/en not_active IP Right Cessation
- 1994-07-06 TW TW083106174A patent/TW326075B/zh active
Also Published As
Publication number | Publication date |
---|---|
US5670329A (en) | 1997-09-23 |
DE69429770T2 (de) | 2002-09-19 |
WO1994028168A1 (en) | 1994-12-08 |
KR100351602B1 (ko) | 2002-12-31 |
EP0700448A4 (de) | 1998-10-07 |
CA2163858A1 (en) | 1994-12-08 |
ES2170100T3 (es) | 2002-08-01 |
JP3497862B2 (ja) | 2004-02-16 |
CA2163858C (en) | 2004-07-13 |
IL109817A0 (en) | 1994-08-26 |
EP0700448B1 (de) | 2002-01-30 |
EP0700448A1 (de) | 1996-03-13 |
KR960702528A (ko) | 1996-04-27 |
ATE212674T1 (de) | 2002-02-15 |
JPH08510908A (ja) | 1996-11-19 |
IL109817A (en) | 1998-02-08 |
TW326075B (en) | 1998-02-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |